Biomedical subjects

A Gröbe

Publications and source records attributed to A Gröbe.

5 recordsLinked to original sources

PubMed1994

Optimized biosensor for whole blood measurements using a new cellulose based membrane.

We used bacterial cellulose membranes as outer membranes for glucose sensors based upon amperometric detection of glucose oxidase reaction products. We found a long-term stability in 1:10 diluted blood of about 200 h. In comparison a Cuprophan membrane was stable for only 30 h under the same conditions. Comparing the two membranes in undiluted human blood, a similar trend was found in the long-term stability; Cuprophan was stable for only 3-4 h and the glucose sensor with the bacterial cellulose membrane was stable for more than 24 h. In addition, the measuring range of the glucose sensor could be extended up to 170 mM glucose by treating the bacterial cellulose membrane with a polyamide.

Ascorbic Acid↗

PubMed1971

[Morphologic studies on native and synthetic gels. Problems connected with optimal conditions for the preparation of ionotropic gels].

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Animals↗

PubMed1970

Autoradiography in the scanning electron microscope.

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Autoradiography↗

PubMed1968

[Wet impression methods for the electron microscopic study of undried fibres].

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Microscopy, Electron↗

PubMedDate not supplied

Influence of matrix metalloproteinase 9 (MMP-9) on the metastatic behavior of oropharyngeal cancer.

BACKGROUND: The role of the single matrix metalloproteinases (MMPs) in the metastatic process of squamous cell carcinomas (SCC) is still obscure. MATERIALS AND METHODS: The MMP-9 expression was described immunohistochemically in 105 patients (40-79 years of age, mean: 57.84 years; 84 male, 21 female) suffering from orophatyngeal cancer (22x TI, 31x T2, 24x T3, 28x T4) with different neck stages (41x N0, 6x N1, 54x N2, 4x N3 neck). RESULTS: A significant correlation between MMP-9 expression and T stage (p < 0.05), N stage (r = 0.55, p < 0.01) and UICC stage (r = 0.55, p < 0.01) was revealed. Most remarkable was the high MMP-9 expression with simultaneously high UICC stages. CONCLUSION: The results give further indication that MMP-9 plays a role in the metastatic behavior of oropharyngeal SCC. It will be a project for the near future to create a standardized evaluation score of immuno-histological stainings to allow valid comparison of the results and published data.

Adult↗