Interferons and interstitial lung disease.
Explore the source record for details and available documents.
Biomedical subjects
Publications and source records attributed to A G Wilcox.
Explore the source record for details and available documents.
High resolution computed tomography (HRCT) has considerably improved the ability to diagnose and characterize interstitial lung disease (ILD). This paper assesses the role of HRCT in evaluating small airway disease associated with ILD particularly sarcoidosis, hypersensitivity pneumonitis, and interstitial pulmonary fibrosis.
Recently, with radiology some advances have been made in the care of patients with interstitial lung disease, predominately through the use of high-resolution computed tomography. This technique is helpful not only in the diagnosis of interstitial lung disease, but also in patient follow-up and management. Other techniques, including nuclear medicine and magnetic resonance imaging, have limited but well-defined uses. Positron emission tomography is a promising nuclear medicine technique, but its benefits have not been substantiated in the literature.
The purpose of this study was to illustrate high-resolution computed tomography (HRCT) findings in symptomatic adult Gaucher's disease patients. Five adult patients with Gaucher's disease experienced dyspnea. These patient were first evaluated by chest X-ray (CXR) followed by HRCT. The chest X-ray on one patient demonstrated a calcified granuloma. Two patients had interstitial disease only seen on HRCT, and two patients had a combination of interstitial and alveolar disease giving a mosaic pattern better illustrated on HRCT. HRCT can be used following CXR to evaluate lung pathology in symptomatic adult Gaucher's disease patients.