Biomedical subjects

A Gazca Aguilar

Publications and source records attributed to A Gazca Aguilar.

5 recordsLinked to original sources

PubMed1995

[Asthma and pregnancy].

Asthma is among the diseases that may complicate pregnancy. Asthma affects up to 4% of the pregnant women. Uncontrolled asthma may impair the proper oxygenation of both mother and child. According to asthma severity clinical manifestations may be unapparent or apparent requiring hospital treatment. It is necessary that pregnant asthmatic woman check daily the peak-flow by portable peak-flow meters. The asthma pharmacological treatment should consider the changes in the physiology of the pregnancy, such as low albumin and carrier proteins for the drugs inducing high levels of free active drugs. This point is important for theophylline, besides the low drug clearance. Bronchodilator should be used as they are required, using the inhaled forms, as well as short term corticoid courses. The goal of the treatment is to control the symptoms, avoid relapse and keep the ventilatory function close to the normal, in order to achieve a satisfactory state of the mother and the children.

Adrenal Cortex Hormones↗

PubMedDate not supplied

[Antihistaminics].

The antihistamines are drugs who compete for the histamine receptor H-1, blocking the liberation of autacoid mediators, that is the reason for their action in allergic diseases. It's important to know the pharmacodynamics and pharmacokinetics of these drugs in order to choose the best one for the patient, looking for the ones who have less side effects and work better. We show a summary of the principal antihistamines, their actions and side effects.

Eicosanoids↗

PubMedDate not supplied

[Comparison of 2 skin test methods for the diagnosis of allergic diseases].

Diagnosis of allergic diseases is realized by clinical history and cutaneous tests to determine the causative allergen. As several cutaneous test exist we consider necessary evaluate sensibility and specificity of epicutaneous (EP) and intradermic (ID) test. All open, prospective transversal study was carried out. The study included 45 patients suffering asthma, allergic rhinitis or both. The patients underwent both kind of test, with 10 allergens: Dermatophagoides pteronyssinus, Fraxinus, Ligustrum, Quereus, Schinus, Phleum, Amaranthus, Ambrosia, Artemisa. Alternaria and Hormodendrum. The mean age was 12 years. No difference was found comparing positive results for tree, grass, weed and molds allergens using both test. Instead for Dermatophagoides pt EP had 92.5% of sensibility and 100% of specificity, mean while ID has 100% of sensibility and 96.6% of specificity. We conclude that ID test have greater sensibility and EP have greater specificity, we recommend use EP for first instance.

Adolescent↗

PubMedDate not supplied

[Mastocytosis in children. Report of 3 cases].

The mastocytosis is a disease characterized by an increase in mast cell number, and may present in childhood. It is classified as cutaneous or systemic mastocytosis. Cutaneous mastocytosis generally is selected in childhood. It is important to be aware of systemic complications. Systemic mastocytosis is adult-onset and its clinical presentations is caused by histamine, leucotrienes, prostaglandins and other mediators' release. The treatment is directed at symptomatic relief. Several cases are reported at Hospital Infantil de México Federico Gómez. Only 3 cases are presented of these benign child-onset diseases.

Age of Onset↗

PubMedDate not supplied

[Asthma physiopathology].

Bronchial asthma is a very common disease but often the diagnosis and treatment is not done correctly. The physiopathology is very complex in which are involved neuroimmune mechanism with imbalance between sympatic-parasympatic system, and the other pathways including non adrenergic non colinergic and neuropeptide factors. The immunologic participation with a high level of IgE and the activation of the interleukins, all these together with very active participation of the adhesives, are the responsible for the activations and action of the chemical substances who are the origin of the bronchospasm and inflammation.

Asthma↗