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Biomedical subjects

A García

Publications and source records attributed to A García.

At least 433 records · Page 24Linked to original sources
PubMed1984

[Fever of unknown origin having a neoplastic etiology].

Fifty three patients having fever of unknown origin according to the criterion of Petersdorf and Beeson were studied. Malignant tumors were found to be the cause in 21 per 100 of the cases. The authors indicate the time required to make an etiologic diagnosis, and the procedures employed for it.

Adolescent↗
PubMed1983

The accuracy of medical certifications of cancer deaths and of cancer diagnosis in the municipal area of Barcelona in 1979.

Death certificates containing a diagnosis of cancer concerning residents of the municipal area of Barcelona were matched against their clinical records to assess the accuracy of medical certifications of cancer death. Out of 2,945 cancer deaths, medical records were available in 1,557 (53%). Both documents were in agreement in 81% of the cases. Information on quality of cancer diagnosis was collected by considering the best evidence available derived from the techniques used. Histology of the primary was present in 67% of the cases. Histology of a metastatic deposit or positive cytology was the best evidence in 10% and other techniques -clinical, X-Ray or laboratory tests- were the best method used in 23%.

Death Certificates↗
PubMedDate not supplied

Evaluation of the toxicity of several heavy metals by a fluorescent bacterial bioassay.

This new bioassay determined the toxicity of chemical compounds dissolved in water by measuring the degree of inhibition of the ultraviolet light-stimulated fluorescence of Escherichia coli in a culture medium in which 4-methylumbelliferyl beta-D-glucuronide was the only carbon source. Inhibition produced by one of five heavy-metal salts (Cd2+, Cr6+, Hg2+, Pb2+ or Zn2+) was the end-point and comparison standard to determine the EC50 and minimum effective concentration (MEC) that produced a decrease of E. coli growth rate, increased doubling time and percentage inhibition and reduced numbers of generations; all these values were derived from the fluorescence signals. Only Cr6+ and Hg2+ at two concentrations (0.25 and 0.5 mg l-1) almost completely inhibited this E. coli strain. All toxicant concentrations tested produced at least partial inhibitions of growth; Cr6+, Hg2+ and Cd2+, in that order, were most toxic, and Pb2+ the least. Zn2+ gave higher EC50 values at 3 h of incubation than at 4 h. The method was simple, rapid and inexpensive and would permit a large number of samples to be tested quickly.

Biological Assay↗