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Biomedical subjects

A Guigui

Publications and source records attributed to A Guigui.

13 recordsLinked to original sources
PubMed1990

[Contrast sensitivity and diabetes].

Contrast sensitivity has been assessed in 24 diabetic patients in order to test the hypothesis that contrast sensitivity is impaired in the early stages of diabetes mellitus. All patients had 20/20 vision. Some evidence of visual dysfunction was observed in 33% of the diabetics with no retinopathy and 83% of the 6 patients with retinopathy when compared to 48 age-matched controls. Contrast sensitivity was mainly reduced in the mid-range spatial frequencies and correlated with the degree of retinopathy. The accurate assessment of visual dysfunction in diabetes is very important, as new drugs (i.e. aldose reductase inhibitors) are currently under evaluation.

Contrast Sensitivity↗
PubMed1989

[Vitreous hemorrhage and neovascular proliferation in multiple sclerosis].

We report the case of a 40 year-old man with multiple sclerosis, who presented a bilateral proliferative retinopathy responsible for a vitreous hemorrhage. Examination of the periphery of the retina showed diffuse retinal periphlebitis; fluorescein angiograms showed a peripheral retinal ischemic syndrome with secondary neovascularization. Several recent studies have show that retinal periphlebitis is a frequent finding in multiple sclerosis; but to our knowledge a retinal ischemic syndrome with neovascularization has seldom been reported.

Adult↗
PubMed1987

[Trabeculectomy. Long-term retrospective study].

Long term follow up of 51 eyes treated by trabeculectomy between 1975 and 1978. The pressure remains below 20 mmHg in 94% of our cases and progression field loss is stopped in 60%. The control of pressure needs adjunction of a medical treatment in 47% of cases. Progression of glaucomatous field loss is stopped when the ocular pressure is very low (40% or more of initial pressure). Cataract is seen in oldest patients. These observations suggest that: glaucoma surgery must give a sufficient drop of ocular pressure in all cases with pressure between 15 and 20 adjuvant medical therapy is useful old patients are a poor material for glaucoma surgery.

Age Factors↗
PubMed1986

[Multifocal inner choroiditis: pseudohistoplasmosis. The European form of the presumed American histoplasmosis].

We studied nine patients with the picture of presumed ocular histoplasmosis. All patients had the characteristic triad: punched out peripheral lesions, peripapillary atrophic scar and disciform process in the posterior pole. All patients had negative test for histoplasmosis (electrosyneresis). Four patients were observed for a long period (8, 8, 7 and 4 years). In two cases we could observe the first step of the basic choroidal lesions. One of these patients fundus was previously normal. Age, female to male ratio and in one case mild inflammatory lesions were similar to a new entity: multifocal choroiditis. The cause of European disseminated inner choroiditis remains unknown. There may be one or multiple causative agents including unidentified fungus.

Adolescent↗
PubMedDate not supplied

[Atypical tapetoretinal degeneration simulating a neurologic syndrome].

We report the case of a 57-year-old woman with progressive bilateral visual acuity loss, presumed during ten years to be secondary to a neurological disease. Ophthalmological examination showed for both eyes pallor of the optic discs and arteriolar narrowing. Periphery was normal, without pigment clumping. Fluorescein angiography showed a widespread irregular hypopigmentation and discovered a bilateral macular edema. Abnormal rod function was confirmed by electroretinography. A review of the literature data shows the variety of clinical symptoms in patients with retinitis pigmentosa and the frequency of atypical non-pigmented forms. Those forms are usually considered as early stages of the disease. Besides, macular lesions, and macular edema in particular, are frequently reported.

Diagnosis, Differential↗