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Biomedical subjects

A Furdová

Publications and source records attributed to A Furdová.

18 recordsLinked to original sources
PubMed2003

[Carcinoma of the eyelid arising from a Meibomian gland].

UNLABELLED: Carcinoma of the Meibomian gland of the eyelid is very rare with atypical glandular features, that may appear initially as a chalazion formation and then invades the neighbouring tissues. PURPOSE: Demonstration of the importance of surgical excision and histological examination in presence of an apparently harmless tumoral alteration of the eyelids and verifying every case of atypical lesion of the eyelid region. Case presentation No. 1: We report a case of 76-year old woman patients suffering from chronical blepharoconjunctivitis and chronical chalazion many times simply performed excochleation. Histopathological finding of the excision of the tumour showed the presence of carcinoma Meibomian gland (stage G2), the patient refused exenteration and died in 2 month interval. Case presentation No. 2.: 65-year old men with carcinoma linguae 1.sin. (T3 N2 M0) in 1998 after hemiglossectomia, resectionem baseos oris 1.sin. and radiotherapy, came to our clinic with exoftalm and tumor in his right orbit in Jun 2001. CT found tumour 3 x 2 x 2 cm. In September 2001 orbitotomia bicoronalis 1.sin., extirpatio TU orbitae 1.sin. histologically verified karcinoma of Meibomain gland, patient without any problems after operation and radiotherapy.

Aged↗
PubMed2003

[Initial experience with the EAS-1000 (NIDEK) anterior segment analyzer].

The analyzer of anterior segment EAS-1000 is one of recently developed diagnostic devices, used for digital photography for the analysis and storage of data about the anterior segment of the eye. The aim of the contribution is to inform the public about possible use of the apparatus in clinical and field practice.

Anterior Eye Segment↗
PubMed2001

[Peroperative use of mitomycin C in excision of primary pterygia].

The authors in a retrospective study assess the recurrence rate of pterygium after the application of a single intraoperative dosage of topical Mitomycin C during the pterygium excision. The group involves 21 eyes of 19 patients with primary pterygia. When using technique of simple pterygium excision followed by application 0.02% MMC onto a bare sclera in duration 3 minutes, pterygium recurred in 5 patients (23.8%). The authors noticed a distinct difference in pterygium recurrence relating to the age of patients. Under the age 50 the recurrence occurred in each of 4 patients, above the age 50 only in one out of 17 patients (5.9%).

Adult↗
PubMed2000

[The TNM classification system in malignant conjunctival neoplasms].

The authors submit a review of histological findings and classification according to the TNM-classification of conjunctival tumours in patients under dispensary care at the First Ophthalmological Clinic of the Faculty Hospital and Medical Clinic of the Comenius University in Bratislava during a 10-year period (1989-1998). They included in the group 75 patients with clinically assessed conjunctival tumours (0.4% of the hospitalized patients). As to histological findings, 61 times (80.3%) a benign process was involved (naevus of the conjunctiva 12x) and 14x (19.7%) a malignant tumour, (7x times a primary malignant melanoma of the conjunctiva, 3x carcinoma). The authors recorded two relapses (one malignant melanoma of the conjunctiva, one melanoma penetrating into the orbit). The mean age of the patients was 47 years (from 1 to 82 years). In malignant melanoma of the conjunctiva stage T1 was detected in as many as 3/4 of the patients (6 times), whereby stage pT1, 2 was found in 7 patients. In carcinoma the authors did not detect stage T1, only stage T2 in 2 patients, T3 (pT3) in one patient.

Adolescent↗
PubMed1998

[Use of oncologic markers in ophthalmic oncology].

