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Biomedical subjects

A Freiberg

Publications and source records attributed to A Freiberg.

At least 37 records · Page 2Linked to original sources
PubMed1992

Investigation of spatial relationships and energy transfer between complexes B800-850 and B890-RC from Chromatium minutissimum reconstituted into liposomes.

Spatial relationships between different pigment-protein complexes in the membranes of the purple photosynthetic bacterium, Chromatium minutissimum, have been studied. The possibility of restoring the function of efficient excitation energy transfer from bacteriochlorophyll molecules to the reaction centers in the system of soybean liposomes, reconstituted with pigment-protein complexes B800-850 and B890-RC from C. minutissimum, has been explored. The chemical cross-linking method, together with stationary and picosecond spectrally resolved fluorescence measurements were employed. It has been shown that after the incorporation of the complexes into the liposome membranes conditions for directed excitation energy transfer from the light-harvesting pigments to the reaction centers are created, which are less optimal, however, than those in the native state. Possible reasons are considered.

Bacterial Proteins↗
PubMed1992

Is breast feeding possible after reduction mammaplasty?

The purpose of this study was (1) to evaluate the frequency of breast feeding in patients who had given birth following reduction mammaplasty using an inferiorly based pedicle flap and (2) to identify operative and nonoperative factors that may affect breast feeding following reduction mammaplasty. Seventy-three patients between the ages of 18 and 40 years were contacted and sent a standardized questionnaire. Data collected included age at pregnancy, duration of breast feeding, difficulties while breast feeding, and reasons for discontinuing breast feeding. A total of 20 patients of the 68 who responded had become pregnant following reduction mammaplasty. All 20 women lactated. Seven of these women (35 percent) went on to a breast-feed successfully, whereas 13 (65 percent) decided not to breast-feed or discontinued breast feeding for a variety of personal reasons.

Adolescent↗
PubMed1991

A critical look at abdominal lipectomy following morbid obesity surgery.

This article reviews a series of 26 consecutive nonaesthetic post-morbid-obesity weight loss patients undergoing abdominal lipectomy. Patient satisfaction was assessed by a questionnaire. All patients obtained symptomatic relief but surprisingly most had expected to look better following surgery, indicating the importance of discussing this aspect preoperatively. Technical modifications to remedy some of these problems are discussed.

Adult↗
PubMed1990

Radial artery infections and aneurysms after catheterization.

Twelve patients in whom radial artery infections developed after catheterization in an intensive care unit over a 2-year period were reviewed. The incidence of local infection was 0.4%. An increased risk of infection was associated with prolonged catheterization (greater than 4 days). Aneurysms developed in five patients. Signs of septic emboli were present in two patients, including Osler's nodes, Janeway's lesions, and fingertip infarcts. In 6 of the 12 patients, the radial artery infection resolved with antibiotic treatment alone. The five patients with infected aneurysms were treated successfully with antibiotics and surgical excision. The radial artery was reconstructed by use of a vein graft in one patient. We believe that patients not responding promptly to antibiotics or patients with infected aneurysms are best treated by surgical excision.

Adolescent↗
PubMed1989

Nonoperative treatment of trigger fingers and thumbs.

This article reports our experience with the management of 93 consecutive patients with 108 trigger digits initially treated by triamcinolone acetonide injections into the flexor tendon sheath. It appears that two distinct clinical types of trigger digits exist--nodular and diffuse. Ninety-three percent (63/68) success was obtained in the nodular type compared with 48% (10/33) in the diffuse type (p less than 0.05). We conclude that the patients with the nodular type should be offered a simple cortisone injection. Those patients seen initially with the diffuse type should probably be offered surgical decompression.

Adult↗
PubMed1989

Challenges in developing resident training in aesthetic surgery.

Adequate resident training in aesthetic surgery has been a problem and challenge for program directors in the past. In a 1982 survey of 11 former University of Toronto residents, 4 residents identified this part of their training as adequate, and 7 believed it was inadequate. To solve this problem, an Academic Aesthetic Surgery Service was established in one of the University of Toronto participating teaching hospitals (Toronto Western Hospital) in early 1986. This article outlines the organization and function of this service and reports the experience of the first year of operation. The preliminary results are encouraging; the service has been accepted by the patients, residents, and the plastic surgery community.

Curriculum↗
PubMed1989

Normolipidemic xanthomata of the hand extensor tendons.

A 48-year-old man presented with soft tissue lumps over the metacarpophalangeal joints of the long and index fingers of his left hand due to tendon xanthomas. His personal history and laboratory investigations were negative for familial hyperlipidemia or other medical conditions. A simple debulking procedure produced a good cosmetic and functional result at 7 years' followup.

Finger Joint↗
PubMed1988

Aneurysm of a common digital artery: case report and literature review.

The authors' recent experience of a 46-year-old woman with an aneurysm of a common digital artery led them to review the appropriate treatment for this rare condition. They found only one other reported case. In most reports on aneurysms of hand vessels, the aneurysm is of traumatic origin, but this was not the case in their patient. For such a rare condition, the authors emphasize the need for acute awareness of its possibility, angiography to evaluate the collateral circulation and early excision to relieve symptoms and avoid neurologic damage.

Aneurysm↗
PubMed1987

Apple-coring technique for severe gynecomastia.

In evaluating cases of gynecomastia it is important to differentiate between physiologic and pathologic forms. The authors review gynecomastia with reference to its occurrence in various age groups, the pathologic features and etiology, and the differentiation and classification of the two types. If the gynecomastia is large or longstanding, surgical treatment may be necessary. The authors review the various surgical techniques used from the early descriptions up to the present. The apple-coring technique has the advantages of leaving an inconspicuous scar, allowing correction of the hypertrophic areola and good chest-wall contour, maintaining the viability of the nipple and decreasing the common complications of inverted nipples and a doughnut-shaped deformity. The results and outcome in four patients treated by the apple-coring technique are reported. Although the method is not perfect, the results are encouraging and the technique is an addition to the armamentarium of surgeons treating large gynecomastia.

Adolescent↗
PubMed1986

Reduction mammaplasty: a comparison between the Robbins and Pontes techniques.

The purpose of this paper is to propose a practical classification of mammary hypertrophy and compare perioperative factors in two types of reduction mammaplasty: the Pontes and Robbins techniques. In a series of 51 patients, the advantages and disadvantages of each method are compared and discussed. The Pontes method appears to be better for the low-volume and ptotic (type II and III) breast, whereas the Robbins technique has a more universal application.

Breast↗
PubMed1980

Two-team approach to surgery for head and neck cancer.

The authors describe a 10-year experience with the two-team approach to complex operations for head and neck cancer. The general surgical team is responsible for the excision of the lesion and the plastic surgical team for the reconstruction. Twenty-seven patients have been treated in this way. A brief history, a general outline of overall management, the approach to oral, pharyngeal and extrinsic laryngeal lesions and the methods of reconstruction are described. The advantages and disadvantages of the method are presented. This approach has been found beneficial to the patients and satisfactory to the two surgical teams. In the opinion of the authors the advantages of this approach outweigh the disadvantages.

Head and Neck Neoplasms↗