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Biomedical subjects

A Faúndes

Publications and source records attributed to A Faúndes.

86 records · Page 5Linked to original sources
PubMed1981

Sperm migration at different stages of the menstrual cycle.

Sperm migration to the upper genital tract was studied in 15 volunteers who were to be surgically sterilized to see if sperm migration to the upper genital tract is consistent during different stages of the menstrual cycle. Five subjects underwent surgery during the midproliferative phase, five during the periovulatory period and five during the secretory phase. The stage of the cycle was determined by endometrial and ovarian biopsy at the time of surgery. Volunteers had a single coitus 5-12 h before surgery, confirmed by Sims-Huhner test. Sperm were found in the uterus and at least one oviduct in all five subjects studied during the periovulatory phase, and only in two of the five cases undergoing surgery during either of the other phases. A good correlation was also observed between presence and number of sperm in the upper genital tract and quality of Sims-Huhner test. However, neither the cycle stage nor the postcoital test had an absolute prognostic value over sperm migration.

Adult↗
PubMed1981

Sperm suppression with monthly injections of medroxyprogesterone acetate combined with testosterone enanthate at a high dose (500 mg).

The combination of an initial injection of 1000 mg of depot medroxyprogesterone acetate and 500 mg of testosterone enanthate, followed by monthly administration of 150 mg and 500 mg of the same drugs, was tested in 10 healthy males aged 28 through 39, with pre-treatment sperm counts of 50 x 10(6)/ml or more. Eight of the subjects achieved azoospermia, and the sperm counts of the other two declined 0.09 ad 5 million/ml. This last subject was highly refractory to treatment as his sperm density recovered to 27 million sperm/ml at the 6th month of continuous therapy. FSH was severely depressed during the entire treatment period. LH fell to 30--40% of normal values in the first two months and then showed a slow recovery during maintenance treatment. Testosterone measured one month after each injection was between 10 and 30% of pre-treatment values. Three of the subjects had increased libido and potency, none had decreased sexual drive or potency. All subjects gained weight with the average gain being 6 kg. The increase in the dose of testosterone enanthate to 500 mg/ng did not improve the results as compared to previous trials using lower doses of TE.

Adult↗
PubMedDate not supplied

[Impact of contraceptive methods on women's lives: the case of tubal ligation].

This study focused on the long-term consequences of tubal ligation on women's lives. Women 30 to 49 years old living in Campinas, State of São Paulo (Brazil), were interviewed: 236 sterilized at least five years prior to the interview and 236 non-sterilized women. Their experiences with the currently used contraceptive methods were compared with regard to satisfaction, benefits, and damage attributed to the method, feelings of regret, and perception of effects on their health, body, menstruation, sex, affective and family life, job, studies, economic status, and self-esteem. Scores were created to compare the groups in relation to self-esteem, well-being/quality of life, relationship with partner, and gender issues. Satisfaction with the currently used contraceptive method was significantly higher among sterilized women, although they more frequently reported having regretted being sterilized at some moment in time. Relatively more sterilized women felt that the contraceptive method had improved their sex lives and economic status, while producing a negative effect on their menstruation. No significant difference was observed between the groups with regard to the scores studied.

Adult↗
PubMedDate not supplied

[Mortality in childbearing-age women in Campinas, São Paulo (1985-1994)].

To provide a profile of the main health problems in childbearing-age women, we studied all 3,086 death certificates from the SEADE Foundation for women from 10 to 49 years of age and residing in the municipality of Campinas, from January 1, 1985, to December 31, 1994. The primary cause of death was identified and classified according to the 10th review of the ICD. Population data were obtained from the Laboratory for Epidemiological Analyses and Research, UNICAMP. One-fourth of the deaths were cardiovascular in origin, one-fifth were from external causes, and almost 20% were due to neoplasms. Maternal mortality was the ninth cause of death. External causes predominated in the 10-to-34-year age group, as compared to cardiovascular diseases and neoplasms in the 35-to-49-year group. Most alarming were the predominance of traffic accidents among causes of death in women up to age 34 (greater than AIDS during the study period) and the high mortality rate from homicides.

Adolescent↗
PubMedDate not supplied

Prevalence of HIV and Treponema pallidum infections in pregnant women in Campinas and their association with socio-demographic factors.

