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Biomedical subjects

A H Kafrawy

Publications and source records attributed to A H Kafrawy.

At least 55 records · Page 3Linked to original sources

Uptake and release of chlorhexidine by bovine pulp and dentin specimens and their subsequent acquisition of antibacterial properties.

Bovine pulp and dentin specimens were treated with either a 0.02 or 1.00 percent solution of chlorhexidine for either 20 or 40 minutes. Culture determination of the acquisition of antibacterial properties by the treated specimens immediately and 1 week after the treatment was evaluated using the test organism Streptococcus faecalis. It was concluded that chlorhexidine is a potent antibacterial agent under the test conditions and that its use as an endodontic irrigating solution should be further evaluated.

Adsorption↗

The relationship of Bacteroides melaninogenicus to symptoms associated with pulpal necrosis.

The canal contents of thirty-three cariously and traumatically exposed pulpless teeth were sampled with a special technique and cultured anaerobically for growth in prereduced thioglycollate and for Bacteroides melaninogenicus on selective blood agar plates. The presence of B. melaninogenicus was compared with the presence or absence of eight symptoms associated with pulpal necrosis and the presence or absence of growth in thioglycollate. B. melaninogenicus was found to be significantly related to pain, sinus tract formation and foul odor. Suggested relationships were found between the organism and the presence of apical sensitivity and local swelling. Growth in prereduced thioglycollate occurred more often from teeth in which B. melaninogenicus was present. With the sampling technique used, positive growth in the thioiglycollte ranged from 88 percent at the initial appointment to 72 percent at the fill appointment.

Adolescent↗

Comparison of Dycal and formocresol pulpotomies in young permanent teeth in monkeys.

This study compared Dycal and formocresol pulpotomies on young healthy permanent teeth with respect to continued dentinogenesis and root end development. Pulpotomy was performed on a total of forty permanent teeth with incompletely developed roots in three young stump-tailed monkeys (Macaca speciosa). Twenty teeth were treated with Dycal and twenty with formocresol. At the end of the experimental periods the animals were killed and the specimens were prepared and sectioned en bloc for histologic examination. The interval between treatment and death ranged between 7 and 797 days. Before each experimental procedure a Procion vital dye was administered as a marking agent for continued root development. Twelve of twenty teeth treated with Dycal and seventeen of twenty teeth treated with formocresol were judged to be successful as evidenced by continued root development, absence of periapical pathoses, and the presence of noninflamed or only mildly inflamed pulps. Brown and Brenn staining showed bacteria within the pulps of the teeth that failed. All but one of the teeth in this study showed evidence of continued root development as confirmed by Procion labeling.

Animals↗

Pulp reaction to a tricalcium phosphate ceramic capping agent.

A porous form of tricalcium phosphate ceramic has been shown to stimulate new bone formation around the implant. The purpose of the present study was to evaluate this material in a powder form as a pulp-capping material. It was found difficult to cover a pulp exposure adequately with Synthos ceramic powder alone. Histologic sections showed dentinogenesis around those particles which were forced into the pulp proper, demonstrating the nonirritating potential of Synthos. Because of the bacterial infection in so many of the specimens, this study is inconclusive with respect to the use of this material as a capping agent. A similar study, employing a rubber dam to protect the exposure, is recommended.

Animals↗

Effect of autogenous marrow and calcitonin on reactions to a ceramic.

The effect of autogenous marrow and calcitonin on reactions to a tricalcium phosphate ceramic was studied by subcutaneous implantation in rats. No bone formation was evident in association with uncoated and calcitonin-coated ceramic. At four weeks and thereafter bone formation was evident in association with all marrow-coated implants.

Animals↗

Medications and health histories: a survey of 4,365 dental patients.

Dental patients were surveyed to determine the medications they were using and to compile information on their medical histories. Complete survey forms were obtained from 4,365 patients who were seen for emergency treatment or for diagnosis and treatment planning between August 1975 and July 1976. Of the patients surveyed, 1,833 (42%) were taking medications. The frequency of intake of different drug groups was: analgesics, 14.2%; oral contraceptives, 12.1%; antihypertensives, 9.4%; miscellaneous (vitamins, antacids, anorectics, nonprescription cold remedies), 9.4%; psychotherapeutic agents, 7.6%; hormones, 6.6%; antibiotics, 4.9%; antihistamines, 3.8%; cardiac agents, 3.1%; hypoglycemics, 2.0%; anticonvulsants, 0.9%; antiasthmatics, 0.6%; and anticoagulants, 0.2%. At least one significant medical problem was reported by 2.989 patients (68.5%). The frequency of positive responses in the various groups was: hospitalizations, 40.5%; genitourinary problems, 19.8%; allergies, 19.2%; respiratory problems, 17.9%; gastrointestinal problems, 15.5%; cardiovascular disorders, 15.1%; musculoskeletal disorders, 12.6%; eye and ear afflictions, 8.3%; endocrine disorders, 6.5%; serious illness, 6.5%; disorders of the central nervous system, 5.9%; and disorders of integument, 4.9%

Adolescent↗

Oral manifestations of acute leukemia in children.

Seventy-seven children with acute leukemia were examined. A wide spectrum of oral findings was observed as the consequence of direct leukemic infiltration of tissue, infection resulting from bone marrow and immunosuppression, impaired healing responses, and poor oral hygiene. Guidelines for dental treatment are provided.

Adolescent↗