Biomedical subjects

A Gahleitner

Publications and source records attributed to A Gahleitner.

At least 19 recordsLinked to original sources

PubMed2002

Optimization of the composition of phantom materials for computed tomography.

Using available data for photon attenuation and tissue composition, a computer code was developed for the optimization of the composition of phantom materials for diagnostic radiology. The code allows selection of attenuation data in a photon energy range from 1 to 150 keV and the choice of a suitable weight function in the energy interval chosen. For applications in CT imaging a weight function is available reflecting the contribution of the x-ray spectrum to the CT-signal. Several phantom materials for CT were optimized (body fat, trabecular bone, an average bone composition for C4 vertebrae and water) by varying the mineral components in a polymer base in order to adjust x-ray attenuation properties. Measurements with the water equivalent material (PSPP1) showed good agreement of calculated and measured HU values (AHU = 7.3 +/- 5.3 at 80 kVp and 4.0 +/- 2.7 at 140 kVp) and little variation of HU for tube voltages from 80 to 140 kVp. The method provides a fast and flexible means for obtaining optimized phantom materials for a large variety of tissue compositions and energy ranges.

Adipose Tissue↗

PubMed2002

Temperature dependence of HU values for various water equivalent phantom materials.

The temperature dependence of water equivalent phantom materials used in radiotherapy and diagnostic imaging has been investigated. Samples of phantom materials based on epoxy resin, polyethylene, a polystyrene-polypropylene mixture and commercially available phantom materials (Solid Water, Gammex RMI and Plastic Water, Nuclear Associates) were scanned at temperatures from 15 to 40 degrees C and HU values determined. At a reference temperature of 20 degrees C materials optimized for CT applications give HU values close to zero while the commercial materials show an offset of 119.77 HU (Plastic Water) and 27.69 HU (Solid Water). Temperature dependence was lowest for epoxy-based materials (EPX-W: -0.23 HU degrees C(-1); Solid Water: -0.25 HU degrees C(-1)) and highest for a polyethylene-based material (X0: -0.72 HU degrees C(-1)). A material based on a mixture of polystyrene and polypropylene (PSPPI: -0.27 HU degrees C(-1)) is comparable to epoxy-based materials and water (-0.29 HU degrees C(-1)).

Biomimetic Materials↗

PubMed2002

Pathophysiology and imaging in inflammatory and blastomatous synovial diseases.

Variable pathologies are subsumed under the term "synovial disease", including common pathologies such as rheumatoid arthritis. While formerly radiologists had to rely on conventional radiographs and bone scintigraphy with their inherent problems in visualizing soft tissue, noninvasive imaging of the synovium has recently improved substantially with the technical development of MRI and (Doppler) ultrasound. These imaging modalities allow differentiation of characteristic pathologic features based on a profound knowledge of normal anatomy and pathophysiology.

Arthritis, Infectious↗

PubMed2002

MRI of the cartilage.

With the introduction of fat-suppressed gradient-echo and fast spin-echo (FSE) sequences in clinical routine MR visualization of the hyaline articular cartilage is routinely possible in the larger joints. While 3D gradient-echo with fat suppression allows exact depiction of the thickness and surface of cartilage, FSE outlines the normal and abnormal internal structures of the hyaline cartilage; therefore, both sequences seem to be necessary in a standard MRI protocol for cartilage visualization. In diagnostically ambiguous cases, in which important therapeutic decisions are required, direct MR arthrography is the established imaging standard as an add-on procedure. Despite the social impact and prevalence, until recent years there was a paucity of knowledge about the pathogenesis of cartilage damage. With the introduction of high-resolution MRI with powerful surface coils and fat-suppression techniques, visualization of the articular cartilage is now routinely possible in many joints. After a short summary of the anatomy and physiology of the hyaline cartilage, the different MR imaging methods are discussed and recommended standards are suggested.

Cartilage, Articular↗

PubMed2002

[Coxarthrosis].

