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Biomedical subjects

A Filipowicz

Publications and source records attributed to A Filipowicz.

27 records · Page 2Linked to original sources
PubMedDate not supplied

[Coexistence of idiopathic spontaneous nocturnal enuresis and migraine in children].

In a 7-year prospective follow-up of 104 children with enuresis in 32 cases (19 boys and 13 girls) coexistence of common migraine was found. Twenty-two children had various other seizure-like disorders, particularly tics, febrile convulsions, pavor nocturnus and fainting, and three had absence attacks. In 20 cases vasomotor disturbances and in 17 abnormal Schellong's test were found. The IQ was normal or high in all cases. Emotional disorders were observed in nearly half the cases. The water-salt test of Decourt was done in 9 cases and it was abnormal in 8 cases. At least two abnormal EEG records were obtained in 26 cases, and in 24 of them seizure activity was demonstrated in the EEG. In the period of follow-up disappearance or very marked improvement of enuresis occurred in all cases and migrainous attacks became less frequent and intense in 27 cases, while in 5 the severity of migraine increased. The author discusses the pathological mechanism of these disturbances calling attention to less good efficiency of the regulatory functions of the centrencephalic activating system and hypothalamus connected with biochemical and bioelectric immaturity.

Adolescent↗
PubMedDate not supplied

[Basilar migraine in children].

The authors describe 3 children aged 12-15 years with severe basilar artery migraine. The follow-up was 2-3 years. In all cases attacks of throbbing headache occurred which showed varying intensity and lateralization in 2 cases. Only one child had always very strong right-sided headaches. The accompanying symptoms and signs were mostly from the area of vascularization of the basilar artery. In one child attacks of unconsciousness occurred additionally. The authors suggest that the symptoms and signs from brain-stem structures associated with attacks of headache may be due not only to construction of the basilar artery but may be due to a steal effect from certain regions of the brain stem in the phase of vasodilation, although the primary haemodynamic disturbance may not necessarily develop within the basilar artery system.

Child↗
PubMedDate not supplied

[Humoral immunological reactivity in subacute sclerosing panencephalitis].

In a group of 37 children with SSPE serum protein and cerebrospinal fluid electrophoresis was done (in 34 and 25 cases respectively) determining immunoglobulins in the serum and cerebrospinal fluid in all 37 cases. The obtained results demonstrated a lack of correlation between the changes observed in the serum and cerebrospinal fluid. The most frequent change in the serum was a rise in alpha 2 globulin level (85%) and reduced IgA level (58%), while in the cerebrospinal fluid a rise in gamma globulins (92% of cases) and IgG (100%) was observed most frequently. A comparison of these results with past history of measles, with the clinical course of SSPE and with the survival time of the children showed no correlations. Measles antibodies were determined in the serum and cerebrospinal fluid in 37 children, and the determinations, were repeated several times in the serum of all children and in the cerebrospinal fluid of 9 children. Measles antibodies were found in the serum in all children and in the cerebrospinal fluid in 21 children (57%). The highest titres of antibodies above 1:32 in the cerebrospinal fluid were demonstrated in children with measles at the age up to 2 years. The prognosis was worst in children with acute onset of the disease preceded frequently by cranial injury or infection, with a high serum antibody level and absence of antibody in the cerebrospinal fluid.

Antibodies, Viral↗
PubMedDate not supplied

[Case of a particularly severe migraine in a boy].

An unusually severe and uncommon clinical syndrome of migraine with complications in a boy treated during 9 years is described. Severe attacks of migraine were associated with changing cerebral function defects, prolonged disturbances of consciousness, and significant symptoms of intracranial hypertension. Vertebral angiography demonstrated disturbances in cerebral circulation.

Age Factors↗
PubMedDate not supplied

[Effect of infections on the course and effectiveness of epilepsy treatment in children].

The analysis was carried out in a group of 32 children with coexistent chronic urinary tract or respiratory infections. In 20 children an unfavourable effect of infection on the course of epilepsy was observed. Worsening of epilepsy during infection was observed mainly in children without evidence of nervous system damage with primarily generalized seizures, and in cases when the first attacks developed after protective vaccinations. The effect of urinary tract infections was particularly unfavourable. The authors put forward the hypothesis of immunological basis of exacerbation of epileptic seizures during chronic infections.

Adolescent↗