PubMed HealthSearch

Biomedical subjects

A Geoffray

Publications and source records attributed to A Geoffray.

34 records · Page 2Linked to original sources

Ultrasonography and computed tomography for diagnosis and follow-up of pelvic rhabdomyosarcomas in children.

The authors report 18 cases of pelvic rhabdomyosarcomas in children examined at presentation and followed on US and CT. There were 11 boys, 7 girls; tumor location was bladder, prostate or uterus in 12, perineum in 4, buttock in 2. US is good to define tumoral extension within the bladder CT is better to delineate the extension outside the bladder and regional spread to iliac nodes. CT is the only useful examination for perineal tumors. During chemotherapy US can be frequently repeated to appreciate tumoral regression and to give measurement of the mass. Preoperative CT should be performed when tumoral regression seems sufficient to permit complete tumoral excision without pelvic exenteration. Correlation between US and CT and surgical findings proved to be good. US and CT are also very useful in the follow-up when the child has finished treatment as it can demonstrate a local recurrence before clinical symptoms appear. However, post-surgical and post-radiation changes may be difficult to recognize. These aspects are discussed.

Adolescent

[Cancer of the prostate: value of x-ray computed tomography in the preradiotherapeutic evaluation. Apropos of 49 cases reviewed at the Gustave-Roussy Institute].

Fourty nine patients having a prostatic carcinoma had a CT examination. CT should be used only if bone metastasis lack and if a curative treatment is possible. Study of local extension is misleading and ultrasound, especially transrectal, is a better method to appreciate the volume of the tumor. On the contrary, CT detects quite often nodes metastasis which will modify the treatment. If CT is negative, lymphangiogram must be done because it is a more precise method to evaluate the node structure. Percutaneous node biopsy may confirm node metastasis.

Aged

Abdominal and pelvic computed tomography in leukemic patients.

Fifty-two patients with different types of leukemia [27 chronic lymphocytic leukemia (CLL), 10 acute myeloblastic leukemia (AML), eight acute lymphoblastic leukemia (ALL), four chronic myelogenous leukemia (CML), and three hairy cell leukemia (HCL)] had abdominal and pelvic CT. The radiographic features are reviewed to evaluate the role of CT in diagnosis and management of these patients. The highest incidence of lymphadenopathy was observed in CLL followed by HCL and ALL. Other findings included splenomegaly, hepatomegaly, ascites, pleural effusion, microabscesses in liver and kidney, and visceral involvement, i.e. intestine, bladder, and bone.

Adolescent

Cranial computed tomographic abnormalities in leptomeningeal metastasis.

Sixty-four (57.6%) of 111 cancer patients with cerebrospinal fluid cytology positive for malignant cells had cranial computed tomographic (CT) scans within 2 weeks before or after a lumbar puncture. Twenty-two (34.3%) of the 64 had abnormal CT findings indicative of leptomeningeal metastasis: (1) sulcal-cisternal enhancement, (2) ependymal-subependymal enhancement, (3) widened irregular tentorial enhancement, or (4) communicating hydrocephalus. Thirteen (59.6%) of these 22 patients had associated parenchymal metastases. Recognition of leptomeningeal disease may alter the management of patients with parenchymal metastases. Communicating hydrocephalus in cancer patients should be considered to be related to leptomeningeal metastasis until proven otherwise.

Brain

Contribution of computed tomography (CT) in the study of 24 head and neck embryonic rhabdomyosarcomas in children.

Our study of 24 head and neck embryonic rhabdomyosarcomas in children confirms the substantial contribution of CT: -to the diagnosis, by showing the soft tissue mass, the bone destruction especially at the skull base, orbital walls and walls of the maxillary sinuses and intra-orbital or intra-cranial extension, -for the follow-up during treatment, it shows the efficacy of treatment, confirms the diagnosis of complete remission and contributes to an evaluation for recurrence.

Child

[Radiology in the diagnosis of volvulus caused by mesenteric rotation anomaly].

Thirty-eight children were operated on between 1974 and 1979 at the hôpital Trousseau for a volvulus of the small intestine due to an abnormal mesenteric rotation. These children may be classified into 3 groups: (1) peracute volvulus, most often neonatal, with intestinal necrosis, generally lethal; (2) acute volvulus, also neonatal, with a favorable outcome after treatment; (3) chronic volvulus, which may occur at any age and may be symptomatic or not. They carry a risk of acute complication, with possible intestinal necrosis. Radiology plays a part in the diagnosis of such anomalies of rotation complicated with volvulus. Upper gastrointestinal tract opacification with barium sulfate, showing the abnormal position of the duodenojejunal flexure and a corkscrew appearance allows surgical decision, as in all cases, treatment is surgical. It consists of derotation and setting in complete common mesentery position.

Acute Disease

[X-ray computed tomography of cancers of the uterine body (stages I and II). Anatomopathologic correlations. Apropos of 25 cases].

Twenty-five patients with endometrial cancer of body of uterus were examined by CT before and after intravenous administration of contrast medium. Hypodensity was noted before injection and was accentuated after injection in 4 cases, was observed after injection only in 9 and was totally absent in 12 cases. Comparison of findings with results of examination of frozen specimens indicated lack of correlation between size of tumor and depth to which myometrium was invaded, and results of CT imaging.

Adenocarcinoma

[Computed x-ray tomography in the study of 16 undifferentiated epitheliomas of the cavum nasopharyngeal type in children].

CT scans were performed in 16 children with undifferentiated epitheliomas of the cavum nasopharyngis type. The CT scan provided the most precise data during initial investigations, especially clear information being obtained on any intra-orbital or intracranial extension, which may occur without clinical signs. The scan is also a valid method for determining efficacy during treatment, and for the early detection of recurrences.

Adolescent

Extracranial meningiomas of the head and neck.

Extracranial extraspinal meningiomas (less than 1% of all meningiomas) frequently occur in the head and neck. The radiographic findings of extracranial meningioma of the head and neck are not pathognomonic. However, the location of the tumor in the pathway of cranial nerves or adjacent to the skull base, the demonstration of a well circumscribed, solid, enhancing mass by computed tomography, and the faint tumor stain on arteriography should allow the radiologist to make a possible, although not definite, diagnosis of this rare tumor. Detection of possible intracranial extension and involvement of adjacent structures is mandatory before surgery.

Adult