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Biomedical subjects

A Gilbert

Publications and source records attributed to A Gilbert.

At least 91 records · Page 5Linked to original sources
PubMed1982

[Epiphyseal vascularization during growth. Study preliminary to transplantation].

A study was conducted of 50 cadavers in children and 25 immature dogs to discover more precisely the vascularization of the lower end of the femur and the iliac crest. It was concluded that it is possible to transplant these epiphyses with anastomosis of three pedicles in the same line. It was also concluded that the vascularisation differs before and after the formation of the bony epiphyseal nucleus. The cartilaginous canals which preclude the vascularisation of hyaline cartilage, the formation of the bony nucleus and the nutrition of the germinal layers of the growth plate are described.

Animals↗
PubMed1981

[The place of Gelineau's syndrome (narcolepsy) among diurnal attacks of sleep and somnolence (author's transl)].

A clinical and electroencephalographic study was conducted in 41 patients (25 men and 16 women) complaining of diurnal attacks of sleep, and the results were compared with those obtained in 15 control subjects (7 men and 8 women) of the same age. EEG tracings were recorded during 33 hours in each subject. The total duration of the various phases of nocturnal sleep and the mean duration of each phase were the same in both groups. The incidence of EEG peculiarities, such as short delay in the onset of sleep and in the first stage of desynchronized sleep, and prolonged nocturnal periods of vigilance, was assessed in both groups, but no correlation was found between clinical and electrical data. The three criteria of Gelineau's syndrome (irresistible sleepiness, cataplexy and onset of sleep in desynchronized phase) were present in 35% of the patients.

Adult↗
PubMed1981

Vascular microsurgery in orthopaedics.

Three applications of free vascularised bone grafts are described. Free fibular grafts have been performed in 19 cases of avascular necrosis of the femoral head. The grafts are placed along the anterior femoral neck and into the femoral head with a microvascular anastomosis between the nutrient vessels of the fibula and the anterior circumflex pedicle of the hip. The operative technique is described but the post-operative follow-up is still too short to draw any definite conclusions. This operation has been performed in young patients in whom the only alternative would be a total hip replacement. Free vascularised transfers of iliac crest bone are described for bone defects such as infected non-unions of the tibia with soft tissue and bony loss. Free vascularised fibula grafts have also been employed with cancellous grafting for cystic defects such as fibrous dysplasia and large bone cysts. The use of free vascularised fibula grafts is also described in four cases of congenital pseuodarthrosis of the tibia.

Child↗
PubMed1981

[Revascularization of the femoral head for avascular necrosis (author's transl)].

The authors present an original technique for the treatment of avascular necrosis of the hip. The femoral head is dislocated and the articular cartilage is opened. The necrosed bone is excised and replaced by new cancelous bone. A fibula with the vascular pedicle is then introduced in the femoral head on its anterior aspect, and revascularized by microvascular anastomoses. Nineteen patients have been operated but the follow-up is not long enough. It will take several years before a complete assessment of the technique is possible.

Bone Transplantation↗
PubMed1981

Iron deficiency and behavioral deficits.

In an attempt to investigate the relationship of iron deficiency and mental status, cognitive development and attending behavior were assessed in nonanemic children aged 11 to 13 months who were severely or mildly iron deficient or were iron replete. Using two different approaches to the assessment of cognitive development and an habituation measure as an index of attending behavior, no statistically significant differences could be demonstrated in the overall level of performance between the iron-depleted and the iron-replete children. Isolated differences were demonstrated on a scale that measured fearfulness and on several of the scales that measured sensory areas of interest displayed.

Child Behavior↗
PubMed1980

The histopathology of microlymphaticovenous anastomosis.

Histopathological studies are described on 30 biopsy specimens of lymphaticovenous anastomoses ranging from two days to eight months following operation. Sixteen were patent and 14 were occluded. It was observed that in the non-patent specimens occlusion stemmed from the venous component. The prime determining factor in the success of the anastomosis was the achievement of correct apposition of the cut edges of the vessels, and this was directly dependent on the number and spacing of the sutures as well as the tension applied at their insertion. Correct apposition is more easily achieved with these delicate thin-walled vessels by better visualization afforded by the use of the operating microscope and appropriate instrumentation. The slow rate of repair in this situation is emphasized.

Animals↗
PubMed1979

[Polygraphic study of nocturnal sleep in three degenerative diseases: ALS, oligo-ponto-cerebellar atrophy, and progressive supranuclear palsy].

A polygraphic study of nocturnal sleep was carried out on 12 patients suffering from amyotrophic lateral sclerosis (ALS), 6 patients suffering from olivio-ponto-cerebellare-atrophia (OPCA) and 9 patients suffering from the Steele-Richardson disease (SR). A disturbance of sleep--if it exists--always runs parallel with the course of the disease. No disturbances were registered in the group of patients suffering from ALS, in the OPCA group a specific disease of paradoxal sleep is observed. The sleep disturbances are more global in the group of patients suffering from the SR disease. A particular electrooculogram was taken from the patients from the awakening and from the paradoxal sleep. Respiratory difficulties were registered on certain patients of each of the three groups. These sleep disturbances, registered by the polygraph, were compared with those observed on patients presenting a cortical disease.

Adult↗
PubMed1979

[The effects of gammaglobulins in resistant epilepsies. A preliminary study (author's transl)].

The effect of injections of gammaglobulins 16 Mérieux (1 ml/kg) was studied in 9 patients aged from 1 to 35 years suffering from epilepsy resistant to conventional anticonvulsant treatment. Different types of epilepsy were studied to try to discover a possible indication as a function of the type of epilepsy. Results were assessed according to the patients' behaviour, the frequency and severity of clinical fits, the results of psychological tests, and EEG tracing recorded over long periods of time. Recordings were repeated every 2 to 3 weeks. Favourable results were observed in 7 cases with: --an increased rate of sleeping and waking EEG tracings, --a reduction in the percentage of paroxysms whatever the wakefulness stage, --alterations in the percentages of some sleep stages. The possible mechanisms of action of IgG are discussed.

Adolescent↗