[Incidence of seroconversion for the human immunodeficiency virus in non-hemophiliac patients receiving low doses of prothrombin complex factors].
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Blood Coagulation Factors↗
Biomedical subjects
A García Aranda
Publications and source records attributed to A García Aranda.
[Hemophilia and blood derivatives: past and future].
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Acquired Immunodeficiency Syndrome↗
[Infectivity by HIV of different blood products used in Aragon].
In our region, prevalence of anti-HIV antibodies among hemophiliacs B (83.3%) is higher than among hemophiliacs A (47%), as reported in other spanish communities and contrary to other countries, were the opposite phenomenon has been observed. This seems to be due to the volume of hemo-derivatives received, rather than to their different infectivity, as it has been suggested sometimes. In order to assess this infectivity, independently of doses, we have studied two groups of patients, hemophiliacs A transfused with factor III and non-hemophiliacs who had received concentrate of prothrombinic complex factors (CPCF), in doses lower than 10,000 units. Both groups were transfused during the period when seroconversions were observed in our area (1981-1985) and we demonstrated that the difference between their prevalences of anti-HIV antibodies was not statistically significant.
Blood Coagulation Disorders↗
[Spleen abscess].
3 cases of splenic abscess (SA), all of them with similar clinical findings; abdominal pain, liver and splenic enlargement and leukocytosis, are presented. The diagnosis was suspected by abdominal ultrasound and confirmed by CTR. We focused the interest on the etiopathogenesis, diagnosis and the rareness of the bacteria isolated: Salmonella group D (two cases) and Bacteroides Fragilis.
Abscess↗
[Ungual pigmentation in patients with AIDS treated with zidovudine].
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Acquired Immunodeficiency Syndrome↗
[Hemophagocytosis and undifferentiated carcinoma of the lung].
Hemophagocytosis (HP) constitutes a valuable sign in the diagnosis of a number of hematologic diseases such as malignant histiocytosis (MH). It has also been described in the course of hematologic neoplasias being extremely rare in solid tumors. We present the case of a patient with pancytopenia, hepatomegaly, skin lesions and rapidly fatal evolution in whom the finding of HP in bone marrow arouse the suspicion of a MH. The post mortem study revealed the existence of undifferentiated lung carcinoma with a high degree of invasiveness, not finding histiocytic proliferation. The cases in the literature of the association of HP with non hematological neoplasias are revised as well as its possible pathogenic mechanisms. We conclude that MH needs to be considered as a non specific finding and that exhaustive cytochemical studies are necessary for the correct identification of the phagocytic cell.
Aged↗
[Pancreatitis in infants with a clinical diagnosis of septicemia].
Considering the possibility that during septicemic processes, pancreatitis could develop, 10 infants were studied when the clinical diagnosis of septicemia was established. With this purpose, the clinical manifestations present in the patients were recorded and the activities of serum amilase and lipase were determined at 24 hour intervals during the first three days and these studies were repeated on the 5th and 7th days. The results showed an abnormally high serum lipase activity, especially in 6 of the 10 infants. The amilase was found within normal limits with a tendency to drop in certain cases. This information suggest the presence of acute pancreatitis in some of the subjects studied.
Acute Disease↗