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Biomedical subjects

A Grüntzig

Publications and source records attributed to A Grüntzig.

At least 55 records · Page 3Linked to original sources

[The percutaneous dilatation of chronic coronary stenoses--experiments and morphology].

Since 1971, percutaneous transluminal angioplasty of peripheral arteries has been performed in 225 patients. There was an overall patency rate of 70-80% after 2 years. Our technique was then adapted and modified to perform coronary dilatation. This was performed successfully in 8 dogs in which selective coronary artery stenosis war induced by silk ligature and secondary inflammatory changes. The technique was then applied to the coronary lesions in postmortal humans and tested in the operating room during A-C bypass to evaluate vessel patency, peripheral debris etc.

Aged↗

[Percutaneous dilatation of experimental coronary artery stenosis- description of a new catheter system].

A technical description of a catheter system is given for percutaneous dilatation of experimental stenosis in small ateries (e.g. left coronary artery). The system consists of two catheters: the first is positioned into the orifice of the small artery and guides the second, double-lumen-dilatation catheter into the artery. During the manipulation ischemia in the peripheral area is prevented by contineous perfusion with oxygenated blood taken from the femoral artery by a roller-pump. The catheter system was tested in canine experiments.

Animals↗

[Experiences with Dotter's percutaneous recanalization of chronic arterial occlusions].

Since 1971 141 patients (mean age 66 years, range 46-85 years) with chronic occlusions of the pelvic (19) and superficial femoral popliteal arteries (122) have been treated by the percutaneous recanalization technique first described by Dotter and Judkins in 1964. Since 1974 we have employed a modification of the original Dotter technique. The occluding material is removed with a double-lumen distensible catheter introduced over a guide wire. Primary success was achieved in 117 (83%) patients. Re-occlusions occurred in 18 patients after 6 months and in 5 patients in the second half of the first year, giving an overall patency rate of 75%. Up to now no further re-occlusions of dilated arterial segments have been observed. Indications for this treatment as compared with vascular surgery are discussed.

Aged↗

[Percutaneous recanalisation of chronic arterial occlusions (Dotter principle) with a new double lumen dilatation catheter (author's transl)].

A modification of Dotter's transluminal recanalisation of stenoses and occlusions of the superficial femoral artery, and of stenoses of the iliac artery, is described. In this procedure the occluding material is compressed not by successive catheters, but by a catheter with a dilatable cover. This catheter consisted originally of a single lumen, but now has double lumen; one lumen accomodates contrast, or a guide wire or a stiff cannula, whereas the second lumen is used for filling the cover and the expandable segment. The procedure is described in detail. Results so far appear satisfactory; they are compared with the results which have been obtained during the last year with the single lumen catheter.

Aftercare↗