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Biomedical subjects

A Farah

Publications and source records attributed to A Farah.

At least 19 recordsLinked to original sources
PubMed1995

ECT administration to a hyperthyroid patient.

There are few reported convincing cases of hyperthyroid depressed patients receiving electroconvulsive therapy (ECT). We describe a depressed 66-year-old woman with catatonic depression diagnosed with new-onset hyperthyroidism due to Grave's disease. After commencing propylthiouracil, her Grave's disease was partially treated, but her depression was no better. She subsequently received a course of seven ECT with resolution of her depression and no adverse sequelae.

Aged↗
PubMed1995

[Hydatid cyst of the psoas].

Recurrent hydatic cyst of the psoas is an exceptional disease in France but should not be missed in patients coming from endemic areas. A case report and a review of the literature on the aetiopathology, diagnosis and therapy are presented. Abdominal pelvic CT scan should give the diagnosis. Surgical treatment is indicated, with complete exeresis to avoid early relapse.

Adult↗
PubMed1994

Effects of caffeine pretreatment on measures of seizure impact.

Caffeine lengthens electroconvulsive therapy (ECT) seizures but has not been demonstrated to lower seizure threshold, nor to directly improve treatment outcome. We examined the effects of caffeine upon three recently proposed physiologic measures of seizure quality or impact: electroencephalography voltage suppression ratios, seizure regularity, and heart rate. None of these measures differed significantly in depressed inpatients randomly pretreated with either i.v. caffeine or saline on successive treatments during a course of right unilateral ECT. Newly defined measures of seizure impact may help identify ECT seizures of differing clinical efficacy, but these measures did not discriminate our caffeine and placebo conditions.

Aged↗
PubMed1992

[Respiratory pathology of sleep and the upper airways].

Respiratory disorders in the upper respiratory tract during sleep are most often part of a continuous pathological process of long standing. Schematically, three clinical syndromes with increasing severity are described: breathing with the mouth open, snoring and the sleep apnea syndrome. These conditions always include a functional maxillofacial perturbation, which may be associated to a constitutional or acquired morphological disorder. Besides the medical approach itself, the treatment sometimes is surgical, always orthopedic. The earlier it is initiated, the more effective, simple and unconstraining it is.

Adult↗
PubMed1989

[Extracorporeal lithotripsy in the treatment of biliary calculi].

The authors present their experience from February 1988 with biliary lithotripsy in 125 patients. They review the protocol inclusion criteria and the various forms of complementary medical treatment. From this group, 30% of the patients underwent cholecystectomy, 45% received medical treatment and only 25% did not eventually require complementary medical therapy.

Cholelithiasis↗
PubMed1989

[Obstructive left colonic cancer. Retrospective analysis of the therapeutic attitude in a series of 40 recent cases].

In a series of 40 cancers involving the descending and sigmoid colon and producing true acute obstruction, the following were performed: 16 colostomies of first intention (including 11 palliative); 14 resections with colostomy (Hartmann type); 9 resection-anastomoses (including 3 protected); 1 attempt at laser treatment for non consent to surgery. Only 22 patients were theoretically suitable for anastomosis (18 contraindications due to invasive cancer or peritonitis); this was in fact carried out in 9 cases. Thus, if single stage surgery represents the ideal, it cannot be systematically applied; on the other hand, tumor resection can often be performed. It would seem that the use of per-operative colonic lavage can increase the percentage of single stage surgery, though there will always be a place for Hartmann or Bouilly-Volkmann type procedures, future reestablishment of continuity being facilitated by the use of surgical staples (EEA type).

Acute Disease↗
PubMed1989

[Intubation of proximal biliary stenoses using a new surgical endoprosthesis].

Thirty patients with high biliary tract strictures were treated by a new surgical endoprosthesis, the tolerance of which has been tested experimentally. It is flexible, radiopaque and incompressible with spurs which prevent migration. Following choledochotomy, the endoprosthesis is positioned surgically above the sphincter of Oddi, thereby avoiding ascending cholangitis. Twenty-nine cases presented with neoplastic compression by an inoperable cancer and one case had an early postoperative stricture with loss of substance after right hepatectomy for hepatic metastases. The 29 cancers included 13 gallbladder cancers, 11 cholangiocarcinomas, 10 of which were hilar, and 5 metastatic compressions due to gastrointestinal adenocarcinomas. In three cases, there was loss of substance of biliary tract after intubation. The operative mortality was 3.3% (one pulmonary complication). Resolution of jaundice was obtained in all but 2 cases and pruritus always resolved. The mean survival of the patients with cholangiocarcinoma was 12.2 months while that of patients with gallbladder cancer was 6.33 months with indices of satisfaction, calculated by Bismuth's method, varying between 71% (gallbladder cancer) and 93.5% (hilar cholangiocarcinoma). The patient operated for benign stricture secondary to a hepatectomy scar for metastases died from lung metastases without jaundice after 48 months. The only late complications were 2 cases of cholangitis treated medically, one of which was due to obstruction of the endoprosthesis at the 13th month. The authors conclude that this new type of surgical endoprosthesis constitutes an alternative in the palliative treatment of neoplastic hilar compressions.

Cholestasis↗
PubMed1986

The effects of milrinone (Win 47203) on the coronary blood flow and oxygen consumption of the dog heart-lung preparation.

Milrinone is a new bipyridine-positive inotropic agent that is closely related to amrinone. In the nonfailing heart, coronary blood flow was increased and coronary bed resistance was decreased by milrinone, most probably by a direct action of milrinone on the coronary vasculature. Oxygen consumption was increased at the lower workloads. In the failing heart milrinone (0.1 to 0.5 mg/L of blood) increased cardiac output and coronary blood flow and reduced coronary vascular resistance. With the 0.1 mg dose oxygen consumption was reduced, especially at the high workloads, and was not significantly changed at the low work levels. With higher doses of milrinone oxygen consumption of the heart was not changed significantly while external work was increased. These data show that milrinone can increase the work of the heart with a decrease or no significant change in oxygen consumption of the isolated failing heart. The use of this drug in heart failure accompanied by restricted blood flow may thus be indicated.

Animals↗
PubMed1983

The search for a digitalis substitute II milrinone (Win 47203). Its action on the heart-lung preparation of the dog.

Milrinone (Win 47203) is a dipyridine related to amrinone, which is about 20-50 times as effective as amrinone when assayed on cardiac contractility. In dog heart-lung preparations, milrinone in a concentration of 0.25-0.5 microM produced a near maximal positive inotropic effect on a variety of acute heart failures. This dosage produced a minimal increase in heart rate and reduced the PR interval. Large doses of milrinone did not produce cardiac irregularities and in Nifedipine heart failure with ventricular irregularities, it eliminated these irregularities. Papaverine-induced heart failure was resistant to ouabain, epinephrine and milrinone therapy. In the presence of positive inotropic amounts of papaverine or theophylline, a pentobarbital heart failure was superimposed. This heart failure responded poorly to milrinone, although it responded to both the addition of epinephrine and ouabain. It is thus possible that milrinone, papaverine and theophylline have closely related sites of action.

Animals↗