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Biomedical subjects

A Frangos

Publications and source records attributed to A Frangos.

8 recordsLinked to original sources
PubMed1984

Peripheral venous pulsatility detected by Doppler method for diagnosis of right heart failure.

This study shows that peripheral venous flow detected by Doppler ultrasound becomes synchronously pulsatile with heart beats as soon as central venous pressure (CVP) is above 7 mm Hg. CVP was above 7 mm Hg in 13 among 46 patients. Clinical signs of right heart failure were detectable in only 7 of these 13 patients (sensitivity 54%), whereas peripheral venous flow was pulsatile in 12 of them (sensitivity 92%). In 4 patients with a normal CVP, peripheral venous flow was also pulsatile; all of them suffered from valvular heart disease with left ventricle ejection fraction below 60% in 3 of them. The detection of a pulsative peripheral venous blood flow constitutes an early sign of right heart failure, more sensitive than clinical evaluation, and probably even more than CVP.

Central Venous Pressure↗
PubMedDate not supplied

Diastolic mitral gradient without associated valvular stenosis: usefulness of two-dimensional echocardiography for a correct diagnosis.

A diastolic gradient across the mitral valve is generally indicative of mitral valve stenosis. In the present study, echocardiography was used to demonstrate two less common causes of left ventricular inflow obstruction: one patient had a fibromuscular membrane beneath the valve, the other a large vegetation attached to the posterior leaflet of the mitral valve. Echocardiography proved to be the optimal imaging technique in each case.

Adult↗
PubMedDate not supplied

Acute hemodynamic effects of intravenous amiodarone in patients with coronary artery disease.

The acute hemodynamic effects of intravenous amiodarone (Cordarone injectable; Labaz) were studied during cardiac catheterization in 16 male patients with coronary artery disease (age range, 38-64 years; mean, 53 years). Amiodarone was administered as a bolus at a dosage of 5 mg/kg bodyweight over a 1-min period. Measurements were made 5, 10, and 15 min thereafter. The drug had little effect on heart rate, aortic pressure, cardiac index, and vascular resistances. There were small and nonsignificant increases in left ventricular end-diastolic pressure and end-diastolic volume. The ejection fraction decreased slightly and not significantly. In addition to some increases in pulmonary wedge, pulmonary artery, and right atrial pressures, the significant findings were a 15% decrease in maximal dP/dt and a 12% decrease in left ventricular work. These changes point to a slight negative inotropic effect of amiodarone.

Adult↗