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Biomedical subjects

A G Marchi

Publications and source records attributed to A G Marchi.

At least 19 recordsLinked to original sources
PubMed2006

[Short-stay observation in the Pediatric Emergency Room: a 2003-1993 comparison].

AIM: To evaluate the effectiveness of Short-Stay Observation (SSO) in the paediatric Emergency Room (ER) according to changes over time of guidelines. METHODS: This retrospective study analyses the probability of discharge immediately from ER or after SSO and of hospital admission in Trieste during 2003 as compared with 1993. Subjects aged under 18 with respiratory, urinary tract, neurological and gastrointestinal pathologies, selected symptoms and injuries were studied. RESULTS: In 2003 the 86.2% of 6 350 patients enrolled in the study were discharged immediately, compared with the 81.7% of 5475 subjects in 1993 (RR 1.05, IC 95% 1.04-1.07), the 10.0% were discharged after SSO, compared with the 5.9% in 1993 (RR 1.71, IC 95% 1.50-1.95). The 3.8% of the subjects were admitted in 2003, compared to the 12.4% in 1993 (RR 0.30, IC 95% 0.26-0.35). The role of SSO was particularly significant in case of pneumonia, URI, urinary tract infections, seizures, gastroenteritis, abdominal pain, infant fever, injuries. CONCLUSIONS: The decrease of hospital admissions, pointed out in 2003, are related to a better choice of candidates for SSO and to changes in guidelines concerning the approach to urinary tract infections and seizures, the treatment of respiratory distress and gastroenteritis dehydration, and the early identification of predictors of injuries complications. The study confirms the effectiveness of SSO in both avoiding inappropriate admissions and reducing those with limited needs of hospital assistance, assuring the quality of care. The reduced hospital stay decreases child and his family discomfort and favours the care continuity due to the involvement of family paediatrician.

Adolescent↗
PubMed2004

[Poisoning in first year of age. A multicentre study].

AIM: The aim of this study is to describe clinical and epidemiological features of toxic exposures in children under 1 year. METHODS: During 2001 a prospective study on poisoning was carried out in the Pediatric Emergency Departments (ED) of 14 hospitals. Information stored concerned epidemiological and clinical features, evaluation of accidental or deliberate manner of exposure as well as of clinical consequences. Data were compared with those registered in 1-4 year-old patients. RESULTS: During 2001 out of 1,026 children registered, 111 (10.8%) were under 1 year. Exposure occurred exclusively at home and by accident. As compared to 1-4 year-old patients, children exposures were more frequently due to parental errors (38.7% of cases vs 7.3%), and involved plant poisons (22.5% vs 7.3%). In 1/3 of these cases the cause was due to non-toxic exposures, in another 1/3 an early treatment avoided clinical consequences. In the other cases, symptoms were of low to moderate severity, only in 1 case they were serious. No deaths occurred. One out of every 3 children was admitted, the others were sent home directly from ED (23.4%) or after a short observation period (44.1%). CONCLUSION: The increase in poisoning in children under 1 year, as compared to previous multicentre studies, is deserving of concern. In spite of the relatively low severity they are completely preventable. The study shows that information on poisons prevention for parents needs to be improved to prevent exposure of children under 1 year to toxic substances at home.

Accidents, Home↗
PubMed1999

Permanent sequelae in sports injuries: a population based study.

AIM: To identify permanent sequelae after sports injuries in children and adolescents. METHODS: In 1985, a prospective register was drawn up of all sports related injuries reported that year by the residents of Trieste, Italy aged 6-15 years. Moderate to severe injuries (scoring >/= 2 on the abbreviated injury scale (AIS)) were the object of a longitudinal clinical study. In 1988, 30.9% of the 220 subjects enrolled had sequelae. A further follow up was undertaken in 1997. RESULTS: The follow up in 1997 involved 54 subjects (26 girls; average age 24.5 years). Subjective and objective sequelae, by now considered to be permanent, were found in 61.1%, corresponding to 15% of the AIS >/= 2 injuries recorded in 1985. The prevalence of sequelae was similar in the two sexes, in relation to the child's age at time of injury, and in the different sports practised. It was higher in relation to the severity of the lesion (89% of AIS 3 injuries examined, 56% of AIS 2 injuries) and to the type of lesion and its location. With regard to AIS >/= 2 injuries, permanent sequelae were found in 50% of ankle fractures, 43% of elbow fractures, 33% of leg/foot fractures, 25% of knee sprains, and 23% of ankle sprains. CONCLUSIONS: The frequency of sequelae in sports injuries in children and adolescents is high. The risk appears to be connected to certain anatomical and functional age characteristics. Prevention strategies should include specific assessment of physical fitness and adequate follow up after the accident, particularly rehabilitation.

