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Biomedical subjects

A G Morrison

Publications and source records attributed to A G Morrison.

7 recordsLinked to original sources

Malignant hyperthermia during prolonged surgery for tumour resection.

The onset of malignant hyperthermia in a patient during a prolonged anaesthetic for tumour resection is described. The onset was delayed with a gradual rise in heart rate and PETCO2 before becoming fulminant; muscle rigidity was not a feature. Other aspects of the patient's condition confused the presentation, delayed the diagnosis and may have been involved in precipitating the event. However, it responded rapidly to treatment and surgery was continued. A possible recrudescence occurred 18 h later. Malignant hyperthermia should be considered early in cases of unexplained tachycardia or rising PETCO2.

Adult

Malignant transformation of eccrine spiradenoma.

Two patients are described in whom malignant transformation occurred within an eccrine spiradenoma. Their findings were compared with those of six similar patients from the literature, and a characteristic clinicopathologic picture was evident. The typical history was one of rapid enlargement of a cutaneous nodule of long standing. The neoplasms were composed, at least in part, of large, markedly atypical basaloid cells with numerous mitotic figures. Adjacent benign spiradenoma was observed microscopically in each case, and some of the carcinomas retained architectural features reminiscent of spiradenoma. One patient died of disseminated tumor, but follow-up was short or lacking in several cases. Malignant transformation of eccrine spiradenoma shares many clinical and pathologic features with malignant transformation of dermal cylindroma.

Adenoma, Sweat Gland

Pseudo-iniencephaly. A case report.

A case of congenital webbing with other congenital abnormalities is presented. Initial examination of the features of the case made a diagnosis of iniencephaly seem likely. However, further examination of the radiographs and the physical abnormalities demonstrated too few of the typical features, and the term pseudo-iniencephaly has been used to describe the case. The various aetiological possibilities are discussed, but it is clear that further research into webbing and its concomitant abnormalities would be necessary to provide the answers to the questions posed by this case.

Abnormalities, Multiple