PubMed Health⌕ Search

Biomedical subjects

A García Curiel

Publications and source records attributed to A García Curiel.

15 recordsLinked to original sources
PubMed1999

[Septic paniculitis and 67Ga scintigraphy].

A 50 year-old patient presenting septicemia, septic panniculitis from Staphylococcus aureus and skin lesions on the buttocks, thighs and left arm was referred to the Nuclear Medicine Service, with a suspected underlying osseus problem. A whole body scan with 67Ga revealed generalized disease of the soft tissues with no bone involvement. Gallium was used for the monitor of the evolution of the lesions, since this is a good indicator of the treatment effectiveness. In this case, the use of nuclear techniques was fundamental for diagnosing the spread and evolution of the lesions until they were cured (cured being considered as when there is no gallium uptake by the lesions, months prior to this stage).

Anti-Bacterial Agents↗
PubMed1998

[Resistant Streptococcus pneumoniae].

Streptococcus pneumoniae is a common pathogen in children that in recent years has shown a progressive rise in resistance to the usual antibiotics and also to the new third generation cephalosporins. We report a review of Streptococcus pneumoniae strains isolated at our hospital from pediatrics patients in whom we observed an increased incidence of resistance to cefotaxime significantly related with the rise in resistance to penicillin. The resistance of penicillin-resistant strains to various antibiotics was analyzed and the following results were obtained: cefotaxime, 0% susceptible, 83% intermediate and 17% resistant; erythromycin, 16,7% susceptible, 8,3& intermediate and 75% resistant; vancomycin, 100% susceptible; chloramfenicol, 16,7% susceptible and 83,3% resistant; and cotrimoxazole, 100% resistant.

Child↗
PubMed1994

[Anatomoclinical and diagnostic characteristics of thyroid carcinoma. Study of 126 cases].

A retrospective review was conducted among 126 patients treated for thyroidal carcinoma--86 papillary, 31 follicular, 4 anaplastic, 1 lymphoma, and 4 non-familiar medullary--in our area between 1979 and 1992. Diagnostic and clinical findings obtained were evaluated along with those from physical examinations, imaging techniques (i.e., echography and gamma spectrometry), and histological study (i.e., fine needle puncture-aspiration and intra-operatory biopsy). The majority (88 cases) presented a hard node or one of elastic consistency, while in 34 cases, there was a diffuse or nodular increase. Only four patients manifested a normal thyroid in the physical examination. A 2.4% had a normal gammagraphy, 70% presented a cold node, 1.6% an alient node, and there was evidence of heterogeneous uptake in 23.7%. In the echography study, 63.3% were noted as being solid nodes, 11.4% as cysts, and 24% as mixed. The sensitivity of the fine needle puncture-aspiration was 76.4% and 66.6% for intraoperative biopsy.

Adult↗
PubMed1993

[Treatment of hyperthyroidism from Graves-Basedow's disease].

The Graves's Disease is the most frequent cause of hyperthyroidism. Currently, there is a lack of consensus with respect to the therapeutical role played by synthetic antithyroids, radioactive iodine and surgery. In order to study in depth this issue, we have analyzed the results of the therapy administered to 217 patients with Graves's Disease: 96 were treated with synthetical anti-thyroids, 46 with surgery and 75 with radioactive iodine. After twelve months of therapy with synthetic antithyroids, remission of the disease was observed in 64 patients (67%); the only factor predicting such remission was the absence of ophthalmopathy (p < 0.05); all 64 patients were followed-up during 12 months, detecting the recurrence of hyperthyroidism in 33 of them. Such recurrence is predicted by the serum levels of thyroid hormones before the administration of the therapy (p < 0.001). On the contrary, in patients treated with surgery or radioactive iodine, hyperthyroidism was controlled in 91% and 100% of them, respectively. Given the evolution of patients with Graves's Disease treated with synthetic antithyroids, we suggest the use of a more aggressive approach for the management of these patients.

Adolescent↗
PubMed1980

[Antibiotic sensitivity, serology and typing by pyocine in 154 cultures of Pseudomonas aeruginosa (author's transl)].

