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Biomedical subjects

A Fuhrmann

Publications and source records attributed to A Fuhrmann.

12 recordsLinked to original sources
PubMed1991

[The regenerative capability of the condylar process of the mandible].

In a roentgenographic follow-up study in children with 139 fractures of the condylar process of the lower jaw the following observations were made: A restitutio ad integrum was achieved with conservative measures in all of the non-displaced fractures, in most of the displaced fractures, and in less than 50% of the fracture dislocations. The best results were seen in children under the age of 10 years.

Adolescent↗
PubMed1990

Regulation of the human autologous T cell proliferation by endogenously generated C5a.

The immunomodulating role of endogenously synthesized C5 and subsequently generated C5a was studied in a serum-free human autologous mixed leukocyte reaction (AMLR) using either separated T and non-T cell populations or unfractionated mononuclear leukocytes of human peripheral blood. Monoclonal mouse IgG or Fab fragments against human C5/C5a were used as probes for the evaluation of the biological effects of C5a. The reduction of DNA synthesis after the addition of nanogram amounts of anti-C5/C5a mAb was dose-dependent, reaching maximum levels of 30-50%. Of special importance was the availability of a mAb that recognizes a neoepitope present on C5a and not on serum-derived C5. The demonstration of the specificity of its inhibitory effect suggests that C5 is synthesized under the in vitro conditions employed and that the subsequently generated C5a exerts biological effects on T cell proliferation.

Antibodies, Monoclonal↗
PubMed1987

The double-headed mandibular condyle.

The double-headed condylar process is rare. Radiographs of four patients with this type of anomaly and one skeletal specimen are described in this article. Histologic studies in rodents suggest a possible mode of pathogenesis: maldirected muscular pull may lead to the development of an extra mandibular capitulum.

Adult↗