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A González Navarro

Publications and source records attributed to A González Navarro.

8 recordsLinked to original sources

[Influence of the diet on the development of colorectal cancer in a population of Madrid].

OBJECTIVE: Although the genetic component in colorectal carcinoma (CRC) is well established, some environmental factors, mainly dietary, can favor its development. The objective of this study is to evaluate the relationship between daily consumption of specific food groups and development of CRC. METHODS: We carried out a case-control study in an area of Madrid; 196 patients with diagnosis of CRC with confirmed histology and registered to May 1998 in the Community of Madrid tumor register were included, and they were compared with 196 controls matched by age, sex, and geographical area. All of them filled out a questionnaire with information on diet, substance abuse, physical activity, drugs, and family history of CRC. RESULTS: The logistic regression analysis showed a weakly positive association with meat (OR: 1.02; CI: 1.01-1.04), viscera (OR: 1.12; CI: 1.02-1.23), and sausage (OR: 1.07; CI: 1.03-1.1) consumption, and a modest inverse association with consumption of yogurt (OR: 0.97; CI: 0.95-0.98), tomato (OR: 0.99; CI: 0.98-0.99), strawberries and cherries (OR: 0.97; CI: 0.95-0.99), oranges, grapefruits, and natural fruit juices (OR: 0.99; CI: 0.98-1). CONCLUSIONS: These results are an additional empirical evidence that must be confirmed through prospective studies.

Case-Control Studies↗

Intrathecal opiates for chronic pain in cancer patients.

A total of 20 cancer patients suffering chronic pain were treated with morphine chloride by intrathecal administration through a subcutaneous implanted reservoir. Pain evaluation was done using our INO scale, McGill questionnaire and the visual analogue scale. A morphine intrathecal test was done previously to disclose if this method of administration would be effective. In nearly all patients the initial dose of morphine chloride was 2 mg/day and according to the pain relief the dose was modified if necessary. In 14/20 patients the initial dose was maintained during all treatment until their death. One patient treated during 370 days required a final dose of 6 mg/day. In all patients the analgesia obtained and evaluated with the INO scale was statistically significant using the t-Student (P less than 0.001) with a pretreatment mean value of 12.4 +/- 1.81 (mean +/- sigma) and 6.85 +/- 0.99 (mean sigma) in the final evaluation. The mean period of treatment was 62.8 days (range 10-370 days). Side effects are comparable with those described by others, and respiratory depression did not occur in our series. This method of treatment can alleviate pain in cancer patients not suitable to be treated by other methods, including ablative neurosurgical procedures, permitting home care which can be more comfortable to patients and their families.

Adult↗

[The general criteria and recommendations for the elaboration of programs for the early detection of breast cancer and cervical cancer in Spain. The Working Group for the Early Detection of Breast Cancer and Cervical Cancer].

Cancer screening and primary prevention of cancer are effective strategies to reduce cancer morbidity and mortality. The experience gained in several European countries about breast and cervical cancer has been growing in the last decades. This fact facilitates the adoption of the most convenient strategies to implement screening programmes in Spain. The Spanish Ministry of Health and Consumer Affairs set up a work group of experts and health managers to make recommendations and to define the basic criteria to take into account when planning and implementing these programmes. The article describes those recommendations as well as the priorities to be established regarding the target population, and the strategies to increase efficiency of those programmes. Recommendations were made according with scientific evidences and the current situation and resources in Spain.

Breast Neoplasms↗