[Somato-autonomic coupling in the central command to move].
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Biomedical subjects
A G Vylegzhanin
Publications and source records attributed to A G Vylegzhanin.
[Effect of clonidine and naloxone in somatovegetative responses in decerebrate cats].
Experiments on decerebrated curarized cats were performed to study changes in the basal level of arterial pressure, cardiac output and blood flow in the common iliac artery, as well as hemodynamic reactions induced by the central command to the skeletal muscles during fictitious scratching after administration of clonidine in a dose of 30 microgram/kg and naloxone in a dose of 0.12-0.15 microgram/kg. Clonidine decreased the blood flow in the iliac artery, exerting a negligible effect on other hemodynamic parameters. The pressor reaction of arterial pressure during the central command to the skeletal muscles decreased by 8 mm Hg under the effect of clonidine, while the appearance of the activity periods in the gastrocnemius nerve was facilitated and increased. Naloxone administered in the presence of clonidine elevated arterial pressure by 14 mm Hg, having no effect on evoked responses on the part of the cardiovascular system.
Animals↗
[Structure of hemodynamic responses in the central command to move].
Cardiac and vascular components of the hemodynamic response to "central command" to the skeletal muscles in immobilized decerebrated cats using an experimental model of "fictitious scratching" revealed that activation of the m. gastrocnemius increased blood pressure by 57 mm Hg, whereas cardiac output and blood flow in the common iliac artery changed insignificantly. The maximal increase of the blood flow in common iliac artery depended mainly on the stimulation of beta-adrenoreceptors by circulating catecholamines. The adaptive cardio-vascular responses during "central command" to skeletal muscles seem to depend mainly on the elevation of peripheral vascular resistance, there being no specific vasodilator influences on blood vessels of the muscles receiving the "central command".
Animals↗