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Biomedical subjects

A G el-Missiry

Publications and source records attributed to A G el-Missiry.

9 recordsLinked to original sources

Serum levels of tumour necrosis factor- alpha in schistosomiasis mansoni and their analogous changes in collagen diseases and schistosomal arthropathy.

Serum levels of TNF-alpha was quantitatively estimated by the use of solid enzyme amplified sensitivity immunoassay (EASIA) in different stages of schistosomiasis mansoni, rheumatoid arthritis (RA), systemic lupus erythematosus (SLE) and schistosomal arthropathy. Statistically, significant higher levels were detected in the different groups compared to the normal control group. The level was found highest in hepatosplenic schistosomiasis with ascites (group 1c). The difference was significantly higher compared to cases of early S. mansoni infection (group Ia) and insignificant compared to hepatosplenic schistosomiasis without ascites (group 1b). No significant difference was detected comparing groups 1a and 1b, or groups 2a (RA) and 2b (SLE). Cases of schistosomal arthropathy (group 3) showed significantly higher level compared to groups 1a and 1b, although the level in group 1c was still significantly higher compared to group 3, the level was also significantly higher in group 3 compared to cases of RA but not to cases of SLE.

Arthritis, Infectious↗

Specific immunoglobulins in schistosomiasis.

Specific and total immunoglobulins antibodies levels to Schistosoma antigens were determined in 44 patients with S. mansoni infection. No Significant increase was observed in parasitic specific IgG, IgM, and IgA levels in both acute and chronic infections. On the other hand, Significant increased specific IgE antibodies was demonstrated in both acute and chronic infections of bilharziasis. The results revealed that increased immunoglobulins was not Specific to Schistosomiasis infection. Also, No correlation was observed between clinical course of the infection and immunoglobulins levels.

Animals↗

Distribution of Phlebotomus species in the Nile Delta, Egypt.

The importance of sandflies of the genus Phlebotomus being in the fact that some species are the vectors of leishmaniasis and other pathogenic organisms such as virus of sandfly fever. In Egypt, cutaneous leishmaniasis and sandfly fever are known and recently visceral leishmaniasis has been identified in Alexandria. Consequently, there is a need to study the geographical distribution of Phlebotomus species and to present an illustrative key for their identification. In the present study, four species of Phlebotomus were reported; P. papatasi, P. sergenti, P. langeroni and P. bergeroti. While P. papatasi is a known vector of zoonotic cutaneous leishmaniasis, P. langeroni is an incriminated vector for infantile visceral leishmaniasis, P. papatasi is the predominant species in the Nile Delta, but P. langeroni is found in West Alexandria and as a very rare species at the Libyan Egyptian borders. The whole results were discussed.

Animals↗