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Biomedical subjects

A F Romanchishen

Publications and source records attributed to A F Romanchishen.

At least 19 recordsLinked to original sources
PubMed2006

[A combination of diseases of the thyroid and asymptomatic adenoma of the parathyroid glands].

The authors have analyzed the cases of diagnosis of asymptomatic tumors of the parathyroid gland made during 8814 operations on the thyroid in the period from 1995 through 2004. The probability of detecting parathyroid incidentalomas in different forms of goiter was calculated which reaches 0.4%. A precision technique of operating allows the parathyroid tumors to be detected at the preclinical stage in all patients apart from a removal of the necessary volume of the thyroid tissue, guaranteed preservation of the laryngeal nerves and parathyroid glands.

Adenoma↗
PubMed2006

[Clinical symptoms of hyperparathyroidism and sizes of the parathyroid gland tumors].

Three groups of patients with different degrees of primary hyperparathyroidism were compared: 36 patients with asymptomatic tumors (incidentalomas) of the parathyroid glands, 20 patients with parathyreoadenomas of medium size and mild signs of hyperparathyroidism and 26 patients with large adenomas and severe manifestations of the disease. It was shown that asymptomatic tumors of the parathyroid glands (incidentalomas) might turn into clinically marked hyperparathyroidism as the size of the parathyroid tumors was growing.

Adolescent↗
PubMed2006

[Lymphadenectomy in patients with thyroid cancer: 30 years experience in dealing with the problem].

The article presents an analysis of results of surgical treatment of 2092 patients with cancer of the thyroid gland (CTG) using different kinds of lymphadenectomies. During 30 years 1076 different operations on the lymph nodes of the neck and mediastinum have been made by the same collective of surgeons. The improved strategy and technique of surgical treatment of patients with differentiated CTG, electrophysiological monitoring of the nerves resulted in less postoperative lethality (from 0.89% to 0%), less number of unilateral damages of the inferior laryngeal nerves (from 4.4% to 0.33%), bilateral pareses (from 2.1% to 0%), accessory nerves (from 2.7% to 0.1%). Surgical diagnostics of the regional metastases of cancer at the preclinical stage by means of intraoperative biopsy of not involved cervical lymph nodes of the 3-4 groups and the division of traumatic operations into 2 stages improved the immediate results and did not deteriorate the long-term results of treatment of CTG patients.

Humans↗
PubMed2006

[Decision on the strategy of treatment of patients with medullary cancer of the thyroid].

The work is based on an analysis of immediate and long-term results of treatment of 138 patients. It was shown that organ-sparing operations in combination with central lymphadenectomy were good for patients with intrathyroid carcinomas. Regional metastases observed by the moment of surgical treatment were a bad prognostic sign. The survival of patients without metastases was similar to that of patients with papillary and follicular cancer of the thyroid gland.

Adolescent↗
PubMed2005

[Special surgical treatment of patients with nodular tumors of the thyroid gland against the background of diffuse toxic goiter].

The authors have analyzed the results of treatment of 147 patients with diffuse toxic goiter (DTG) operated upon in the St. Petersburg Center of the surgery of the endocrine system organs. Questions of surgical strategy are considered when DTG is combined with nodular forms. The diagnostic potentialities of the methods used are assessed. The incidence of carcinomas in patients with nodular formations and DTG was determined. It was shown that the presence of nodules in the thyroid gland did not influence the nearest and distant results when using the corresponding surgical strategy.

Adenocarcinoma, Follicular↗
PubMed2005

[Surgical treatment of local-expanded forms of thyroid carcinoma].

An analysis of surgical treatment of 377 patients with advanced thyroid carcinoma is presented. The work included 82 combined, 90 expanded and 218 palliative operations (as well as 68 shave-resections). In 56 cases surgical interventions were two-or three-staged. This approach improved the immediate results and did not change the long-term results of treatment. It was shown that surgical treatment in advanced thyroid carcinoma gave good results in the majority of cases (recovery or long-term palliation). Combined and expanded operations were non effective in anaplastic thyroid carcinoma. In well-differentiated thyroid carcinoma the 10-year survival was noted in 70.2% of patients.

Adolescent↗
PubMed2005

[Postoperative recurrent goiter].

In the clinic of hospital surgery of the St. Petersburg state PMA operations on 19 000 patients with diseases of the thoracic gland were performed during 30 years. More than 1000 of these patients were operated on for recurrences. In most patients the recurrence repeated the primary disease of the thyroid gland. It is necessary to single out new diseases of the thyroid residue which make up 11% of the total number of observations. The causes of appearance of the postoperative recurrent goiter are different, the correct diagnosis can be made but after complex examination of the patients which allows to choose rational medical strategy.

Aged↗
PubMed2005

[Clinical peculiarities of diffuse toxic goiter in males].

A comparative analysis of thyrotoxicosis in 180 males and 121 females has shown that during the recent 15 years the number of males operated upon for diffuse toxic goiter (DTG) has become 2.6 times greater. Thyrotoxicosis in men is characterized by an aggressive course, is followed by cardiac complications, ophthalmopathy, impaired sexual function, appearance of foci of malignant growth, spread of diffuse hyperplasia of the thyroid gland behind the breast bone and trachea. Cessation of thyreostatic therapy resulted in quick recurrence of the disease. Repeated courses of treatment with thyreostatics increased the risk of irreversibility of changes in the heart muscle, impairment of regenerative abilities and massive lymphoid infiltration of the thyroid tissue followed by hypothyrosis. Early surgical treatment of men with DTG facilitated a rapid and reliable restoration of vitally important functions and recovery of most operated men and women.

Adolescent↗
PubMed2004

[Surgical strategies in the diagnosis and treatment of patients with differentiated thyroid cancer].

Results of examination of 215 patients with differentiated thyroid cancer (papillary, follicular, medullary) with various degrees of involvement of regional lymph nodes in the process are presented. The follow-up observation lasted from 2 till 10 years. It was established that metastases most frequently affect the jugular group of nodes so it was chosen for investigation in order to detect the micro-metastases at the subclinic stage. Division of the surgical treatment into two stages (biopsy of the regional lymph nodes and lymphodissection within 2-3 months in case of metastases) has allowed to improve early results and not worsen long-term results of treatment.

Adenocarcinoma, Follicular↗
PubMed2004

[Surgical treatment of sporadic and radiation-induced thyroid cancer in young patients].

An analysis of results of treatment of sporadic thyroid cancer in 68 children and juveniles and in 119 adult patients with radio-induced carcinomas irradiated in childhood after the Chernobyl APS accident in 1986 has revealed that the sporadic thyroid cancer in children and adults with radio-induced carcinomas are highly aggressive. For all this, radio-induced carcinomas are known to have aggressive local growth that in most cases required extended operations. The surgical treatment of carcinomas allows to get survival of the absolute majority of the patients.

Adolescent↗
PubMed2003

[Breast cancer in thyroid diseases].

The authors have analyzed 48 cases of breast cancer detected among more than 16,000 patients with thyroid pathology including thyroid carcinoma. It was established that breast cancer associated with thyroid pathology (thyroid cancer included) had specific features of the clinical course. Relative risk of breast carcinoma in thyroid cancer patients was not higher than the incidence in female population. Possible etiologic and pathogenic factors of the relationship between thyroid pathology and breast tumors are discussed. It is supposed that hypersecretion of prolactin and gonadotropins might play some role in such association. Radiotherapy and chemotherapy for breast carcinoma also can be predisposing factors to the development of subsequent thyroid pathology.

Adult↗