Osteoarthritis of the hip joint is a very common disease. There is a minor prevalence of males. By etiology one can distinguish primary (idiopathic) from secondary osteoarthritis. Secondary are due to well-known etiologies as overweight, repetitive traumata, malposture, muscle- and tendon-imbalance etc. Osteoarthritis includes not only cartilage abnormalities, but also such of the subchondral-region, synovialis, synovial fluid and periarticular muscles. The cartilage shows in osteoarthritis typically edema and swelling, defects with tears, fibrillation, and "baldness" and (or) cartilagenous repair-islands and joint space narrowing as well, while subchondrally micro-edema, necrosis, ev. microfractures, "cysts", demineralisation followed by sclerosis, osteophyte-formation and deformity is seen. With conventional radiographs and CT joint space narrowing, subchondral cysts, sclerosis and osteophytes and deformities are well delineated, MRI however allows visualization of subtle bone marrow and cartilage abnormalities. Clinically, the diagnosis of pre-osteoarthritis becomes more and more important. This includes e.g. deformities and malpostures, labrum-pathologies and structural imbalances. There are three prognostic different types of hip-osteoarthritis depending on the migration of the head of the hip joint: the most common are the latero-cranial and the medio-caudal ones, while the central one is found very rarely. Basic imaging method are conventional radiographs, and CT, followed by MRI. The diagnosis of an "activated osteoarthritis" is made by bone-scintigraphy or MRI with i.v. application of contrast-media. The labrum- and cartilage diagnosis should be done with MRI or MR-arthrography. Functional computer-animated analysis will be of great diagnostic value in the near future. MRI indications are differences between clinical results and imaging, missing clinical improvement of an "activated" osteoarthritis under standard therapy, unclear joint-pain and before any arthroscopy.

Aged↗

PubMed2002

Dental CT evaluation of mandibular first premolar root configurations and canal variations.

OBJECTIVES: Routine dental CT scans were used to describe mandibular first premolar root configurations and canal variations. STUDY DESIGN: One hundred twenty dental CT examinations were evaluated for mandibular first premolar root configurations and canal variations regarding shape of root and root canal, incidence of multiple canals, and level of bifurcation. RESULTS: A total of 17 teeth in 12 patients showed mesial invagination of the root of the mandibular first premolar. One root displayed 3 canals with 3 apical foramina. In 2 teeth, a single canal divided into 2 canals, but merged into 1 apical foramen. One root showing 2 root canals finally divided into 2 roots near the apex. Thirteen roots had 2 canals and 2 apical foramina. The distance from the cementoenamel junction to the level of bifurcation was between 4 and 13 mm (mean, 7.4 mm). CONCLUSION: The occurrence of incidentally found mandibular first premolar root variations should be an important component of dental CT reports.

Bicuspid↗

PubMed2001

Local calibrated bone mineral density in the mandible presented using a color coding scheme.

Calibrated information on bone mineral density (BMD) may be used in dental implantology to measure "bone quality". It can be used to estimate the expected primary implant stability preoperatively and to guide the surgeon in selecting optimum implant types and operation techniques. Using a preoperative dental computed tomography (Dental-CT) scan, all of this information can be obtained without additional examinations and thus without additional X-ray exposure of the patient. In contrast to bone mineral determination in other body regions, local BMD values are important in the jaw bone. Therefore, a regimen where color-coded information on local bone mineralization is superimposed on Dental-CT images is proposed using the original CT volumes as well as reformatted views.

Bone Density↗

PubMed2001

In-vitro assessment of a registration protocol for image guided implant dentistry.

