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Biomedical subjects

A Grinspoon

Publications and source records attributed to A Grinspoon.

4 recordsLinked to original sources

Increased serotonin 5-HT2 receptor binding on blood platelets of suicidal men.

In search of a physiological marker of depression and suicidal behavior, serotonin receptors of the 5-HT2 type were studied on platelet membranes from 19 control and 22 suicidal subjects. All were young, drug- and medication free men (18-21-years-old). 5-HT2 receptor binding was assayed using tritiated ketanserin at two concentrations. Receptor binding in the suicidal subjects was significantly higher than controls at both concentrations, the mean difference being around 50%. A similar difference between patients with major depressive disorder and matched controls has been observed previously. These findings support the use of 5-HT2 receptors on platelets as a research and diagnostic tool in depression and suicide.

Adolescent↗

[Competency for military arrest as a psychiatric problem].

Military law does not invest physicians with the authority to determine whether a soldier is competent when faced with military arrest, as this is a legal determination. Therefore, medical (or psychiatric) examination carried out before or during military arrest or detention, is aimed at preventing deterioration in the health of the imprisoned soldier. Hence, medical opinion serves only as a "credential" of sorts, the formal language of the military law. In reality, the examining psychiatrist has to consider many factors, including the probability that his conclusions will provide an important basis for the decision of the military legal officer as to whether to enforce military arrest. To illustrate the complicated considerations facing military psychiatrists, several case reports are presented of patients examined in the Israel Defence Forces central psychiatric clinic as to competency for military arrest.

Forensic Psychiatry↗

[Combat stress reaction].

The case of an atypical combat reaction in a 32-year-old soldier is presented. The initial phenomenon was a self-inflicted gunshot wound of the foot, while the post-traumatic symptoms appeared after a latent period 10 months. The combat stress reaction itself was identified during psychotherapy as the reactivation of trauma experienced in a previous war. Dimensions highlighted by this case include functional versus clinical measures used in diagnosis, and therapeutic considerations, such as the principles of immediacy, proximity and expectancy involved in the immediate combat stress reaction and thereafter.

Adult↗