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Biomedical subjects

A Ghersi

Publications and source records attributed to A Ghersi.

2 recordsLinked to original sources

[Value of MRI in the study of hepatocellular carcinoma. Preliminary study apropos of 12 cases].

The authors have tested different MR imaging sequences to detect hepatocellular carcinomas. The most performing is a spin-echo T2-weighted sequence with long TR (1800 or 2000 ms), and three echoes. The first echo, early at 40 ms, may allow an analysis of the vessels, later, at 80 and 120 ms, the two other echoes permit a better visualization of the tumor. With this type of sequence, the method's sensibility is excellent.

Carcinoma, Hepatocellular

[Hemopigmented villonodular synovitis].

Pigmented Villonodular Synovitis (PVNS) in an infrequent tumoral like disease and there are only a few MRI studies published. Concerning our series of five cases compared with the literature, the readers attention is drawn to the etiologies still under debate and to the respective contribution of the different imaging methods. MRI known for its high sensibility, but also for its low specificity in tumoral pathology, has turned out to be, in the case of PVNS, quite remarkable in both regards. The RMI aspect is quite well correlated to the histological structure of this synovial hyperplasia and to its evolution: highly vascular mass at the beginning and then low cellular density stroma, fibrous, with deposition of hemosiderin. In our five cases, as in almost all those previously reported in the literature, MR imaging shows heterogeneous areas of decreased signal intensity on T2 weighted sequences and on two of our cases after administration of gadolinium. Still the same MR aspects can be found in rheumatoid, hemophilic arthritis, as well as synovial chondromatosis, and therefore the clinical background and findings as well as plain films become essential. MR imaging should be the first examination to be undertaken after plain films, leading in most cases to a precise local preoperative assessment.

Female