In this study a computer aided navigation technique for accurate positioning of oral implants was assessed. An optical tracking system with specially designed tools for monitoring the position of surgical instruments relative to the patient was used to register 5 partially or completely edentulous jaw models. Besides the accuracy of the tracking system, the precision of localizing a specific position on 3-dimensional preoperative imagery is governed by the registration algorithm which conveys the coordinate system of the preoperative computed tomography (CT) scan to the actual patient position. Two different point-to-point registration algorithms were compared for their suitability for this application. The accuracy was determined separately for the localization error of the position measurement hardware (fiducial localization error-FLE) and the error as reported by the registration algorithm (fiducial registration error-FRE). The overall error of the navigation procedure was determined as the localization error of additional landmarks (steel spheres, 0.5 mm diameter) after registration (target registration error-TRE). Images of the jaw models were obtained using a high resolution CT scan (1.5 mm slice thickness, 1 mm table feed, incremental scanning, 120 kV, 150 mAs, 512 x 512 matrix, FOV 120 mm). The accuracy of the position measurement probes was 0.69 +/- 0.15 mm (FLE). Using 3 implanted fiducial markers, FRE was 0.71 +/- 0.12 mm on average and 1.00 +/- 0.13 mm maximum. TRE was found to be 1.23 +/- 0.28 mm average and 1.87 +/- 0.47 mm maximum. Increasing the number of fiducial markers to a total of 5 did not significantly improve precision. Furthermore it was found that a registration algorithm based on solving an eigenvalue problem is the superior approach for point-to-point matching in terms of mathematical stability. The experimental results indicate that positioning accuracy of oral implants may benefit from computer aided intraoperative navigation. The accuracy achieved compares well to the resolution of the CT scan used. Further development of point-to-point/point-to-surface registration methods and tracking hardware has the potential to improve the precision of the method even further. Our system has potential to reduce the intraoperative risk of causing damage to critical anatomic structures, to minimize the efforts in prosthetic modelling, and to simplify the task of transferring preoperative planning data precisely to the operating room in general.

Algorithms↗

PubMed2001

[A simple method for estimating effective dose in dental CT. Conversion factors and calculation examples for a clinical low dose protocol].

PURPOSE: An easily applicable method to estimate effective dose including in its definition the high radiosensitivity of the salivary glands from dental computed tomography is presented. Effective doses were calculated for a markedly dose reduced dental CT protocol as well as for standard settings. Data are compared with effective doses from the literature obtained with other modalities frequently used in dental care. METHODS: Conversion factors based on the weighted Computed Tomography Dose Index were derived from published data to calculate effective dose values for various CT exposure settings. RESULTS: Conversion factors determined can be used for clinically used kVp settings and prefiltrations. With reduced tube current an effective dose for a CT examination of the maxilla of 22 microSv can be achieved, which compares to values typically obtained with panoramic radiography (26 microSv). A CT scan of the mandible, respectively, gives 123 microSv comparable to a full mouth survey with intraoral films (150 microSv). CONCLUSION: For standard CT scan protocols of the mandible, effective doses exceed 600 microSv. Hence, low dose protocols for dental CT should be considered whenever feasable, especially for paediatric patients. If hard tissue diagnoses is performed, the potential of dose reduction is significant despite the higher image noise levels as readability is still adequate.

Calibration↗

PubMed2001

Lingual vascular canals of the mandible: evaluation with dental CT.

PURPOSE: To evaluate whether dental computed tomography (CT) can depict the frequency, diameter, position, and direction of vessels entering the mandible through lingual bone canals. MATERIALS AND METHODS: Thirty-two consecutive patients underwent preimplantation CT of the lower jaw and examination for the presence, number, location, diameter, and direction of lingual canals entering the mandible. In addition, three cadaver mandibles were investigated with dental CT and subsequently dissected to confirm the CT findings. RESULTS: All patients demonstrated at least one lingual vascular canal, and 20 (63%) had multiple (two to five) canals. The typical lingual canal locations were the midline of the mandible and the premolar region. The mean diameter of the lingual canals was 0.7 mm +/- 0.3 (SD) (range, 0.4--1.5 mm) in the midline and 0.6 mm +/- 0.2 (range, 0.3--1.2 mm) in both premolar regions of the mandible. Examination results in the three cadaver mandibles confirmed the CT findings in those mandibles. CONCLUSION: Dental CT can depict the occurrence, position, and size of the lingual vascular canals of the mandible. Radiologists should be aware of this anatomic feature and its possible implications.

Adolescent↗

PubMed2001

Detection of the mandibular canal via shaded surface display and multiplanar reconstruction of CT data.