The authors draw attention to the possible application, and present their initial experience with examination of serum for the presence of oncomarkers (using radioimmunological methods) in clinical practice of ophthalmooncology in a group of 12 patients treated at the First Ophthalmological Clinic, Faculty Hospital Comenius University, Bratislava in 1997. The mean age of the patients was 59 years. In the first sub-group are nine histologically confirmed malignant melanomas of the uvea (eight times after enucleation of the bulbus and once after block-excision combined with application of the beta-emitter Ru106). In the second sub-group are three patients (one female patient with MMU after application of the beta-emitter Ru106 without enucleation and two patients under investigation on account of a naevus of the choroid). In the whole group of 12 patients the following oncomarkers were examined: TK titre, TPA, B2M and NSE and the patients are monitored so far during a one year period of dispensarization. Elevated levels of beta-2-microglobulin (B2M) were recorded in 50% of the patients and elevated levels of the tissue polypeptide antigen (TPA) in 25% (in the group of histologically confirmed malignant melanomas of the uvea). On examination of the other oncomarkers (TK, NSE and FE resp.) no positive results were recorded. The importance of investigation of the mentioned oncomarkers in ophthalmooncology is in particular the possibility of early detection of metastases in patients after termination of treatment on account of a malignant melanoma of the uvea.

Adult↗
PubMed1998

[Ultrasonic diagnosis of retinal detachment after internal tamponade with silicone oil].

The authors evaluate the results of ultrasound examination of 20 patients with retinal detachment (20 eyes) after pars plana vitrectomy with silicone oil tamponade. Ultrasound diagnostic method is necessary in cases with non-transparent optic media. Silicone oil in the space of vitreous cavity has a character of a swimming water-drop and his physical properties can change the echography results. Between the eye-wall and silicone oil is a virtual space, which could be well visualised by ultrasound. The patients are divided into 2 groups. In the 1st group there were 7 eyes with transparent optic media and retina was detached under the silicone oil. By ultrasound the retina detachment echo was localised between the echos of silicone oil and eye wall. In the 2nd group there were 13 eyes with non-transparent optic media. In 6 cases (41.6%) the retinal detachment echo was visualised. The retinal detachment was confirmed by vitreo-retinal surgery.

Adult↗
PubMed1995

[Incidence, geographic distribution, age distribution, mortality and histologic verification of intraocular tumors in the Slovak Republic 1968-1989 (study)].

In the study is given the analysis of the data from National Tumour Registry of Slovak Republic--code 190 (ICD-9) in Slovakia over the period 1968-1989. The paper presents a survey of the incidence of notified malignant intraocular tumours: we notified 976 diseases--in male 528 (54%) and 448 in female (46%). Intraocular tumours were 0.3% of all the registered oncological diseases in Slovakia in male and also in female. A specific incidence in Slovakia was found to be 1,0/100,000 inhabitants in male, and 0.8/100,000 inhabitants in female and the registered data are comparable to those from surrounding countries in Europe. The mortality rate was found over 0.3/100,000 inhabitants. Microscopically verified were over 90% of the intraocular tumours.

Adolescent↗
PubMed1995

[Acute monocytic leukemia simulating clinical manifestations of retrobulbar neuritis].

Lesion of optic disc may appear also with coherence to myeloid leukaemia. Authors introduce a case report of a patient, who found out help of an ophthalmologist with very indefinite difficulties (visual acuity deterioration of her left eye in connection with long-lasting sinusitis). Due to changes in orbit and the optic disc the status was evaluated as retrobulbar neuritis. During the indicated therapy by corticosteroids (Prednison) a steroid gastric ulcer was unfolded. During the additional therapy and after the sternal punction the acute monocytic leukaemia (AML) was diagnosed. On that base the aimed therapy at the Clinic of Haematology was realised. The patient died 27 months since the diagnose of AML was determined.

Adult↗
PubMed1995

[Histologically verified intraocular tumors in the Slovak Republic 1984-1989].

In the study is given the analysis of the data of patients with dg. 190 (ICD-9) from National Oncology Registry in Slovak Republik in period 1984-1989; the number and the portion of histologically identified intraocular tumors in regions of Slovakia; the data were completed by number of patients from registered announcements of decreases. In 6-years period is registered 278 cases; average 46 cases; the incidence was 0,9/100.000 inhabitants. Microscopically identified were 257 cases (92%). The percentage of microscopically verified cases in regions was from 76% to 100%; we didn't mention the difference between men and women. In the last 2 years the rate of microscopically cases was relatively lower than before. The data completed from the registered announcements of decreases (dissection findings) had no influence to increase the proportion of microscopically identified cases.

Cytodiagnosis↗
PubMed1995

[Survival in patients with malignant melanoma of the uvea].

