PubMed Health⌕ Search

Biomedical subjects

A Gaik

Publications and source records attributed to A Gaik.

10 recordsLinked to original sources
PubMed1992

[Reactivity of pulmonary mast cells and peripheral blood basophils in patients with sarcoidosis and bronchial asthma].

We have studied the sensitivity of pulmonary mast cells and blood basophils in patients with sarcoidosis and bronchial asthma. The cells were induced in vitro with anti-IgE. The histamine releasing from mast cells and basophils was high in both examined groups of patients. The histamine releasing from mast cells in patients with sarcoidosis was 27.8-47.1% and in asthmatic patients 42.8-58.9%. The histamine releasing from basophils was 38.2-57.9% and 41.0-62.1%, respectively. The high sensitivity of mast cells of patients with sarcoidosis may suggest that these cells play an essential role in pathology of this disease.

Adult↗
PubMed1991

[Incidence of pulmonary tuberculosis in the Lódź province among persons in contact with tuberculotic patients].

The results of an analysis on new cases of pulmonary tuberculosis from contacts with sputum positive tuberculosis are discussed. In subjects with contacts with sputum positive tuberculosis the incidence rates were 16 fold higher in comparison with the general population. In patients that reported contacts with sputum negative tuberculosis the incidence rates were even higher. This contradiction can be explained by the quicker hospitalization in the first group of patients thus terminating contacts.

Disease Reservoirs↗
PubMed1988

Sensitivity of human pulmonary mast cells obtained by bronchoalveolar lavage to immunological and nonimmunological histamine releasers.

We have studied the sensitivity of human pulmonary mast cells to some immunological and nonimmunological histamine releasers. The pulmonary mast cells were obtained by bronchoalveolar lavage (BAL) of nonasthmatic patients. Mast cells constituted about 1% of total cell population and were morphologically intact. These cells were highly sensitive to the challenge with anti-human IgE. They responded to calcium ionophore A23187, polymyxin B and concanavalin A, however the magnitude of histamine release was low. BAL mast cells were unresponsive to the compound 48/80.

Antibodies, Anti-Idiotypic↗
PubMedDate not supplied

Histamine release from human pulmonary mast cells induced by bacterial antigens.

Antigens of four bacteria (Staphylococcus aureus, Haemophilus influenzae, Streptococcus viridans, Branhamella catarrhalis) were tested for their ability to release histamine from human pulmonary mast cells recovered by means of bronchoalveolar lavages. For the sake of comparison the action of bacterial antigens on human mesenteric and adenoidal mast cells obtained by enzymatic dispersion of the tissues was studied. BAL mast cells released histamine in response to all studied bacterial antigens. Haemophilus influenzae antigens were the most effective histamine releasers. From among three populations of human mast cells pulmonary mast cells were the most sensitive to the challenge with bacterial antigens. Mesenteric mast cells were markedly more reactive than adenoidal cells. Adenoidal cells had low sensitivity to bacterial antigens.

Adenoids↗