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Biomedical subjects

A Galeone

Publications and source records attributed to A Galeone.

22 records · Page 2Linked to original sources

Synthesis of 5-methylamino-2'-deoxyuridine derivatives.

Reductive amination of 3',5'-O-(tetraisopropyldisilyloxane-1,3-diyl)-2'-deoxy-5-formyluridine with several aliphatic and aromatic amines, in various solvents, is described. In the case of aliphatic amines, the expected C-5 substituted methylamino pyrimidine nucleosides are formed along with by-products deriving from opening of the pyrimidine ring. Relative amounts of the by-products depend upon the polarity of the solvent employed.

Amines↗

[Metabolic therapy of cardiopathies, based on the biochemical physiopathology of the myocardium].

An updated and systematic account is given of cardiometabolic therapy by one who was among the first to investigate the biochemical pathology of the heart and the rational employment of biological substance in cardiological management. It is preceded by an explanation of the biochemical physiology of the myocardium and the metabolic changes associated with cardiac damage, and with heart failure in particular. The practical importance, effects and limits of metabolic cardiotherapy are assessed and its main fields of utilisation in current medical and cardiological practice are illustrated in the light of personal experience.

Adenosine Triphosphate↗

[Cryoglobulinemia, hemorrhagic vasculitis skin changes in hepatopathy].

Cryoglobulins in the blood of patients with liver diseases may be associated with immunologically induced cutaneous vasculitis and haemorrhage. A personal case of chronic cirrhogenic liver disease with progression to liver insufficiency is presented. The picture included IgG, IgA and IgM cryoglobulinaemia and palpable purpura. The main features of primary and secondary or symptomatic cryoglobulinaemia are described, and an account is given of the mostly recent literature on the association between cryoglobulinaemia and liver diseases. Its pathogenesis and possible forms of treatment are also discussed.

Acute Disease↗