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Biomedical subjects

A Granath

Publications and source records attributed to A Granath.

10 recordsLinked to original sources
PubMed1986

Repeated exercise and redistribution thallium-201 scintigrams in patients with myocardial infarction treated with timolol or placebo.

Repeat exercise thallium-201 scintigrams were performed 2 weeks, 3 months, and 6 months in 27 patients following their first myocardial infarction. All patients were treated with timolol or matching placebo, administered intravenously starting within 5 hours of onset of chest pain. The extent of transient perfusion defects in 15 timolol-treated patients increased significantly between 2 weeks and 3 months compared to a decrease in 12 placebo-treated patients (p less than 0.05). Between 3 and 6 months the extent of transient defects did not change in the two groups, and there was no difference between the groups. The extent of permanent defects was not significantly different between the timolol- and placebo-treated patients on any occasion. However, patients in the timolol group had a decrease in permanent defects with time in contrast to patients in the placebo group (p less than 0.05). Thus, early intervention with timolol in the acute phase of myocardial infarction may have consequences for the postinfarction phase, as reflected in repeat thallium-201 scintigrams.

Adult↗
PubMed1980

Stokes-Adams attacks requiring pacemaker treatment in three patients with acute nonspecific myocarditis.

Three patients, aged 16--44 years, with complete heart block in acute myocarditis are reported. The diagnosis of myocarditis was based on the development of transitory repolarization disturbances on the ECG in association with clinical signs of acute infectious disease. All patients were brought to hospital due to repeated Stokes-Adams attacks and demonstrated ventricular asystoles for up to 25 sec. The patients were all successfully treated with temporary intracardiac pacing but one of them later turned out to require a permanent pacemaker. The possibility of differences in localization and in prognostic importance of conduction disturbances between infectious and ischemic myocardial disease is discussed.

Acute Disease↗
PubMed1977

Early work load tests for evaluation of long-term prognosis of acute myocardial infarction.

Exercise tests performed 3 and 9 weeks after acute myocardial infarction in 205 patients were found to give prognostic information on the survival during a follow-up period of 2 to 5 years. The appearance of tachycardia, major ventricular arrhythmias, or anginal complaints during these early exercise tests was thus accompanied by a significantly increased mortality during the observation period. Ventricular arrhythmias disclosed by exercise proved to be of higher prognostic significance than those recorded at rest on the same occasions. The usefulness of early exercise tests in the evaluation of the response to antiarrhythmic treatment after acute myocardial infarction as well as of the prognostic importance of the effects was documented in a smaller series of patients.

Acute Disease↗
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Education, Nursing, Continuing↗