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Biomedical subjects

A Gołebiowska

Publications and source records attributed to A Gołebiowska.

9 recordsLinked to original sources

[Acute nonlymphoblastic leukemia as a secondary malignancy--demonstration of 15 patients].

Among 90,128 patients with malignancies in the years 1976-1989 acute non lymphoblastic leukaemia (ANLL) was diagnosed in 351 patients (0.4%) and in 15 (4.3%) of them ANLL was secondary neoplasm. Secondary ANLL occurred in 10% of all the 148 secondary malignancies observed at that period of time and constituted 6.7% of secondary malignancy in patients with solid tumours and 43% in patients with myeloproliferative syndromes as a first malignant neoplasm. In the treatment of first malignancy radiotherapy was applied in 11 persons, in combination with chemotherapy in 7 of them and chemotherapy alone was given to 4 patients. The appearance of the secondary ANLL was usually preceded by the myelodysplastic syndrome. Morphologically, secondary ANLL belonged mostly to M6 and M4 (8 patients) according to FAB classification. The course of ANLL was fulminant and the disease was completely resistant to the treatment.

Adolescent↗

Epidemiology of butchers' warts.

Studies were carried out in two slaughter-houses in different cities differing in the degree of work automation and, for comparison, in workers of nearby factories of the same two cities. There was a high incidence of warts (49.2%) in a slaughterhouse where the workers had direct contact with animals and meat, while a significantly lower incidence (9%) was observed in a modern slaughterhouse where the work was almost completely automated. The types of human papillomaviruses (HPVs) were similar in warts of butchers from these slaughterhouses and of 63 butchers from various slaughterhouses all over the country. All cutaneous HPVs were present in butchers' warts. The so-called butchers' wart virus HPV-7 was found in about 30% of the butchers from all slaughterhouses. Cell-mediated immunity of the butchers was found to be unimpaired. There was no correlation between the incidence of infection and the frequency of antibodies against HPV-1, HPV-2, or HPV-3.

Abattoirs↗