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A González Praetorius

Publications and source records attributed to A González Praetorius.

5 recordsLinked to original sources
PubMed2003

[Susceptibility of Streptococcus pyogenes to macrolides and quinolones in Guadalajara, Spain].

We carried out a retrospective study of the susceptibility of 104 Streptococcus pyogenes strains, which were isolated in 2000 and 2001 from clinical samples of different origins, to penicillin, erythromycin, clindamycin, ofloxacin and levofloxacin. The susceptibility testing was performed using the agar difusion method according to the guidelines of the NCCLS. All of the isolates showed susceptibility to penicillin and clindamycin. However, we detected 11 strains that were resistant to erythromycin (10.6%) and 4 strains resistant to ofloxacin (3.8%). We studied the resistance phenotypes of macrolides and lincosamides using erythromycin and clindamycin discs. Nine of the eleven strains that were resistant to erythromycin showed an M phenotype, while the remaining two showed inducible resistance to clindamycin, thus suggesting an MLS(B) inducible phenotype. No strains with constitutive resistance to erythromycin or clindamycin (MLS(B) constitutive phenotype) were identified. While penicillin is still uniformly active against S. pyogenes, in Guadalajara, there are 10.6% strains that are resistant to 14- and 15-atoms macrolides.

Anti-Bacterial Agents↗
PubMed2002

[Incidence and risk factors for hepatitis A in the province of Guadalajara (Spain)].

BACKGROUND: The decrease in the prevalence of hepatitis A in Spain may modify the characteristics of this infection because of the rise in the susceptible adult population. The aim of this study was to determine the incidence of this disease, as well as the epidemiological characteristics and the complications of patients diagnosed in the province of Guadalajara between 1991 and 1999. PATIENTS AND METHODS: The inclusion criterion was the presence of specific IgM together with an increase in alanine aminotransferase concentrations and/or symptoms compatible with acute hepatitis. RESULTS: The mean incidence was 7.13 cases/105 inhabitants. Considerable differences were found between years due to the presence of an outbreak. Most cases occurred in children and young adults. The most frequent risk factor found overall was contact with an infected individual but the distribution of risk factors differed between children and adults. CONCLUSIONS: The decrease in the prevalence of hepatitis A in Spain entails an increase in the susceptible adult population. Consequently, hepatitis A may cease to be a typically pediatric disease and may become one that also affects young adults in whom it may have different characteristics. This consideration should be borne in mind when designing a vaccination strategy.

Adolescent↗
PubMedDate not supplied

[Seroprevalence of three types of hepatotropic virus in a population of adolescents of the province of Guadalajara].

BACKGROUND: Viral forms of hepatitis are one of the most infectious disease groups most often encountered in human pathology, and although most are benign, some can evolve into chronic forms. The purpose of this study is that of ascertaining the prevalence of hepatitis C, Epstein-Barr and human herpesvirus-6 infections among eighth-graders (13-14 years of age) and to related the same to variables regarding the gender and environment (rural or urban) in which they were living. METHODS: Descriptive, transversal study of a representative sample of the eighth-grade population in the province of Guadalajara during the 1998-1999 period. Systematic random sampling layered by gender and school (multi-stage sample format). The rate of specific IgG antibodies was determined using the ELISA technique. RESULTS: A study was conducted of 268 school-age children (46.6% males). The prevalence of Epstein-Barr antibodies was of 73.5% (CI: 67.9%-78.5%); 72% (CI: 64%-80%) among the males and of 74.8% (CI: 67.7%-81.9%) among the females (NS); 65.6% (CI: 57.4%-73.8%) residing in an urban environment and 80.7% in a rural environment (p < 0.05). The prevalence of those who tested positive for the hepatitis virus was that of 0.7%--two individuals, both females, one of whom resided in an urban environment and the other in a rural environment. For herpesvirus-6, the prevalence was of 82.4% (CI: 77.9%-86.9%); 81.5% (CI: 74.7%-88.3%) among the males and of 83.2% (CI: 77.1%-89.3%) among the females (NS), 86.7% (CI: 80.4%-92.2%) residing in an urban environment and 78.5% (CI: 73.1%-86.5%) in a rural environment (p < 0.05). CONCLUSIONS: The prevalence of Epstein-Barr and human herpesvirus-6 and low degree as regards VHC is high, which tallies with the characteristics of the environment and age of the individuals under study.

Adolescent↗