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Biomedical subjects

A G Marachev

Publications and source records attributed to A G Marachev.

At least 19 recordsLinked to original sources

[Myocardial catecholamine levels in patients with congenital and acquired heart defects].

Catecholamine levels were determined in the myocardial slices from 66 patients with congenital and acquired heart diseases by the trihydroxyindole++ method on a Lumilan fluorescence spectrophotometer. The patients were found to have greatly varying epinephrine and norepinephrine levels. The accumulation of catecholamine reflected, to a certain extent, the occurrence of disorders in relation to the functional load, hyperfunctions of the myocardium. Blood hypoxemia and myocardial hypoxia affected the status of the patients.

Epinephrine↗

[Use of normobaric oxygenation for preventive and therapeutic purposes].

Courses of normobaric oxygenation were performed in 72 healthy males (residents of the city of Arkhangelsk) and in 91 patients suffering from chronic nonspecific pulmonary diseases with respiratory insufficiency of I-II degree. Normobaric oxygenation led to the optimization of the CVS activity of northerners and an increase in their working capacity. The corrective role of oxygenation was more noticeable in persons with signs of dysadaptation. A favorable therapeutic effect of normobaric oxygenation in patients with respiratory insufficiency was not restricted to direct oxygen influence, its after-effects were lasting. Biochemical investigations indicated the absence of a toxic oxygen effect in this regimen of oxygenation.

Acclimatization↗

[Status of erythrocytes and erythropoiesis in alcoholics].

To identify changes in the status of red blood and erythropoiesis in alcoholism, the authors examined three groups of patients aged 18 to 60 years: (1) 146 patients with stage II alcoholism; (2) 97 patients with acute alcoholic hallucinosis; and (3) 76 patients with delirium tremens. The examination revealed a considerable tension of erythropoiesis and erythrodieresis, this being a compensatory response to prolonged and severe hypoxia. At the beginnings of the disease the amount of erythrocytes and total hemoglobin tended to increase, then with the development of psychoses it dramatically decreased resulting in anemia. With disease progression the mean volume of erythrocytes tended to increase consistently reaching the highest values in delirium. This may serve as one of the diagnostic markers of alcoholism to be used in combination with other laboratory tests and clinical findings. The identified decrease in the insulin depositing function of erythrocytes may also indicate that the pancreas has also been involved in the pathological process.

Adolescent↗

[Morphologic changes in erythrocytes during exposure of the body to cold].

Study of morphology of erythrocytes in residents of the Extreme North of the USSR and in experimental rats after prolonged effect of low temperatures established that the red blood system undergoes considerable rearrangement with the appearance of more marked polymorphism of erythrocytes. Adaptation reactions of the organism are accompanied by juvenation and increased destruction of erythrocytes simultaneously.

Acclimatization↗