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Biomedical subjects

A F Tomilov

Publications and source records attributed to A F Tomilov.

At least 19 recordsLinked to original sources
PubMed2001

[Skin micro-hemangioma].

Microhemangiomas (MHA) observed on the skin are known under different terms: Tuzhilin's "red drops", senile hemangiomas, Campbell de Morgan spots, scrotal angiokeratomas Fordyce-Satton. Examination of 46 healthy subjects and 241 patients aged 15 to 76 years having different diseases has found that MHA occur both in healthy subjects and patients with different diseases. The number and size of MHA increase with age. The condition seems inheritable. Histologically, MHA are cavernous hemangiomas with thick connective tissue septa making impossible MHA dehematizing in diascopy. The conclusion is made on diagnostic insignificance of skin MHA.

Adolescent↗
PubMed1998

[The Chediak-Higashi syndrome].

The Chediak-Higashi syndrome is described. The morphology of the blood and bone marrow in a girl aged 4.5 months [correction of years] is described in detail. Hematological, immunological, and karyological characteristics of her parents are presented.

Biopsy, Needle↗
PubMed1991

[The erythrokaryocyte, the reticulocyte, the normocyte: their place in the scheme of erythropoiesis].

Estimation of reticulocyte and polychromatophil counts has shown that only 28.7-44.9 percent of blood reticulocytes and 61.7 percent of bone marrow reticulocytes are polychromatophilic. Polychromatophil count is approximately equal to the sum of classes I and II reticulocytes. Bone marrow smears staining to detect reticulocytes, followed by staining according to Romanovsky-Giemsa has shown that only solitary erythrokaryocytes did not contain granular or filament reticular substance. The authors analyze the following suppositions: eliminate reticulocytes from the erythropoiesis scheme, denote the former normoblasts erythrokaryocytes but not normocytes, demonstrate the possibility of mature red cell production from oxyphilic erythrokaryocytes and from polychromophilic erythrokaryocytes via polychromatophilic red cells in the scheme.

Bone Marrow Cells↗
PubMed1990

[Diagnosis of systemic mastocytosis using a semiquantitative method of assessing the mast cell population].

A study was made of bone marrow smears (17 puncture specimens) in 10 patients with systemic mastocytosis (SMC). The amount of mast cells (MC) in the myelograms widely ranged (from single cells to 39.6%) and in some cases, it was less than in healthy persons or in patients with other diseases. A semiquantitative method is suggested for estimating the population of MC which were distributed into four groups according to the degree of saturation with metachromatic granules. 1769 MC were estimated: from 61 to 200 in each specimen. In the control group (8 specimens from patients with leukemias and aplasias), 638 MC were estimated. The cytochemical coefficient (CCC) in SMC appeared to be equal to M +/- m = 1.34 +/- 0.11/M +/- 1.5 sigma = 0.6-2.1 l/, in the control group, it was 3.0 +/- 0.1/M +/- 1.5 sigma = 2.6-3.4/; p less than 0.001. The CCC less than or equal to 2.1 is considered to be one of the criteria for the diagnosis of SMC.

Aged↗
PubMed1985

[Various aspects of the classification, clinical course and diagnosis of monocytoid and histiocytoid hemoblastoses].

Analysis of the reported data and authors' observations (41 patients with monocytoid leukemias and 21 patients with histiocytoses) made it possible to conclude that in most cases, histiocytoses are multifocal tumors with diverse morphological manifestations. A classification of histiocytoid tumors is offered with regard to the process extent, the nature of bone marrow damage, morphological features, the degree of final differentiation of tumor cells, and the clinical and laboratory signs of neoplastic activity.

Adolescent↗
PubMed1982

[Clinical application of the international histological and cytological classification of hematologic and lymphatic neoplasms].

The first part of the International classification of neoplastic diseases of haemopoietic and lymphatic tissues by Mathé et al is discussed. The classification is exhaustive but the Table does not include all varieties of hemoblastoses mentioned in the explanatory text and shown in illustrations. Some of the terms seem disputable or inaccurate. The structure of leukemias (623 cases) based on the data of the Sverdlovsk regional haematological centre for 1975-1979 is presented, as reconsidered according to the above classification. The role of trepanobiopsies in diagnosis of leukemias is emphasized.

Bone Marrow↗