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Biomedical subjects

A Gruchała

Publications and source records attributed to A Gruchała.

34 records · Page 2Linked to original sources
PubMed1994

Comparative flow cytometric DNA analysis on fresh and paraffin-embedded tumor tissue in different neoplasms.

The results of flow cytometric DNA-analysis on fresh and paraffin-embedded tissue were compared in four various groups of tumors. The best correlation of the results was observed in the group of non Hodgkin's lymphomas. Comparative analysis of the ploidy on fresh and paraffin embedded tissue demonstrated discordance in particular in mammary carcinoma and malignant melanoma groups. The values of proliferative fraction assessed on fresh and paraffin embedded tissues were interrelated.

Breast Neoplasms↗
PubMed1992

Synovial sarcoma: a new approach to the histological classification and a comparison with malignant mesothelioma. Immunohistochemical study with anti-mesothelial cell serum.

Routine paraffin-embedded sections from synovial sarcomas in 70 patients were stained immunohistochemically with monoclonal anti-cytokeratin antibody and serum against mesothelial cells. Positive reactions occurred in the epithelioid cells of biphasic tumors only. On the ground of the reaction with anti-mesothelial serum a hypothetical scheme of cell differentiation in synovial sarcoma was set up.

Antibodies, Monoclonal↗
PubMed1991

Alveolar soft part sarcoma: an analysis of 8 cases. Review of the literature.

Eight cases of alveolar soft part carcinoma (ASPS) are presented. The average age of the patients was 28 years. There were 6 women and 2 men. The left sided and right sided tumours were equal in number. Local recurrence was not observed in any of the patient treated, but lung metastases occurred in 6 of them. Three patients died with disease the average 35 months after treatment. Histologically in one case the uniform sheets of cells were observed without alveolar arrangement. The presence of beta glucuronidase (BG), acid phosphatase (AP) and non specific esterase (NE) in tumor cells was seen in one case studied. Immunohistochemical and ultrastructural examination confirm the thesis, that ASPS consist a distinct clinico-morphologic entity, the histogenesis of which remains uncertain.

Adolescent↗
PubMed1990

[Morphological and clinical evaluation of non-epithelial and mixed neoplasms of the female reproductive organs. II. Leiomyosarcoma].

Among 12886 malignant neoplasms of female sex organ 34 leiomyosarcoma were found. Average age of suffering women was 50 years. Metrorrhagia and lower abdominal pain were most common symptoms reported. Surgical treatment was supplemented with radiotherapy. Significant impact on prognosis showed: number of mitoses, number of bizarre and giant cells, massive necrosis and hyalinization. Efficient early diagnosis these neoplasms still awaits improvement.

Adult↗
PubMed1990

Pleural mesothelioma. Morphological characteristics of 17 cases.

Pleural mesotheliomas are rare tumors. Thus, only few reports are based on a material sufficient for reviewing the whole spectrum of pathomorphological features. This has stimulated this review of morphological characteristics of 17 pleural mesotheliomas.

Adolescent↗
PubMed1989

[Presence of lysozyme and alpha 1-antichymotrypsin in tumors of the fibrous histiocytoma type. Immunohistochemical evaluation of 52 cases].

In 52 cases of fibrohistiocytic sarcoma activity of alfa-1-antichymotripsin (ACT) in tumour cells was found in 47 cases and lysozyme in 16 cases. ACT was found in all types of tumour except angiomatous. Lysozyme was positive only in pleomorphic type, all these cases have also activity of ACT. Investigated enzymes are useful in diagnosis with correlation to others markers used in diagnostic procedure of soft tissue tumours.

Adult↗