The anonymous seroprevalence of HIV and syphilis was studied by collecting umbilical cord blood samples from 5,815 women who gave birth in Campinas' hospitals throughout a six-month period. ELISA and Western blot were used for HIV, and VDRL and TPHA for Treponema pallidum screening. While maintaining the anonymity of the women, information was recorded on the hospital of origin, divided into university (public) and private hospitals, as well as on the form of payment (social security, private insurance or direct payment), age, marital status, education, employment and place of residence. Seroprevalence was 0.42 percent for HIV and 1.16 percent for syphilis. There was a significant correlation between a positive reaction to the two infections (p = 0.02). After univariate and logistic regression analysis, only university hospitals were shown to be associated with seropositivity for HIV, whereas the same variable and an older age were associated with syphilis. All positive reactions were found either in public hospitals or among social security patients treated at private institutions. The conclusion was that HIV infection is becoming almost as prevalent as syphilis among this population, and affects primarily the lower socio-economic strata. This suggests that routine, voluntary HIV serology should be considered and discussed with patients during prenatal or delivery care whenever a population shows a seroprevalence close to or greater than 1 percent.

Blotting, Western↗
PubMedDate not supplied

[Recent advances in contraception and family planning].

This paper describes the most recent advances in the field of contraception and family planning. The author discusses the evolution of hormonal contraception--reduction in dosage, new routes of administration, new progestogens, counseling and patient selection, improved hormonal contraceptives--intrauterine contraception--IUDS design adapted to the uterine cavity, intrauterine release of contraceptive substances, importance of insertion techniques, improved IUDS--and family planning as an instrument of public health.

Abortion, Induced↗
PubMedDate not supplied

[Interventions to reduce maternal mortality].

The authors comment a proposal to adopt measures to reduce maternal death and suggest four levels of action: 1) actions aimed at improving the knowledge about the number and factors associated to high risk maternal mortality during pregnancy, delivery and puerperium; they comment on the undernumeration of maternal death cases and propose an improvement in vital statistics, epidemiologic investigation and the creation of maternal mortality committees; 2) action to assist pregnancy, delivery and puerperium, to increase both the coverage and the quality of medical care, prenatal care, institutional care to delivery, and post-partum care; 3) action to prevent pregnancy in women with high risk of maternal mortality, improving diagnosis and treatment of diseases that increase maternal risk, and promoting contraception for these cases; 4) other actions aimed at reducing the risk of death brought about by induced abortion.

Abortion, Spontaneous↗
PubMedDate not supplied

[The experience of the Resting Home at the Center for Integral Women's Health Care of the State University of Campinas, Brazil].

The CAISM--Center for Integral Women's Health Care, of the Unicamp--State University of Campinas created a low complexity unit called a "Resting Home" according to the model adopted by other tertiary care centers in Brazil and in other countries. With 35 beds, the Resting Home staff includes two registered nurses, one social worker, and one occupational therapist. The institution admits women who have a high risk of acute complications of pregnancy or who require frequent check-up, mothers of premature babies under care in neonatal units who require their mother's breast feeding, and gynecological cancer patients who are in the process of staging and final diagnosis, or who are under frequent sessions of radiotherapy or chemotherapy. The common characteristic is that all of them need to go frequently to the outpatient services of the hospital, they live far away from the hospital, and they cannot afford rapid and easy transportation from their homes. The Resting Home offers them lodging and food, and a minimum of comfort (occupational therapy, TV, reading) at a cost that is only a small fraction of the cost of an inpatient. The authors present the statistics for the first 31 months of operation.

Brazil↗
PubMedDate not supplied

The effectiveness of intravaginal misoprostol (Cytotec) in inducing abortion after eleven weeks of pregnancy.

At Maputo Central Hospital in Mozambique, intravaginal misoprostol, a PGE2 methyl-analogue, was used by 169 women whose request for interruption of pregnancy had been approved. The drug was used by women who had completed between 12 and 23 weeks of gestation. The initial dose was 800 micrograms, repeated 24 hours later if abortion had not occurred or was not in progress. The treatment was considered a failure when abortion was not advanced by 48 hours after the initial dose, and curettage was performed in all but one of such cases. During the course of the study, the dosage was successively reduced to 600, 400, and 200 micrograms. Abortion was successfully induced in 154 women (91.1 percent); there were 10 failures (5.9 percent), and five women (3.0 percent) dropped out of the study. The mean time from initial dose to abortion was 14.3 hours. No significant association of success rate and time from dosage to expulsion was found with age, parity, previous abortion, or gestational age. Preventive vacuum aspiration of the uterine cavity was carried out on all subjects.

Abortion, Induced↗