Adolescent↗
PubMed1998

Childhood poisoning: a population study in Trieste, Italy, 1975-1994.

We describe the epidemiology of 1918 cases of childhood poisoning referred to the emergency room in Trieste, Italy, from 1975 to 1994. The incidence rate of emergency room referral and subsequent hospitalization was calculated on the basis of the distribution of children resident in Trieste by calendar year. The occurrence of childhood poisoning was described according to time trends, age and gender of the child, route of exposure, symptoms at presentation to the emergency room, role of the child or others, intention, and substance involved in the poisoning. The association between presence of symptoms and characteristics of referral, host factors and substances involved was evaluated by estimating the odds ratio in multivariate models. Possible determinants of the clinical decision to treat certain cases were evaluated using logistic regression. Despite an increasing incidence of referral (from 155 per 100,000 persons per year in 1975-79 to 352 per 100,000 in 1990-94), hospital admission rates showed a two-fold decrease. Younger children (age 0-4 years) were more likely to be asymptomatic and required treatment and hospitalization less often than older children (age > or = 10 years). Trends show a decrease in pharmaceutical poisonings due probably to the introduction of child-resistant containers and an increase in domestic poisons. We also observed a steady increase in carbon monoxide inhalation and alcohol poisonings, mostly among teenagers.

Adolescent↗
PubMed1997

[Alcohol consumption in schoolchildren. Results of a questionnaire study].

BACKGROUND AND METHODS: Alcohol is the leading cause of acute poisoning in Trieste teenagers and one of the main public health problems in general population. Planning of effective prevention is limited by lack of information on alcohol drinking habits and notions of young people. MATERIALS AND METHODS: A questionnaire study has been carried out on 769 school teen-agers in Trieste and Gorizia provinces. The anonymous questionnaire concerned alcohol use and daily consumption, age and site of first approach, favourite beverages, number of acute abuse during the last year, awareness of the problem and opinion on social aspects. RESULTS: Near half of school teen-agers reported alcohol drinking. First approach occurred more frequently at home, because of curiosity or parents emulation and it was especially precocious for wine and beer (mode 8-10 yrs) respect to spirits (mode 12 yrs). In males and in both gender with increasing age higher rates of drinkers, alcohol consumption and acute poisoning were reported. More than 8 of 10 children judged the alcohol to be not a food but a drug, whose consumption is not necessary to affirm the personality. However, for more that 8 of 10 subjects alcohol warms, for about half of them it is stimulant. Only 4 of 10 were aware that its sale is forbidden by law under 16 years of age. CONCLUSIONS: Due to early initiation, family responsibility and lack of awareness of the problem, a correct alcohologic information to families and teen-agers is needed. Pediatricians can and must have a main role at this regard, but their action must be associated with reduction of our society tolerance on alcohol drinking.

Adolescent↗
PubMed1995

Severity grading of childhood poisoning: the Multicentre Study of Poisoning in Children (MSPC) score.

Scores for severity grading of childhood poisoning may be useful in comparing different causes of poisoning, in order to identify the main risks and their changes over time. The Multicentre Study of Poisoning in Children score is based on four levels of severity (1-mild, 2-moderate, 3-severe, 4-very severe) involving nine target groups: seven relating to organ systems (gastrointestinal, nervous, respiratory, circulatory, renal, hepatic, skin), one to metabolic abnormalities and one to injuries from corrosive substances. Each patient is classified by the highest level attributed to any one of the nine groups. The score has been prospectively tested in 644 symptomatic children, aged 0-13 years, admitted to six pediatric hospitals of Northern Italy from January 1, 1991 to December 31, 1993. Poisoning was categorized as mild (1) in 357 children (53.8%), moderate (2) in 285 (42.9%), severe (3) in 18 (2.7%) and very severe (4) in 4 (0.6%). No deaths occurred. Severity grading according to The Multicentre Study of Poisoning in Children score confirms the prevalence of mild and moderate poisonings in children; the score seems to be an objective method suitable for epidemiological studies in different countries. Its clinical usefulness deserves more investigation.

Adolescent↗
PubMed1995

[Evaluation of temporary observation and short hospital stay in a pediatric emergency department].

