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Biomedical subjects

A Fourrier

Publications and source records attributed to A Fourrier.

At least 19 recordsLinked to original sources

[2d-generation cephalosporins in the treatment of gram-negative superinfections].

The second generation cephalosporins are those drugs that are totally or partially resistant to betalactamases (cefamandole, cefuroxime) or the cephamycins (cefoxitine). This property allows them to destroy the enterobacteria resistant to cefalotine and they may have a place in the treatment of certain post-operative infections (abdominal, gynaecological, urinary) on their own or in combination with an aminoglycoside. They also may be of use in combination with an aminoglycoside in the management of secondary septicaemia infections. Outside of these indications which are dependent on the bacteriological findings, their use should be limited even when there is an absence of organisms that are Cefalotine sensitive on the antibiogram. This careful approach (which applies particularly for cefotaxine) may be abandoned once a certain quantity of resistant strains have emerged. For the time being, the second generation cephalosporins ought to be used only for specific indications, and as a general rule should not be first line antibiotic treatment.

Cephalosporins

[Current place of the Pneumococcus in infectious pathology].

This work regroups an important number of acute pneumococcal infections with septicemia, which recalls that these infections are of current importance, owing to their frequency and poor prognosis. Present diagnositc, clinical, radiological and bacteriological methods are discussed and criticised. An important, but not exclusive place, is reserved for routine blood culture. Finally, the authors discuss future prospects of acute pneumococcal infections, mainly diagnostic and prophylactic.

Acute Disease

[Study of 52 cases of diphtheria observed over a period of ten years in the North of France (author's transl)].

Over a period of ten years, 88 cases of diphtheria were diagnosed in the North of France especially in the area of Lille, Roubaix and Tourcoing. 25 p. cent of the patients had been correctly vaccinated within less than five years, and among the latter 25 p. cent died from their diphtheria. The clinical presentation was typical but delay in diagnosis is frequent.

Adolescent