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Biomedical subjects

A G Turner

Publications and source records attributed to A G Turner.

17 recordsLinked to original sources
PubMed1991

Are patients' attitudes the cause of long waiting lists?

This paper studies the rate of non-attendance for both out-patient clinics and in-patient care. It relates this to the waiting times for both services. If all patients who did not attend clinics had informed us beforehand, thus enabling us to give their appointments to other patients, the out-patient waiting time could have been reduced from six months to one week. If a similar approach was taken with the in-patient waiting list, the waiting time could have been reduced from 15 months to nine months.

Appointments and Schedules↗
PubMed1979

A trial of bleomycin versus adriamycin in advanced carcinoma of the bladder.

Thirty-seven patients were studied in a controlled clinical trial to assess the value of Adriamycin and Bleomycin in the treatment of advanced carcinoma of the bladder. The previously reported high response rates for both drugs were not observed in this trial. Administration of Bleomycin was accompanied by a toxicity rate so high that treatment had to be abandoned. Neither Adriamycin nor Bleomycin, therefore, used as single agents, have a role in the chemotherapy of advanced bladder cancer. Other agents should be investigated and assessed by controlled clinical trials that are disease-orientated rather than drug-orientated.

Bleomycin↗
PubMed1977

A haematuria diagnostic service.

In a haematuria diagnostic service, covering experience with 95 patients, 12 new cases of cancer of the bladder, one of cancer of the kidney, and one of cancer of the penis were identified--all at an early stage. Patients presenting with haematuria were investigated rapidly without disruption of the routine work of the urological unit. Patients who identified the symptoms and sought advice early were given a definite diagnosis quickly, and treatment for any malignant disease was started early. The delay that undoubtedly endangers patients' lives has been considerably reduced by this service.

Adolescent↗
PubMed1977

The clinical diagnostic value of the carcinoembryonic antigen (CEA) in haematuria.

Plasma and urinary CEA levels in patients presenting with haematuria have been studied to assess whether they facilitate the differentiation between benign and malignant urothelial conditions. Plasma CEA is of no diagnostic value although, if raised, it may suggest an invasive tumour. Urinary CEA levels are only of value in the absence of urinary infection; even then, only 37% of the cases with overt urothelial tumours had raised titres. A knowledge of the urinary CEA level, therefore, would seem to contribute little to the diagnosis of patients presenting with haematuria and all patients must still be investigated by the conventional techniques of urinary bacteriology, cytology, intravenous pyelography and cystourethroscopy.

Carcinoembryonic Antigen↗
PubMed1977

The treatment of advanced bladder cancer with methotrexate.

61 patients with advanced bladder cancer were treated with methotrexate. 3 different regimes were used, 2 given on an out-patient and 1 on an in-patient basis. A response rate of 56% was found in patients who received 100 mg of methotrexate intravenously every 2 weeks as an out-patient. Provided that renal function is checked before therapy and is normal, then methotrexate can be used safely; it being well tolerated and having few serious side-effects.

Bone Neoplasms↗
PubMed1976

The value of lymphography in the management of bladder cancer.

228 bilateral pedal lymphograms in patients with bladder cancer have been correlated with the features of the primary bladder tumour and patient survival. In 70 cases, radiographic findings were correlated with operative node histology. The results show that it is not possible to predict accurately which cases have lymphatic spread without this investigation. Positive lymphograms were found in 91 cases, and were associated with a very poor prognosis. Only 6% of patients with unilaterally involved iliac nodes survived 5 years, and all patients with bilateral iliac or para-aortic disease died within 3 years. Histological correlation was found in 90% of cases, and the results indicate that this investigation slightly underestimates the incidence and extent of microscopic lymphatic metastases. It is concluded that this investigation is essential in planning the treatment of infiltrating bladder tumours.

Follow-Up Studies↗
PubMed1975

Calibration of the Anderson 2000 disposable air sampler.

The Anderson Disposable Sampler is an efficient instrument for collecting airborne particles in the size range 0.8 to 10.5 microns. When used for microbiological aerosols, we would expect almost 100% of the particles in this size range to be collected. These particle sizes are of special significance for anyone interested in respiratory and other infections in hospitalized patients. The 50% effective cut-off diameter of stage 1 of this sampler is 8.0 microns for spherical particles. This instrument is simple to operate, uses standard size Petri dishes, has a high collection efficiency, and does not require a flow regulator. It should find wide use in hospitals, clean room technology, and industrial applications where microbial air quality is significant.

Aerosols↗
PubMed1975

Bacterial aerosolization from an ultrasonic cleaner.

An ultrasonic device used for cleaning surgical instruments was found to produce a significant microbial aerosol. No correlation was found between the concentration of aerosol generated and the bacterial contamination in the cleaning solution. Table top contamination around the cleaner was due essentially to splash and dripping, and not from the settling of the aerosol. Recommendations are made for cleaning and disinfection protocols.

Aerosols↗