Temporary observation is a very short stay in Emergency Department, widely carried out in adult patients in our Country. No experience in childhood has been reported. In our emergency department children under 16 with acute diseases are admitted for 24-48 hours. From 1991 we carried out also temporary observation. Its effectiveness has been evaluated by studying our activity in 1992 (14.574 emergency room visits, with 664 admissions to our Department and 274 temporary observation) and 1993 (12820 emergency room visits, 573 admissions, 428 temporary observation). Compared to 1992, in 1993 there was a decrease of both emergency room visits (higher than expected from demographic lowering and in part due to payment for emergency room visits) and hospital admissions, and an increase of temporary observation. The stay in hospital was less than 6 hours in 94.2% of temporary observation patients. 18.2% of them were evaluated on clinical basis, 57% also by diagnostic examinations, 24.8% had some treatment. The 89% of the children were sent home following temporary observation, the others were admitted. Criteria for temporary observation were fairly similar to those for hospital admission, but not far as Central Nervous System and Renal Disease are concerned. Our study confirms the usefulness of temporary observation in childhood to reduce both the number of hospital admissions and the discomfort of the patient and his family. Nevertheless there is a need of criteria of appropriateness. Therefore we have elaborated guide lines for temporary observation and admission to our Department.

Child↗
PubMed1994

The risk associated with poisonings in children.

The risk associated with poisonings in children was assessed on 6175 subjects admitted to the pediatric hospitals of 3 regions of Northern Italy between 1975 and 1990. The frequency of exposures and the severity of sequelae allowed high- and low-risk substances to be identified. Risks were studied separately in the 0-4, 5-9 and 10-13 y age group to determine age-related differences. A decrease in drug-related poisonings and an increase of those caused by household products, particularly in the first 2 y of life, were observed in 1983-90 as against 1975-82 in association with the introduction of safety caps and containers for drugs. Our study points out the need to strengthen active primary prevention through health education and parental and adolescent information, and to improve passive prevention through the extension of safety closures to household products.

Adolescent↗
PubMed1993

[Approach to acute gastroenteritis in children: comparison over the years].

Diagnostic and therapeutic approach to children admitted because of acute gastroenteritis has been retrospectively evaluated by auditing the hospital records in two periods respectively before (A: 103 patients) and after (B: 133 patients) the use of oral rehydration solution. Incomplete history taking was found out without differences between the two periods; in many cases the weight loss, one of the main criteria for hospitalization in acute diarrhoea, was not recorded at admission. In period B therapeutic behaviour was adequate to literature guidelines as regards both antibiotic prescription and use of oral rehydration solution. Nevertheless even if oral rehydration was carried out in more than 70% of patients, parenteral fluid administration was not significantly reduced in comparison with period A. Oral rehydration solution contributed to reduce the length of hospital stay in the more recent period. The study confirms the usefulness of medical audit to improve quality care.

Acute Disease↗
PubMed1993

[Child abuse by intoxication].

Child abuse by toxic substances is not easy to identify due to both the lack of signs of physical violence and the high incidence of accidental poisonings. Twelve cases of documented abuse, out of 6175 poisonings in children aged 0-13 years, were registered during 1975-1990 at Genova, Torino and Trieste Children Hospitals. In other 139 children the suspicion of abuse couldn't be confirmed. An early suspicion of abuse, is needed to prevent abuse and help the child and his family.

Adolescent↗
PubMed1992

[Evaluation of a pediatric emergency room: ten years later].

Utilization of the pediatric Emergency Room has been evaluated during the year 1991, by a questionnaire study on 694 children. By comparison with a previous research in 1981 it was possible to identify a further decrease of urgent and appropriate visits with increase of those inappropriate. Visits were more frequently urgent of appropriate in case of acute health problems, inappropriate if related to recurrent problems. Without considering true emergencies, three main causes for ER consultation have been identified: family custom, inappropriate relationships with the practitioner, dependence on the hospital. In the first group of children most of the visits proved inappropriate. The study points out a further increase of inappropriate utilization of ER, due mainly to inappropriate relationships between the family and the practitioner. This has to be corrected to reduce costs and improve child care.

Adult↗
PubMed1992

Epidemiology of children poisoning: comparison between telephone inquiries and emergency room visits.

We studied 674 telephone inquiries to the Poison Information Centre and 532 Emergency Room (ER) visits due to suspected poisonings in 1018 children below the age of 16 y and living at Trieste. The cases were prospectively recorded during 1985-1989. Age distribution, toxic substances and consequences were different in the 2 groups. Telephone inquiries concerned children below the age of 5 y more frequently, and most of the exposures were assessed as non-toxic. Among children admitted to the hospital ER, 22.2% were more than 10-y old, and of these 79.7% were confirmed poisonings. This study demonstrated the need to take account of both Poison Control Centre and ER data to get reliable information on the occurrence of poisonings in children.

