Biomedical subjects
Publications and source records attributed to A Fujimoto.
This article reports a rare case of pigmented villonodular synovitis (PVS) arising from the plica synovialis mediopatellaris that impeded the knee joint when it was extended. This lesion was diagnosed and treated by arthroscopy.
Four human female fibroblast strains with an i(Xq) or derivative X chromosome as a cytological marker for the inactive X chromosome were used to determine the frequency of sister chromatid exchanges (SCEs) in the active and inactive X chromosomes. No significant difference in SCE frequency between the active and inactive X chromosomes was observed. Therefore, the state of chromatin condensation and the late DNA replication in the facultative heterochromatin of the inactive X chromosome do not appear to influence the SCE frequency.
This paper represent one of the important index of gingival color to various conditions. Generally the gingival color is very difficult problem to measure, so experimental gingivitis has to be treated by special technique such as Discriminant Analysis in spectrum pattern analysing. On measuring gingiva, Standard Measuring System is used in our department. Tissue Spectrum Analyzer TS-200 is used for measuring gingival color and spectrum pattern. Spectrum patterns are classified by its strength into three categories, that is Normal, Slightly-Redness and Redness. Discriminant Analysis and Graph Analysis (Constellation Graph) showed each group of property. The following results were obtained; Spectrum patterns have two peaks, that is 542 nm and 577 nm. With gingivitis change on three steps, that is Normal, Slightly-Redness and Redness, spectrum powers and difference of absorption in spectrum degrees and brightness is down. With gingivitis change, the Z1 value was obtained by Discriminant Analysis and showed a tendency to sign change from minus to plus. In the result of Discriminant Analysis distinction rate is 97.4% in N Group, 98.5% in SR Group and 100% in R Group. Constellation Graph represented each group of property clearly.
Using 125I-EGF the distribution of EGF receptors in psoriatic epidermis was autoradiographically examined. Binding sites of 125I-EGF (20 ng/ml) were mainly located at basal and suprabasal cells in normal and uninvolved psoriatic epidermis, whereas they were located at spinous cells as well as at basal and suprabasal cells in affected psoriatic epidermis. Binding of 125I-EGF (1 ng/ml), on the other hand, was observed in normal and uninvolved psoriatic epidermis but not in affected psoriatic epidermis. The majority of EGF receptors in affected psoriatic epidermis were featured by low affinity for EGF.
The interrelationship between tooth forms and facial outlines is represented in multivariate linear combinations. Principal Component Analysis was used in this study as an expression of morphological features. Measured data on the tooth and the face could be classified into 4 types by the first and second principal components of multivariate analysis. Of the 117 subjects, the largest group of 33 (28.9%) had of oval faces and were Class III for the face and Class II for the teeth, respectively. Of the 117 subjects, 36 showed morphological similarity between teeth and face.
We studied the possibility of estimating the root surface area from measurements of various points on extracted teeth using multiple regression analysis, and found that this method might be applied clinically.
Variation of DA/DAPI intensity in the Yq12 band was observed in five amniotic cell specimens and one blood specimen from the father of one fetus. Three distinct classes of Yq heterochromatin were identified by distamycin A (DA) treatment of the cell cultures and various staining techniques. The heterochromatin in the Yq11.23 sub-band does not undercondense when exposed to DA, and shows pale fluorescence with quinacrine staining, positive C-banding, and bright fluorescence with DA/DAPI technique. This class of heterochromatin was consistently observed in all specimens studied. The other two classes of heterochromatin are in the Yq12 band. Both show undercondensation when exposed to DA, quinacrine-bright fluorescence, and positive C-banding; however, one class of heterochromatin shows DA/DAPI-bright fluorescence and the other shows pale fluorescence. The size and banding intensity of the two classes of heterochromatin in Yq12 are variable. These results provide cytological evidence of heterogeneity within the Y heterochromatin region containing AT-rich DNA.
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We observed an autosomal dominant disorder of abnormal upper lip, which resembles a poorly repaired cleft lip, malformed nose with broad bridge and flattened tip, lacrimal duct obstruction, malformed ears, and branchial cleft sinuses and/or linear skin lesions behind the ears in several persons in 3 families. In each of the 3 families, an affected parent had at least one affected child. Father-to-son transmission in one of these families ruled out X-linked inheritance. Other anomalies include coloboma, microphthalmia, auricular pits, lip pits, highly arched plate, dental anomalies, and subcutaneous cysts of the scalp. Premature graying of hair occurred in the affected adults. Growth retardation, developmental delay, and hand anomalies are variable components of the syndrome.
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