PubMed Health⌕ Search

Biomedical subjects

A G Delaney

Publications and source records attributed to A G Delaney.

5 recordsLinked to original sources
PubMed1983

Anesthesia in the pregnant woman.

Obviously, the necessity for surgery and anesthesia during pregnancy has the potential for tragedy in terms of fetal wastage. Modern anesthesia and surgery have overcome the major problems, present at the turn of the century, of maternal morbidity and mortality associated with anesthesia and surgery on the pregnant patient. There is no evidence that a single acute exposure to modern anesthetic agents precludes a successful pregnancy. Aggressive use of modern monitoring techniques for both mother and fetus, together with sensitivity to the very real personal tragedy for the expectant mother who must undergo urgent or emergency surgery, seems to be the best approach for us to take.

Abnormalities, Drug-Induced↗
PubMed1980

The incidence of cholelithiasis after jejunoileal bypass.

In a prospective study of morbid obesity at the University of Florida, 225 consecutive patients with medical complication of obesity underwent intestinal bypass during a ten-year period from 1967 to 1977. The average age was 35 years, with the average weight being 322 lb (145 kg). Oral cholecystograms were obtained preoperatively in all patients, and repeated at one and five years postoperatively. If a patient developed symptoms, ultrasonography or a cholecystogram was performed at that time. The cumulative preoperative prevalence of cholelithiasis was 30.7 percent. The 156 patients with an intact gallbladder made up the study group. These patients have been followed for an average of 36 months, and 16 have subsequently demonstrated cholelithiasis. The post intestinal bypass incidence of cholelithiasis from surgery to the time of their last oral cholecystogram was 7.2 percent per year. Analysis of variance demonstrated no significant differences between patients, with and without cholelithiasis, with respect to serum triglycerides, cholesterol, or percent weight loss. The incidence of cholelithiasis in the morbidly obese increases further with the metabolic derangements induced by jejunoileal bypass. The increased incidence of cholelithiasis after intestinal bypass, along with the other serious metabolic sequelae that follow this procedure, suggests that the continued long-term followup of these patients is mandatory.

Adolescent↗
PubMed1979

Lung transvascular fluid dynamics with extracorporeal membrane oxygenation in unanesthetized lambs.

Extracorporeal membrane oxygenation (ECMO) is used for long-term support of patients with acute respiratory failure. We investigated the effect of partial venoarterial (VA) and venovenous (VV) bypass with filler-free silicone spiral-coil membrane lungs on steady-state lung transcapillary fluid filtration in six unanesthetized lambs for periods of 11 to 32 hours. Using three thoracotomies we prepared animals to collect lung lymph; lymph obtained in this way is representative of lung interstitial fluid. By studying lymph flow and composition we demonstrated that the permeability of the pulmonary capillaries does not change during prolonged partial VV or VA bypass with a membrane lung. There was no accumulation of lung water during bypass, and lung protein and fluid leak neither increased not decreased with bypass flows equivalent to those used clinically. Thus prolonged use of ECMO in unanesthetized lambs appears to be neither harmful nor beneficial to the steady-state dynamics of fluid exchange in the lung. Furthermore, total pulmonary blood flow is not a determinant of net fluid filtration across the lung microcirculation.

Animals↗