The purpose of this study was to evaluate the sensitivity of conventional two-dimensional (2D) multisection images (multiplanar rendering, MPR) and registered three-dimensional (3D) shaded surface images (shaded surface display, SSD) of standard axial computed tomography (CT) data for detecting the mandibular canal (MC) in the lower jaw of 136 patients. The patients, who had different indications for mandibular CT, were examined using standard axial CT scanning. Two post-processing programs were used for 3D visualization of the data sets. The cross-sectional rendered images and the shaded surface 3D images were graded for detection of the MC, the presence of artefacts, overall quality and clinical relevance. A 3D display of the MC was achieved using the MPR technique in 100% with high image quality. The surface rendered display depicted the MC in 80%. Artefacts markedly degraded the 3D displays obtained using the surface rendering technique; thus, SSD is an inappropriate technique for imaging the entire MC without manual segmentation. MPR-CT improves the sensitivity of CT imaging in the detection of the MC with very little time needed for post-processing compared with the SSD method. This post-processing modality should, therefore, be considered for serial studies of patients undergoing dental CT. The sensitivity of the MPR method is even superior to the standard axial CT slices.

Adolescent↗

PubMed2000

Alternative to the median region of the palate for placement of an orthodontic implant.

Tooth-borne anchorage may be one of the greatest limitations of modern orthodontic treatment, because teeth move in response to forces. Previous investigators have placed temporary implants in the median-sagittal palate in order to establish maximum anchorage. This area, however, may be characterized by relatively low vertical bone support. The aim of this study was therefore to find an alternative palatal implant site which offers a higher amount of bone support. This study comprised 22 patients wishing for maximum anchorage underwent presurgical diagnostic evaluation by means of low-dose dental CT. The measuring results regarding vertical bone volume and the position of the neighbouring tooth roots were used as the basis for further treatment. The statistical data analysis indicated an area suitable for implant placement in the group of patients examined. This area was located 6 to 9 mm posterior to the incisive foramen and 3 to 6 mm paramedian, under avoidance of the mid-palatal suture. The patients showed such a great range of variation in vertical bone volume that a preoperative diagnostic evaluation also seems to be recommendable when very short implants are used in order to avoid perforations of the lower nasal duct.

Adolescent↗

PubMed1999

[Conventional dental radiography and future prospectives].

Until recently, conventional dental radiology was performed by dentists and orofacial surgeons. Due to the rapid development of radiological technique, the demand of radiological advice is increasing. The radiologists see more and more dental patients in their daily routine. The aim of this article is to give an overview on established dental radiology and a glimpse into the future. Conventional dental radiology and digital radiography are presently in use. Intraoral technique comprises dental films, bite-wing views and occlusal radiographs. Panoramic views and cephalometric radiographs are done with extraoral technique. Digital radiography lacks all processes in behalf of film development. It leads to dose reduction and enables image manipulation.

Cephalometry↗

PubMed1999

[Magnetic resonance tomography in dental radiology (dental MRI)].

PURPOSE: To demonstrate the usefulness of Dental-MRT for imaging of anatomic and pathologic conditions of the mandible and maxilla. METHODS: Seven healthy volunteers, 5 patients with pulpitis, 9 patients with dentigerous cysts, 5 patients after tooth transplantation and 12 patients with atrophic mandibles were evaluated. Studies of the jaws using axial T1- and T2-weighted gradient echo and spin echo sequences in 2D and 3D technique have been to performed. The acquired images were reconstructed with a standard dental software package on a workstation as panoramic and cross sectional views of the mandible or maxilla. RESULTS: The entire maxilla and mandibula, teeth, dental pulp and the content of the mandibular canal were well depicted. Patients with inflammatory disease of the pulp chamber demonstrate bone marrow edema in the periapical region. Dentigerous cysts and their relation to the surrounding structures are clearly shown. After contrast media application marked enhancement of the dental pulp can be found. CONCLUSION: Dental-MRT provides a valuable tool for visualization and detection of dental diseases.

Diagnostic Imaging↗

PubMed1999

[Dental CT in the planning of surgical procedures. Its significance in the oro-maxillofacial region from the viewpoint of the dentist].