In the study is given the analysis of the data of patients with malignant uveal melanoma from the tumor register of the Dpt. of Ophthalmology of the Med. Faculty, Comenius University, Bratislava, Slovak republic, in years 1988-1993. In this period there are registered 94 patients with malignant uveal melanoma, 0,86% of all treated patients. There are registered 22 cases (8,2%) in iris, in corpus ciliare 13 (13,8%), in chorioidea - 72 (76,6%). In this 6-years period 74 cases (78,8) were treated by radical surgical techniques (enucleation, block-excision), in 18 cases (19,6%) brachytherapy by episcleral beta-applicator (Ru106/Rh106) was used and 2 of the patients (2,1%) refused any kind of therapy. Follow-up 3 months to 6 years: life expectancy-we didn't mention significant difference in the mortality-rate in the group of 72 patients treated by radical surgical techniques and those (18 cases), who were treated by episcleral applicator (Kruskall-Wallis test). The mortality rate was 25% in group A (enucleation) and 33% in group B (beta-irradiation).

Aged↗
PubMed1994

[Exophthalmus caused by diseases of the lacrimal glands].

In the submitted paper the authors analyze data from a selected patient group with diseases of the orbit and evaluate the ratio of diseases of the lacrimal gland at the First Ophthalmological Clinic Faculty Hospital, Medical Faculty Comenius University in Bratislava between 1980 and 1992. During the mentioned period 25 patients with orbital disease were hospitalized or put on records and dispensarized. Tumours of the lacrimal glands were present 16 times.

Exophthalmos↗
PubMed1994

[Results of treatment of malignant melanoma of the choroid using local beta-irradiation (Ru106/Rh106) from 1988 to 1992].

In the work results of focused, local therapy of the MMU (localised at choroidea) in the years 1988-92, with episclerally fixed applicators of the beta-emittors Ru106/Rh106 are presented. After this, so called "brachytherapy" (without enucleation), the group of 17 eyes (treated 18 times) was evaluated 18-54 months after therapy. Favourable results of treatment of the MMU at choroidea (small and localised) with episcleral, focused beta-radiation are emphasised. Up to December 31, 1992 at the group of 17 eyes healed MMU of the choroidea showed 58.8% of treated patients. Effective visual acuity (between 0.4-1.0) was preserved in 66.6% of the eyes. Exitus due to metastases occurred in 5 patients (24-48 month after therapy) showing the mortality rate 29.4%. These results are comparable with published statistics.

Beta Particles↗
PubMed1994

[Intraocular malignant melanoma in intermediate uveitis treated conservatively and surgically for a prolonged period].

The authors give an account of a 28-year-old female patient treated for a prolonged period in the out-patient department on account of intermediary uveitis with subsequent pars plana vitrectomy of the left eye. After repeatedly deteriorating local findings after a 4-month interval in the punctate of the anterior chamber cells of non-differentiated malignant melanoma were detected; histological examination of the enucleated bulbus confirmed the diagnosis of malignant melanoma penetrating into the optic nerve.

Adult↗
PubMed1994

[Exenteration of the orbit].

The authors evaluate the number and results of exenterations of the orbit on account of malignant neoplasms originating in intraocular structures and penetrating into the orbit or malignant processes originating in structures of the orbital contents and tissues surrounding the orbit. These operations were made in a group of 156 patients with orbital disease hospitalized at the First Ophthalmological Clinic, Faculty Hospital and Medical Faculty, Comenius University, Bratislava in 1980-1992. During the mentioned 13-year period exenteration of the orbit was indicated in 22 patients, i.e. 14.1% from the total number of 156 hospitalized patients with orbital disease.

Aged↗
PubMed1994

[Diseases of the orbit].

In the submitted paper the authors analyze data from a group of patients with diseases of the orbit treated at the First Ophthalmological Clinic, Faculty Hospital, Medical Faculty Comenius University Bratislava between the beginning of 1980 and the end of 1992. During the mentioned period 156 patients with orbital diseases were hospitalized or put on record. The 13-year group of patients is evaluated from the aspect of causes of exophthalmos, age distribution, lateralization of the disease and different diseases by sex. Special attention is paid to a sub-group of 70 patients with tumours of the orbit.

Adolescent↗