Complete heart block complicating retrograde left heart catheterization.
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Biomedical subjects
Publications and source records attributed to A Feit.
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Serial coronary angiography done in a patient with left ventricular mural thrombus demonstrated abnormal neovascularity from the coronary artery to the left ventricle occurring eight to eighteen months after thrombus formation. This is the first case report describing such late neovascularization of left ventricular mural thrombus. The formation of coronary neovascularity to left ventricular mural thrombus need not occur in the early stage of the thrombus.
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Left internal mammary artery (LIMA) angiography was performed with diagnostic coronary angiography in 130 cases for which the coronary findings made use of the LIMA as a bypass graft a consideration. In 98% of the cases the approach to LIMA angiography was femoral with a 5F LIMA catheter first directed into the proximal subclavian and then advanced over a guidewire placed into the distal subclavian well beyond the origin of the LIMA. After withdrawing the wire the catheter was brought proximally to selectively cannulate and visualize the LIMA with nonionic contrast media. The only complication was a single transient occipital visual field loss. LIMA caliber too narrow to permit use as a graft was found twice, LIMA occlusion unrelated to prior surgery was found once, and LIMA occlusion related to prior surgery was found twice. Subclavian and/or vertebral stenosis was present five times. Large proximal branches of the LIMA best identified prior to surgery were present 12 times. Based on this experience, LIMA angiography 1) can be performed safely with a high degree of success, 2) demonstrates significant findings in 15% of cases, and 3) should therefore be performed whenever coronary angiographic findings make it appropriate to consider LIMA to coronary artery bypass grafting.
The antihypertensive and haemodynamic effects of labetalol were compared with those of prazosin both at rest and during bicycle exercise in 38 moderate to moderately severe hypertensive patients (supine DBP 95 to 119 mmHg when untreated). Following a two week open placebo phase to establish baseline BP and baseline exercise performance, patients were randomly and double-blindedly assigned to receive labetalol or prazosin. Drug dose was titrated from 100 to 400 mg labetalol twice daily, or from one to 10 mg prazosin twice daily at weekly intervals until BP was controlled (supine DBP less than or equal to 90 mmHg with at least a 10 mmHg decrease from baseline). Eighteen labetalol and twenty prazosin patients achieved BP control and were subsequently reexercised to fatigue on a bicycle ergometer. The mean changes from baseline for heart rate and rate pressure product (heart rate x SBP) were reduced only in the labetalol group; the difference between the labetalol and prazosin groups was significant (P less than 0.01) both at rest and during exercise. This haemodynamic profile of labetalol may be important in selecting a vasodilating antihypertensive for patients with concomitant ischaemic heart disease.
Three cases of complete heart block complicating retrograde left heart catheterization are presented. In two of the three cases, electrophysiologic study documented block below the AV (atrial ventricular) node. In the third recurrent complete heart block was fatal. It appears that complete heart block complicating retrograde left sided cardiac catheterization is not simply a pericatheterization event; rather, it appears that there is high risk of recurrent complete heart block and that electrophysiologic study is mandatory.
A 32-year-old man presented with symptoms and electrocardiographic changes consistent with acute anterolateral myocardial infarction. Selective coronary angiography revealed thromboses in the infarct related artery as well as in the right coronary artery. This case is unique because bilateral in-situ coronary thrombosis producing acute myocardial infarction was documented in the absence of previously proposed mechanisms.
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A case of arterial sheath kinking is reported. Radiographically, sheath kinking has some features which mimic sheath fracture. The radiographic appearance of sheath kinking is, however, distinctive and clearly separable from sheath fracture, the hallmark of which is extravasation of contrast at the fracture site.
Maximal exercise capacity after control of resting blood pressure with labetalol was studied in nine hypertensive men aged 34 to 69 years (average 52 years). Subjects exercised to exhaustion on an upright cycle ergometer with workload increased as a step function by 25 watts every three minutes, both before and after control of blood pressure was obtained. Mean exercise capacity expressed as total time of exercise until exhaustion was 936 seconds prior to control of the resting blood pressure and 884 seconds (no significant difference) after control of resting blood pressure with labetalol. Double product at peak exercise fell from 254 X 10(2) mm Hg beats per minute prior to blood pressure control to 183 X 10(2) mm Hg beats per minute (p = 0.006) after control of blood pressure with labetalol. The difference in the means of resting heart rate and both peak blood pressure and peak heart rate with exercise were all statistically significant after control of blood pressure with labetalol. These findings suggest that labetalol has an ideal exercise profile affording a cardioprotective effect by decreasing double product but without sacrificing exercise capacity.
As with all skilled techniques, there is a learning curve for percutaneous coronary angioplasty. This curve has been well described in the literature and it is generally quoted that an initial success rate of 70 to 75 percent in reaching and crossing lesions is to be expected during the first 20 cases. However, the introduction of the steerable or guidewire-directed dilation catheter has altered the learning curve. After an initial experience of six nonsteerable percutaneous transluminal coronary angioplasty procedures, 20 consecutive steerable percutaneous transluminal coronary angioplasty procedures were performed without a single failure to reach or cross a lesion. These 20 consecutive steerable coronary angioplasty procedures included eight single left anterior descending lesions, two double (lesions located in series) left anterior descending lesions, six single right coronary lesions, one double (lesions located in series) right coronary lesion, and three single circumflex lesions. It is concluded that the introduction of the steerable system for percutaneous transluminal coronary angioplasty has shifted the learning curve, and that skilled and experienced coronary angiographers beginning a coronary angioplasty program can expect an initial success rate in reaching and crossing obstructive coronary lesions far in excess of the figures quoted in the literature. This may have significant implication for the ultimate availability of percutaneous transluminal coronary angioplasty to patients with coronary artery disease.
A case of catheter-induced proximal dissection of an angiographically normal left coronary artery is reported. Dissection was not associated with pressure damping and myocardial ischemia was delayed until 1 hour after dissection occurred. Prompt recognition of this entity is essential as emergency revascularization is the treatment of choice when significant amounts of myocardium are threatened.
The location of obstructive coronary artery lesions in single-vessel disease is nonrandom. The circumflex coronary artery is protected relative to the right coronary artery. This may have important implications regarding the causation of coronary obstructive lesions.
A 44-year-old man developed recurrent pulmonary embolization after implantation of a permanent transvenous DVI pacemaker connected to polyurethane leads. Thrombus was found in the left innominate and subclavian veins around the pacemaker leads, but not in the right atrium or in the venous system of the pelvis and the lower extremities. The recurrence of pulmonary embolization followed discontinuation of treatment with Coumadin. This case demonstrates that lifelong anticoagulation is indicated in patients who have had pulmonary embolization and/or venous thrombosis around the pacemaker leads.
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Complete fracture and separation of a right coronary Judkins catheter during coronary angiography is presented. The possible mechanism underlying the separation and retrieval of the catheter fragment is described.
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