Biomedical subjects
Publications and source records attributed to A Francone.
The authors report a case of mesenteric liposarcomas in a 70-year-old patient, describing the instrumental diagnostic procedure in order to show the importance of Computed Tomography (CT) in the diagnosis of this tumor.
Celiac disease (CD) is the most common form of malabsorption in childhood when it presents with diarrhea and growth failure, a jejunal biopsy is considered the first diagnostic investigation by some authors. In adulthood, clinical symptoms of CD may mimic several different disease, such as peptic ulcer and IBS, and the first diagnostic investigation is an upper GI series. Radiological features of duodenum and small bowel were evaluated in twenty patients with adult onset celiac disease. Sign of duodenitis such as thickened folds, mucosal nodules, dilatation of duodenum and erosions were observed in 19 out of our 20 patients (95%); particularly, thickened folds in 17 (85%), nodularity in 16 (80%), duodenal dilatation in 12 (60%) and erosions in 4 (20%). In celiac disease the lesions are more severe in the upper part of small bowel, and duodenitis may be the unique sign of CD. Duodenitis may be part of a disease involving the entire small bowel; so, a duodenitis observed in the upper gastrointestinal tract requires the study of the entire small bowel--which seems to be very important in the case of celiac disease.
Hibernoma is a rare hypervascular benign tumour that originate from brown fat. A case of hibernoma of the thigh, examined by xeroradiography, ultrasound, CT and angiography, is reported. The characteristics of this tumour are considered.
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A high incidence of empty sella was found, by CT.HR and MR, in 18 patients with congenital hypothyroidism studied by plain skull radiographs, hormonal and radioimmunoassays and scintiscan. From a pathogenetic point of view, it is interesting to note that all patients had been given inadequate therapy for a long period. A significant incidence of cerebral atrophy was found in young congenital hypothyroid subjects. Radiographic examination is still useful, mainly in the screening of these lesions. In fact, morphologic and/or volumetric alterations of the sella, corresponded in all cases to the finding of an empty sella, as demonstrated by CT.HR and MR. Both these techniques have a high diagnostic accuracy in identifying the lesion. The contribution of imaging techniques is even greater in view of the fact that the clinical and biohumoral picture of empty sella is still ill-defined.