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Biomedical subjects

A Gómez García

Publications and source records attributed to A Gómez García.

8 recordsLinked to original sources

[Use of oral lipid-lowering drugs in patients with type-2 diabetes mellitus].

OBJECTIVE: To investigate whether oral lipid-lowering drugs (OLL) are used in line with the Mexican Official Regulation (NOM)-015-SSA-1994 for preventing, treating, and monitoring diabetes mellitus 2 (DM2) patients. DESIGN: Observational, descriptive study. SETTING: Primary care. Unit of Family Medicine (UMF) No. 80 of the Mexican Social Security Institute. PARTICIPANTS: 332 patients diagnosed with DM2, taking pharmacological treatment and with recent laboratory studies. MAIN MEASUREMENTS: Age, body mass index (BMI), years of evolution of diabetes, type of medication and OLL dose, time taking OLL, glucose, total cholesterol, and triglycerides. The patients were divided into 2 groups on the basis of the BMI: group 1 with BMI<27; group 2 >=27. In addition, each group was sub-divided by the type of medication. RESULTS: Glibenclamide was the OLL most prescribed (52% in both groups). In group 1 there were significant intra-group differences between patient's age and years of evolution of diabetes, whereas in group 2 only the metformin sub-group was associated with lower glucose concentrations and higher concentrations of triglycerides than in the other sub-groups. All patients had deficient glucaemia control. CONCLUSIONS: The data show that OLL treatment for DM2 patients varied from the NOM. Unification of criteria in primary care for the prescription pattern and the use of OLL for better metabolic control of this kind of patient were recommended.

Administration, Oral↗

[Glycosylated hemoglobin (HbA1) in pregnancy].

The life style, genetic predisposition and metabolic changes occurring during pregnancy can modify the percent value of glycated hemoglobins (HbA1 and HbA1c). In addition, research papers from different laboratories in the world have reported contradictory results on this respect. The purpose of this trial was to know the percent value of HbA1 in healthy women, during the different trimesters of pregnancy. 206 pregnant (E) healthy women who came over for prenatal control to UMF No 80 IMSS in Morelia, Michoacan with no previous history of Diabetes mellitus or Essential Hypertension were classified by trimesters of pregnancy (1T, 2T, 3T) and chronological age (I, 18-24; 11, 25-30; III, 31-35 years). Their chronological and gestational ages, weight, height, body mass index and parity were recorded. % HbA1 (ion exchange chromatography) was determined on each patient. Control group was formed by 187 non pregnant healthy women (NE) chosen with same criterion that pregnant women. % HbA1 was lower in E during pregnancy (7.11 +/- 1.53 vs 7.78 +/- 1.12%, p < 0.0001) than NE group. % HbA1 in E group was lower in the 1T and 2T than in the 3T (p < 0.001), same situation was observed in 18 to 24 (group I) and 25 to 30 (group II) years old. In the other hand, in E from group II on the 2T the weeks of gestation were correlated with % HbA1 (r = 0.72, p < 0.05). This results show a diminished HbA1 percent in E group with a lower values in the 1T and 2T. Moreover, these results will allow us to know HbA1 appearance in diabetic pregnant women and to evaluate the degree of metabolic control.

Adult↗

[Brachial plexus palsy associated with birth. A review of 30 cases].

OBJECTIVE: Our objective was to perform an updated analysis of the incidence and risk factors during pregnancy and labor related to obstetrical brachial palsy. PATIENTS AND METHODS: A retrospective study of all cases of brachial palsy associated with birth detected in our hospital between January 1994 and March 1998 was performed. Data recorded included age of mother, parity, gestational age at the moment of birth, type of birth, presentation, duration of delivery, sex of child, weight, Apgar test at 5 minutes, arterial pH of umbilical cord, type of brachial palsy, side affected and association with other injuries. RESULTS: Thirty cases of brachial palsy associated with birth were diagnosed. The incidence was 1.04%. In addition to a high birth weight, other factors related to the increase in the incidence of obstetric brachial palsy were the presence of dystocia of shoulders at birth, the use of forceps and Apgar and pH under the usual limits. No case of distal paralysis was found. CONCLUSIONS: This study demonstrates the influence of the risk factors known in the development of brachial palsy associated with birth. However, it also establishes doubts about the etiology of traction as the only cause. In addition, it stresses the necessity of adequate birth planning of babies suspected of being macrosomic.

Brachial Plexus↗

[Wolman's disease].

We present two brothers with Wolman's disease under its child form. Adrenal calcification, a diagnostic suspicion sign, was present in the second brother only. Vacuolated cells in bone marrow and intestine villi shown in pathological study, and cholesterol crystals in Kupffer cells were determinative. Acid esterase (0.85 nmol/mg/m) in fibroblast culture in the second brother was pathognomonic (normal values: 30 nmol/mg/m). Enzymatic values in parents were normal. Evolution in both cases was to early death, five and eight months respectively. Enzymatic study in amniotic cells culture over fifteen week of a third bearing was normal.

Acetylesterase↗

[Goldenhar syndrome. Discordance in monozygotic twins].

Child here described is a new-born male, the firstborn twin, who showed clinical-radiological manifestations compatible with an oculo-auriculo-vertebral syndrome or Goldenhar's syndrome. A comparison of chromosomes, identification of serological types and determination of antigens of histocompatibility (HLA) showed them to be similar in both twins, thus showing identity of monozygots . Of great importance in the anamnesis is a radiological study--cholecystography--which was practiced between 4th and 6th weeks of pregnancy. Differences shown and possible intervention of radiation as etiology mark the especial interest of this case.

Abnormalities, Radiation-Induced↗

[Arterial pressure in the school-age child; distribution and correlation with chronological and anthropometric variables].

The aim of the present study is to establish the normal patterns of blood pressure and the correlations with chronologic and anthropometric variables (age, body, weight, body height and body surface) in childhood. Blood pressures were taken in 1,310 children (727 male, 583 female) ages 4-14 years employing mercury sphygmomanometer, and taking for assessment of diastolic pressure Korotkoff's fifth phase. Study of single correlations showed significant increase of systolic blood pressure with every variable (p less than 0.001); the more predictable was body weight, and the less one, age. There were not significant relationships between diastolic pressure and any other variable; in the same way, there were not significant differences of blood pressures between both sexes. Multiple correlations established the following predictive order: Body weight, age and height. Authors show empirical and theoretical percentiles of blood pressure in relationship with variables: Age, body height and body weight.

Age Factors↗