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Biomedical subjects

A Figueira Moure

Publications and source records attributed to A Figueira Moure.

9 recordsLinked to original sources

[Early extubation with caudal morphine after pediatric heart surgery].

OBJECTIVES: To analyze the viability of immediate extubation of children after corrective surgery for congenital heart defects with extracorporeal membrane oxygenation using an anesthetic technique involving caudal morphine, and to study the effect on length of stay in the pediatric intensive care unit (PICU) or elsewhere in the hospital. MATERIAL AND METHODS: Twenty-nine ASA I-II patients without coagulation alterations undergoing surgery to correct simple heart defects were selected for extubation after surgery. Anesthesia was provided with with sevoflurane, midazolam, rocuronium, fentanil (maximum dose 10 micrograms/Kg) and a bolus of caudal morphine (50-60 micrograms/Kg) after anesthetic induction. Patient characteristics, type of surgery, times of extracorporeal circulation and of ischemia, arterial blood gases upon arrival in the PICU, postoperative complications and quality of analgesia were the variables analyzed. We also compared length of stay in the PICU and hospital for the study group and for a historical control group of 23 patients who had no received caudal morphine or been selected for early extubation. RESULTS: All patients were extubated satisfactorily in the operating room. None required reintubation or reoperation. Postoperative pain was controlled with metamizol alone for 79.3%. No episodes of respiratory depression or neurological complications were observed. PICU and hospital stays were significantly shorter in the study group than in the control group. CONCLUSIONS: Of patients undergoing simple corrective heart surgery with extracorporeal membrane oxygenation immediate extubation did not increase postoperative morbimortality and shortened the hospital stay. A single dose of caudal morphine provided optimum conditions for extubation and good control of postoperative pain. Strict measures must be taken, however, to avoid postpuncture bleeding.

Analgesics, Non-Narcotic↗

[Hypertriglyceridemic pancreatitis and pregnancy].

A 33-year-old secundipara with a history of gestational diabetes and familial hypertriglyceridemia exacerbated during her previous pregnancy was admitted in the 36th week of gestation with diffuse abdominal pain, vomiting, low-grade fever, and general malaise. A blood sample had a lipemic, milky-pink appearance and plasma concentrations were as follows: triglycerides 2173 mg/dL, cholesterol 320 mg/dL, amylase 801 U/L, lactate dehydrogenase 650 U/L, creatinine 1.5 mg/dL, glucose 380 mg/dL, and left-shifted white cells. Acute pancreatitis was diagnosed and owing to signs of fetal distress, a cesarean was performed under light general anesthesia with propofol, succinylcholine, and sevoflurane. After the umbilical cord was cut, rocoronium and fentanyl were administered. The neonate was healthy and the patient's condition evolved favorably with conservative treatment. The incidence of pancreatitis during pregnancy is low but related morbidity and mortality are high. The usual cause is biliary tract disease, although rare metabolic alterations such as hyperlipidemia may occasionally act as the trigger. Early diagnosis and treatment are the keys to successful surgery and postoperative recovery.

Adult↗

Original articles published in Revista Española de Enfermedades Digestivas (1993-1998): authorship, interval between acceptance and publication, and bibliographic references.

AIM: To study changes in authorship, interval between acceptance and publication, and bibliographic references of original articles published in Revista Española de Enfermedades Digestivas (REED) between 1993 and 1998. METHODS: This was a descriptive retrospective study of 359 original research articles published in REED between 1993 and 1998. The variables assessed were: number of authors (author/article index), interval between acceptance of the manuscript and publication in the journal, and degree of obsolescence of articles based on the age of the references cited (Burton-Kleber and Price indexes). RESULTS: The author/article index was 6.1, and increased from 5.9 in 1993 to 6.5 in 1998. The interval between acceptance and publication increased from 251 days to 436 days in this period (p < 0.0001). English was the language of publication used most commonly, followed by Spanish (10.7%). Citations to Spanish references decreased from 12.5% in 1993 to 8.7% in 1998. The half-life of articles was 7 years, and Price index was 41.5%. CONCLUSIONS: REED's bibliometric characteristics are similar to those of other national journals, but this study shows changes in bibliographic indicators from 1993 to 1998; increases in the number of authors per article, the interval to publication, the use of foreign references and the degree of obsolescence.

Authorship↗

[Carotid endarterectomy: postoperative morbimortality and requirements for intensive care].

OBJECTIVES: To analyze risk factors, morbidity and mortality of carotid endarterectomy, and to determine whether prolonged attention in the postoperative intensive care recovery unit is needed by all patients. PATIENTS AND METHODS: A retrospective study of 102 carotid endarterectomy patients between January 1991 and February 1997. The following data were analyzed: preoperative risk factors, prior neurologic symptoms, time of stay in the recovery unit, postoperative complications requiring intensive treatment and the time of onset of such events, and mortality after 30 days. RESULTS: Some type of postoperative complication developed in 35% of patients in the recovery unit, requiring specialized medical attention; 94.8% occurred within eight hours of admission to the unit and the most common complication was hypertension. After transfer to the ward, 9 more patients (8.8%) suffered severe complications, most commonly coronary ischemia. Mortality was 1.9% and the combined rate of mortality plus severe neurologic event was 2.9%. Preoperative hypertension and the presence of more than three risk factors in the same patient was statistically related to the development of postoperative complications. Presurgical coronary disease was related to postoperative ischemic complications. CONCLUSIONS: Patients undergoing carotid endarterectomy with fewer than four risk factors and no ischemic heart disease or severe hypertension can probably be transferred to the hospital ward eight hours after admission to the recovery unit if no complications have developed, thus reducing hospital costs. We believe that appropriate vigilance of such patients should then be provided on the ward.

Critical Care↗