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Biomedical subjects

A Grundy

Publications and source records attributed to A Grundy.

At least 19 recordsLinked to original sources

The Strecker Esophageal stent in the management of oesophageal strictures: technique of insertion and early clinical experience.

The Strecker Esophageal stent (Boston Scientific Corporation) offers potential palliation of oesophageal and oesophago-gastric obstruction by means of a self-expanding metal stent. This stent has been used in a series of 12 patients with oesophageal and oesophago-gastric obstruction. Initial experience of stent deployment and early clinical experience is presented.

Aged

The radiological management of gastrointestinal strictures and other obstructive lesions.

Balloon dilation of gastrointestinal strictures using a radiologic, endoscopic or combined approach is a safe, effective means of managing an ever-increasing variety of stricturing processes. At present the ability to dilate strictures in the gastrointestinal tract is limited mainly by access. Balloon dilation is now well established in the management of oesophageal and anastomotic lesions. The place of balloon dilation in the management of Crohn's disease and in the management of malignant disease requires further evaluation.

Catheterization

Case report: obstructive jaundice secondary to an intussuscepting duodenal villous adenoma.

Small intestinal tumours are rare, forming 1% of all gastrointestinal tumours; most occur in the duodenum. Villous adenomas form only a very small proportion of the duodenal tumours. They usually occur in the periampullary region and show a marked propensity for malignant change. The usual mode of presentation is with non-specific pain, jaundice or occult bleeding. Obstruction and pancreatitis are infrequent clinical presentations. Intussusception secondary to a duodenal tumour of any histological type is rarer still. A case of intussusception of a villous adenoma resulting in obstructive jaundice is described.

Adenoma

Tuberculous broncho-oesophageal fistula in the acquired immunodeficiency syndrome.

Mycobacteria are the most common bacterial infections occurring in AIDS patients. Although the gastrointestinal tract is commonly involved, there has been only one case report of oesophageal infection. We report a patient in whom oesophageal tuberculosis was the presenting feature of AIDS and review the features of mycobacterial infections in AIDS. The incidence of extrapulmonary infection is common and mycobacterial oesophagitis should be considered in the differential diagnosis of oesophagitis in AIDS.

Acquired Immunodeficiency Syndrome

Technical report: percutaneous treatment of a pancreatic duct fistula facilitated by an hydrophilic guide wire.

A case in which a pancreatico-cutaneous fistula was successfully treated percutaneously is presented. The use of an hydrophilic guide wire enabled a catheter to be negotiated across an irregular abscess cavity and into the occluded main pancreatic duct. The low friction and good flexibility of hydrophilic guide wires can greatly facilitate difficult procedures.

Catheterization

Duodenal pseudotumour: a silent impacted common bile duct calculus.

We report the case of a man with mild dyspeptic symptoms referred for barium meal, who was initially thought to have a duodenal tumour. Subsequent investigation showed this to be a pseudotumour caused by impaction of a gallstone in the distal common bile duct, and endoscopic sphincterotomy effected a cure. This readily treatable condition should be remembered when filling defects are demonstrated in the duodenal loop.

Ampulla of Vater

Balloon dilatation of upper gastrointestinal tract strictures.

Balloon dilatation has been performed in a series of 30 patients with strictures of the upper gastrointestinal tract over a period of 28 months. The technique of balloon dilatation is described and the results of follow-up are presented. Sixty per cent of patients have remained symptom-free following balloon dilatation. Twenty-seven per cent of patients have undergone regular repeated dilatations when symptoms have recurred. There were no complications from the technique. Balloon dilatation is a safe and acceptable alternative to conventional methods of bougienage in the management of upper gastrointestinal tract strictures.

Aged

The intragastric balloon: a novel idea proved ineffective.

Twelve grossly obese patients who weighed 121 +/- 22 kg (mean +/- s.d.) had a free-floating 600 ml spherical intragastric balloon inserted per oesophagus and have been followed for 12-24 months. Nine patients lost up to 21 kg (11 +/- 6.4 kg) over 3 months after which they reached a plateau and then regained weight so that by 1 year only one patient had maintained her weight loss. Three patients could not tolerate the balloon owing to complete reflex inhibition of gastric emptying. Such marginal and temporary weight loss is of no value in the treatment of gross obesity.

Adult

Percutaneous transhepatic cholangiography in the investigation of the persistent postoperative bile leak.

Percutaneous transhepatic cholangiography (PTHC) is now a widely available, inexpensive investigation with a low incidence of complications, especially in the nonobstructed system, and a high success rate. Its role in the management of obstructive jaundice is well established but it is only infrequently performed in the investigation of persistent bile leakage following biliary tract surgery. Four cases are reported in which the superior demonstration of biliary anatomy provided by PTHC allowed successful identification of the site of postoperative biliary leakage. We compared PTHC with other diagnostic imaging techniques available and conclude that it is a safe, accurate, and reliable technique.

Adenocarcinoma

Radiological appearances following vertical banded gastroplasty.

Vertical banded gastroplasty was performed on 19 grossly obese patients. Upper gastrointestinal contrast studies were performed on all patients in the immediate post-operative period and at 3 months and 1 year in 16 and 12 patients, respectively. The immediate and long-term appearances are presented and discussed. The surgical outcome depends on pouch size, outlet diameter and staple line integrity, which are reliably demonstrated by double-contrast barium studies.

Adult