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Biomedical subjects

A G Zabozlaev

Publications and source records attributed to A G Zabozlaev.

11 recordsLinked to original sources

[The antiatherosclerotic effects of a polysaccharide from raw animal stock].

The data obtained showed that the polysaccharide diminished the blood levels of cholesterol, beta-lipoproteins, and triglycerides, the concentrations of cholesterol in the liver and thoracic aorta in experimental atherosclerosis. It is concluded that the polysaccharide is promising in designing a new anti-atherosclerotic drug.

Animals↗

[Solcoseryl: Ulcerostatic effect and possible mechanisms].

It is shown that the level of DNA, RNA, collagen, non-collagen proteins, hexoses and glycosaminoglycans is changed when making the experimental gastric ulcer in rats. Solcoseryl stabilises the level of DNA, RNA and collagen, stimulating the reparation processes in ulcer.

Actihaemyl↗

[Isopropoxyhermatran--a stimulant of hepatocyte regeneration].

It was shown that isoproxihermatran (IPH) (40 mg/kg) administered intraperitoneally in rats with lobectomy of heparin stimulates development of hepatocytes' dimensions and decrease of oxygen transmission velocity through the mitochondrial membranes in this cells. Antioxidant properties of IPH have been detected. Stimulating activity of IPH at heparin secretion of bile.

Animals↗

[Ulcerostatic effect of tris-[2-hydroxyethyl] ammonium salt of iron-containing polyacryl acid and its possible mechanisms].

The study investigated a stimulating effect of tris-[2-hydroxyethyl] ammonium salt of iron-containing polyacryl acid on proliferative processes in the connective tissue in development of experimental gastric ulcer. The drug was found to exhibit an ulcerostatic effect, to change the levels of collagen, noncollagen proteins, glycosaminoglycan fractions, DNA and RNA.

2,3-Diketogulonic Acid↗

[Krezatsin--a stimulant of the activity of regenerating liver cells].

In experiments with partial hepatectomy in rats, the application of cresacin was shown to potentiate processes of hepatocyte regeneration, to increase high-energy compounds therein, and to accelerate some phases of mitotic cycle. These processes occur along with an inhibition of lipid peroxidation in hepatocytes, a decrease in the rate of transmembrane oxygen transport in mitochondria, and a reduction of cytochrome oxidase amount. It was concluded that cresacin directly stimulates diverse links of metabolic pathway.

Acetates↗