Dental computer assisted tomography (Dental CT) represents a valuable addition to the diagnostic spectrum for planning oral and maxillofacial surgery. High resolution CT and specially designed computer software allow representation of the jaws in different planes that are easy to match. They further allow the display of very small structures relevant to oral surgical interventions and reveal their spatial relationship in three dimensions. Thus communication between dentists and radiologists may be intensified and supported by usage of modern telecommunication systems. Dental CT is indicated, when clinical and conventional radiological techniques will not allow exact interpretation of the situation. It is modern oral implantology that primarily benefits from computer software enabling the assessment of surgical sites in the presurgical phase. Such planning was not yet possible using two dimensional radiographic techniques. The dental-implantological part expects from radiography sharply defined contours of the external bony contours and the mandibular canal, exactly defined relation between slices and planes, no distortion in the orthoradial planes, tools for reliable measurements of distances, angles and volumes, possibility to transmit pictures electronically or on hardcopy without loss of quality.

Humans↗

PubMed1999

[Teleradiology in dentistry].

Teleradiology is a means of electronically transmitting radiographic patient images and consultative text. This offers a new way to communicate with other radiologists and transferring clinicians. Different applications of teleradiology, such as on-call services for emergency departments or rural regions, as well as expert consultation (second opinion) already have been realized. Especially in concern of dental radiography, analog (film-based) imaging gets progressively replaced by digital imaging. The combination with ultrafast data transfer offers an increasing efficacy in diagnosis and therapy, acceleration of communication and new means of quality assessment in patient care. Various applications of teleradiology concerning dental medicine are discussed.

Humans↗

PubMed1999

Virchow-Robin spaces in childhood migraine.

Virchow-Robin spaces (VRS) are pia-lined extensions of the subarachnoid space which surround penetrating arteries as they enter the brain on its surface. Using high-resolution MRI, which shows small penetrating arteries, we studied a possible association of accentuated VRS in children with tension-type headache (TTH) or migraine. We studied 58 children aged 3-14 years (mean 10.8 years) with a clinical diagnosis of migraine (31) or TTH (27), who underwent cerebral MRI, and 30 headache-free patients of the same age (mean 10.2 years) and 30 adult migraineurs with postpubertal onset of symptoms, who served as controls. The images were reviewed for structural abnormalities in the regions of the small penetrating arteries. Accentuated VRS were found in 61% of the children with migrainous headaches and in 22% of children of those with TTH. Prominent VRS were seen in 27% of the control children and in only 13% of the adults. Small infarcts and gliosis were rare in children with or without headache, but were seen in 30% of the adult migraineurs. Our findings show that accentuated VRS are significantly more common in children with migraine than in those with TTH or headache-free controls. Detection of accentuated VRS may therefore enhance differential diagnosis of primary headaches in children, contributing to an improvement in management.

Adolescent↗

PubMed1999

[Occult fractures of the wrist joint: high resolution image magnification roentgen versus MRI].

PURPOSE: To compare the diagnostic value of high definition macroradiography and MRI in patients with the suspicion of occult wrist fractures. MATERIALS AND METHODS: In a prospective study, 23 patients with clinically suspected wrist fractures and normal initial plain radiographs underwent high resolution macroradiography and MR imaging shortly after trauma. Macroradiographs were taken with a microfocus tube using an anode of 0.03-0.3 mm providing a 4x magnification of the wrist, which was obtained in 4 projections. MR images were performed on a 1.0 T MR unit in coronal planes using T1 weighted SE, T2.-weighted 3D GE, and Turbo-STIR sequences. Follow-up radiographs after 6 weeks were used to confirm the diagnosis of a primary occult wrist fracture. RESULTS: Macroradiography depicted 5 wrist fractures: 4 fractures of the scaphoid bone and 1 fracture of the capitate bone. MRI demonstrated 11 fractures (one of them false-positive): 9 fractures of the scaphoid bone and two fractures of the capitate bone. Using macroradiography, the sensitivity for the detection of occult fractures of the wrist was 50% with a specificity of 100%, using MRI the sensitivity was 100% with a specificity of 92%. CONCLUSION: MRI seems to be superior to high resolution macroradiography in the detection of occult scaphoid fractures and thus is recommended in the management of patients with clinically suspected scaphoid fractures not evident on initial plain films.

Adolescent↗