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Biomedical subjects

A Feingold

Publications and source records attributed to A Feingold.

At least 37 records · Page 2Linked to original sources

Gender differences in mate selection preferences: a test of the parental investment model.

Evolutionary-related hypotheses about gender differences in mate selection preferences were derived from Triver's parental investment model, which contends that women are more likely than men to seek a mate who possesses nonphysical characteristics that maximize the survival or reproductive prospects of their offspring, and were examined in a meta-analysis of mate selection research (questionnaire studies, analyses of personal advertisements). As predicted, women accorded more weight than men to socioeconomic status, ambitiousness, character, and intelligence, and the largest gender differences were observed for cues to resource acquisition (status, ambitiousness). Also as predicted, gender differences were not found in preferences for characteristics unrelated to progeny survival (sense of humor, "personality"). Where valid comparisons could be made, the findings were generally invariant across generations, cultures, and research paradigms.

Female↗

Extracting maximum validity from the WAIS.

Recent research (Feingold, 1982) on the incremental validity of the WAIS has found that the Vocabulary and Information subtests are each as valid as the Full Scale IQ. The present WAIS review demonstrated that weighting subtests that differ in validity equally in the computation of the IQ is responsible for reducing potential validity. Two main conclusions emerged from these data. One, Vocabulary and Information in concert yield a measure that has greater validity than either subtest by itself. Two, the addition of a third test in a stepwise multiple regression in which Vocabulary and Information already have been added will not result in a consistent increase in validity. These findings must be considered tentative, but can serve as a guide for devising research designs to validate the recent revision of the WAIS (WAIS-R).

Achievement↗

Differences between employed and unemployed alcoholic inpatients in trouble for drinking and denial.

The Trouble-Due-to-Drinking scale and the Denial scale of the MMPI were administered to two groups of inpatients of low socioeconomic status, an employed group (27 men, 3 women) and an unemployed one (44 men, 12 women), at a state alcoholism facility in an inner city catchment area. The former were significantly older than the latter; Ms = 40.4 and 35.5 yr., respectively. The Trouble scale correctly identified 98% of the unemployed group but only 83% of the employed group. The unemployed scored significantly higher on MMPI Denial and significantly lower on the Trouble scale than the unemployed. The Pearson r between scores on the two measures was negative and significant for the combined sample and for the unemployed as well, whereas r for the unemployed was negative but nonsignificant. It was concluded that the unemployed group was less given to the use of denial and had encountered more alcohol-related problems than the employed group.

Alcoholism↗

Suxamethonium infusion rate and observed fasciculations. A dose-response study.

Suxamethonium chloride (Sch) was administered i.v. to 36 adult males at six rates: 0.25 mg s-1 to 20 mg s-1. The infusion was discontinued either when there was no muscular response to tetanic stimulation of the ulnar nerve or when Sch 120 mg was exceeded. Six additional patients received a 30-mg i.v. bolus dose. Fasciculations in six areas of the body were scored from 0 to 3 and summated as a total fasciculation score. The times to first fasciculation, twitch suppression and tetanus suppression were inversely related to the infusion rates. Fasciculations in the six areas and the total fasciculation score were related directly to the rate of infusion. Total fasciculation scores in the 30-mg bolus group and the 5-mg s-1 and 20-mg s-1 infusion groups were not significantly different.

Dose-Response Relationship, Drug↗

The pharmacokinetics of metabolism of inhalation anaesthetics. A simulation study.

The non-steady state metabolism of inhalation anaesthetics during anaesthesia and recovery was simulated with a linear and non-linear whole body compartmental model. These two models were studied for nine anaesthetics during 1-MAC anaesthesias lasting 1, 4 and 8 h and recovery from 5 to 10 days. Both models demonstrated significant metabolism for several days following anaesthesia. For the linear model, both the percentage and the molar quantity of anaesthetic metabolized increased with increased duration of anaesthesia, increased anaesthetic fat solubility and increased assumed rate of hepatic metabolism. For the non-linear model, the duration of anaesthesia had little effect on the percentage metabolized but demonstrated increased molar quantities of anaesthetic metabolized with increased duration of anaesthesia and increased fat solubility. The agreement between the results obtained from the non-linear model and experimental data in the literature suggests that many inhalation anaesthetics belong to a class of xenobiotics whose biotransformation is limited by the same or similar non-linear rate-limiting step(s). A difference in the quantities of anaesthetic metabolized would be a direct consequence of the tissue solubilities of the anaesthetic.

Anesthesia, Inhalation↗

A latex bag tonometer for determining the anaesthetic blood/gas partition coefficient.

Many techniques for measurement of the tissue/gas partition coefficient are valid. Each has specific advantages and shortcomings. All the methods require suitable analytic equipment and means for controlling temperature. The disadvantages of a particular technique, the ability to cope with them and the availability of the necessary apparatus are the determining factors in choosing the best method. The latex bag tonometer has a precision and ease which compares favourably with previously described techniques for measuring anaesthetic blood/gas partition coefficients. The technique was successfully used to show the effect of in vivo haemodilution on the halothane blood/gas partition coefficient.

Anesthesiology↗