Adolescent↗
PubMed1991

Evaluation of changing patterns in children poisonings and prevention.

Poisoning prevention strategies have to be modified according to the risk variations with age and time. Epidemiologic surveillance usefulness was confirmed by studying the 0-15 y-old children in the Trieste area from 1976-1987. Significant differences were observed in children under 5 due to an increase in caustic substance and home detergents poisoning and a decrease in analgesic-antipyretics ingestion. This was probably due to the introduction by law in our country of child-resistant containers and to a better awareness by parents. At 10 y-of-age and older, alcohol is the cause of most intoxications and more recently benzodiazepine poisonings have significantly increased. At this age poisoning results from deliberate ingestion in most cases; therefore education should be the main preventive strategy.

Adolescent↗
PubMed1990

[Traffic-related injuries in children at Trieste, 1984-1986].

Traffic-related injuries to children are poorly known in our country, in spite of their role in mortality and morbidity. Being that they are rather different from those reported in the adults, their study is useful in identifying risks and elaborating prevention strategies. This paper reports epidemiologic and clinical data on 1050 children under 16, referred to our hospital because of road traffic accidents. The study has been prospectively carried out during 1984-86; injuries severity was assessed according to the Abbreviated Injury Scale. Incidence rates resulted to increase with the age, highest values being observed for 15 year old children, due to motorcycle use. Patterns and severity of the injuries were significantly different according to the age and the group of injured subjects. Younger children as pedestrians and 14-15 y.o. motorcyclists resulted to be more involved than car passengers and bicyclists. At a telephone inquiry after 6-12 months sequelae resulted in 20-40% out of 482 children, according to different AIS Score.

Accidents, Traffic↗
PubMed1990

[The sports, the child and accidents. III. Long-term sequelae].

Sports-related injuries in children and adolescents are an emergent health problem in our country, because of their incidence and severity. Nevertheless information is lacking on possible long term sequelae. This topic has been studied in 220 out of 1040 6-15 years old children, prospectively registered during 1985 in our hospital because of acute sports injuries. Selection for the follow-up was based on injuries severity, assessed according to the Abbreviated Injury Scale. Subjective and/or objective sequelae have been observed at a clinical control three years after the accident, in 68 out of the 220 controlled children (30.9%). The prevalence of the sequelae was similar in males and females, but quite different according to the age, being higher in children older than 14, the type of sports activity and the site of the injuries, with higher prevalence of those of the ankle and knee rather than of the wrist. Prevention of sports-related injuries and their possible sequelae is well established in Sports Medicine, but not yet fully applied to children. Pediatricians must sensitize the school and sports clubs to the problem.

Adolescent↗
PubMed1989

[Evaluation of the usefulness of the motorcycle helmet in adolescents in Trieste].

The effectiveness of the motorcycle helmet was assessed in 359 accidents involving adolescents under 16 in the Trieste area in 1985-88. Comparison of the 18 months preceding and following the introduction of the law revealed that helmet use significantly reduced the number and gravity (as objectively assessed using the Abbreviated Injury Scale) of cranial and facial injuries but made no significant difference to other areas. The 70-80% reduction in head injuries also significantly reduced the incidence of multiple injuries and hospital admissions. The effectiveness of the helmet demonstrated in this study primarily concerned with motorcycle accidents in urban areas suggests that it should now also be made obligatory for those currently exempt.

Accidents, Traffic↗
PubMed1989

Epidemiology of urinary tract infections and vesico-ureteral reflux in children.

The purpose of this study was to assess the incidence of symptomatic urinary tract infection (U.T.I.) and malformations, such as vesico-ureteral reflux (V.U.R.), in the Trieste area. Data were collected in the framework of a survey based on the application of a protocol on urinary infections between 1979 and 1983. The U.T.I. incidence was found to be 1.38% of the 0-14-year-old residents, with a higher frequency in females (2.36%) than in males (0.46%). As regards V.U.R., the incidence in the population studied turned out to be 0.25%, with a females/males ratio of 4:1. Striking differences in incidence data were observed according to the age of U.T.I. and V.U.R. diagnosis and to the infection level (cystitis or pyelonephritis). The incidence of renal scarring resulted to be extremely low, which can be ascribed to the early diagnosis in our cases.

Adolescent↗