Pseudomonas infections continue to be an important problem in the hospital environment. Serious infections are always invariably associated with severe underlying conditions or with diminished host resistance. The increasingly resistance of strains and hospital epidemics favour the organism prevalence. During 1978, Pseudomonas aeruginosa was isolated in 154 cultures from a variety of biological samples in the hospital. Tests of biochemical identification, serological typing, and typing by pyocine production were carried out. Susceptibility to aminoglycosides and beta-lactamic antibiotics was also tested. Serological study demonstrated a higher incidence of 4 and 11 serotypes; 69.4 percent corresponded to type I when typing by pyocine production was carried out. No relationship between serotypes and pyocine-types has been found. Ticarcillin showed a greater activity than carbenicillin (minimal inhibitory concentration less than or equal to 16 micrograms/ml). Amikacin, tobramicin, sisomicin and gentamicin inhibited 83.7 percent, 73.6 percent, 70.7 percent and 69.4 percent of the isolated strains, respectively.

Aminoglycosides↗
PubMed1979

[Determination of endotoxemia by means of the Limulus test in patients with septicemia (author's transl)].

The Limulus test was applied to determine bacterial endotoxemia in 42 patients suspected of having septicemia. Hemocultures were practiced simultaneously. A comparative study is made of the two presently most commonly recommended tests for neutralizing the factors inhibiting the endotoxin-amebocyte reaction. According to our results the dilution of plasma in isotonic saline solution is preferable; we obtained a sensitivity of determination of 0.0001 micrograms of E. coli endotoxin per ml of plasm. Seventeen cases of bacteriemia were diagnosed, only one of which with sepsis due to Serratia marcescens responded positively to the limulus test. The test was positive in three of the remaining 25 patients. Two of them had liver failure. The basic role that liver failure plays in the high level of endotoxin in the blood is discussed. The prognostic value of this test and the low correlation between bacteremia and endotoxemia are also commented on

Endotoxins↗
PubMedDate not supplied

[Microbial growth in parenteral nutrition. II. Effects of osmolality].

Study on the behaviour of five microorganisms in different formulations of Parenteral Nutrition (PN) different from each other with regard to osmolarity. The organisms investigated were Staphylococcus aureus (ATCC (12600), Bacillus subtilis (ATCC 6051), Pseudomonas aeruginosa (ATCC 9027), Enterobacter cloacae (ATCC 13047) y Candida albicans (LSH 3156 D). It was observed no direct relation between microbial growth and osmolarity in PN. C. albicans showed the best growth in all the formulations tested, followed by E. Cloacae. The number of the other microorganisms is reduced, and in general, except B. subtilis grow or are reduced in a lesser extension when the glucose solutions added are at 30 or 40%.

Bacteria↗
PubMedDate not supplied

[A microbial growth study in parenteral nutrition].

Study on the behaviour of five microorganisms in different formulations of parenteral nutrition (PN) different from each other with regard to the presence or absence of lipids and the addition of vitamins or oligoelements. The bacteria investigated were Staphylococcus aureus (ATCC 12600), Bacillus subtilis (ATCC 6051), Pseudomonas aeruginosa (ATCC 9027) and Enterobacter cloacae (ATCC 13047), as well as Candida albicans (LSH 3156 D). It was observed that C. albicans grew well in all types of PN tested, S. aureus and E. cloacae showed growth in the formulations containing lipids, whereas in those lacking lipids, the number of microorganisms remained practically uniform. P. aeruginosa remained essentially constant throughout the study and in all mixtures and B. subtilis was reduced with regard to the number of feasible organisms, due to the formation of spores. Finally, the addition of vitamins or oligoelements did not appear to determine a particular model of evolution in any of the species studied.

Bacteria↗
PubMedDate not supplied

[Bacteriuria caused by Streptococcus pneumoniae].

Four hundred fifty one urine samples from patients with renal transplant and 2,943 from nontransplanted patients were evaluated. Streptococcus pneumoniae grew in 22 samples from the transplanted group (4.9%) and in 24 from the nontransplanted group (0.8%) (p less than 0.001). The number of isolated CFU/ml was usually low, with mean values of 5.4 x 1,000 CFU/ml and 2.8 x 1,000 CFU/ml in both populations, respectively; 47.8% of strains were resistant or moderately sensitive to penicillin, and 56.5% and 60% were resistant to co-trimoxazole and norfloxacin, respectively. All were sensitive to nitrofurantoin and rifampin.

Anti-Bacterial Agents↗