Biomedical subjects

A G Giumanini

Publications and source records attributed to A G Giumanini.

10 recordsLinked to original sources

PubMed2001

Improved method for the analysis of organic acids and new derivatization of alcohols in complex natural aqueous matrixes: application to wine and apple vinegar.

An improvement in the procedure for investigation of organic acids and a new derivatization method, amenable to gas chromatographic-mass spectrometric detection of alcohols, are presented. The latter is based on the formation of phenacetyl esters. The simultaneous application of the two methods also allows data to be obtained on some volatile neutrals present in complex natural aqueous fluids. Application to wine and cider vinegars allowed detection of a number of previously unreported components, among which are interesting partially esterified polycarboxylic esters.

Acetic Acid↗

PubMed2000

Gas chromatography-mass spectrometry-Fourier transform infrared spectrometry and high-performance liquid chromatographic characterization of mononitro- and dinitro-isomers from the nitration of N,N-dimethyldiphenylacetamide.

Gas chromatographic retention data, Fourier transform infrared and mass spectrometric (electron impact, electron attachment and methane chemical ionization) profiles are reported for the products of mono- and dinitration of N,N-dimethyldiphenylacetamide. Differentiations of analytical importance among isomers could be gathered by the study which led to their complete identification.

Acetamides↗

PubMed1980

Mass spectrometry of the metabolites of 2-ethyl-2,3-dihydro-5-benzofuranylacetic acid.

The electron impact induced fragmentations of the title compound, its methyl ester, its three hydroxy derivatives, namely, 3-hydroxy alpha- and beta-hydroxy, their acetyl methyl esters and its 2,3-dehydro derivative, have been studied in detail. Among the uncommon features of the observed processes were methyl acetate and C-2 and C-3 hydrocarbon expulsions and a few novel rearrangements. The ion at m/z 131 appeared as the terminal for many fragmentation sequences.

Acetates↗

PubMed1978

In vivo reaction of dimethylnitrosamine with nucleic acids.

7-Methylguanine is the main compound resulting from in vivo interaction between dimethylnitrosamine (DMNA) and nucleic acids, detected after strong acid hydrolysis. However, enzymic and alkaline hydrolysis of nucleic acids leads to quantitative liberation of methylamine. Methylamine isolated from liver nucleic acids of 15N-DMNA-treated rats has molecular weight of 31, thus demonstrating that DMNA-nitrogen is not involved in the binding.

Animals↗

PubMed1977