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Biomedical subjects

A H Letton

Publications and source records attributed to A H Letton.

At least 19 recordsLinked to original sources
PubMed1989

Routine breast screening for cancer.

Breast screening for cancer has increased the survival for women over age 50 as well as those younger than 50 years old. The 13-year average follow-up period disproves the claim that the survival gain is due to lead-time bias. The information brought forth in this presentation proves that higher-risk women must be screened in order to reduce the constant death rate from breast cancer.

Breast↗
PubMed1986

Routine breast screening. Survival after 10.5 years follow-up.

Beginning in 1973, the Breast Cancer Detection Demonstration Project at Georgia Baptist Medical Center screened 8058 supposedly asymptomatic volunteers. Those screenees found to have cancer were treated by various surgeons, using all types of treatment with varying expertise. There has been 100% follow-up after 10.5 years. The overall survival is 90.8%. The women over 50 in all categories survived longer than the younger age group. Those women with lesions 1 cm or smaller survived longer than those with larger lesions. The women whose tumor was not palpable clinically and was discovered by roentgenogram had the best survival rates (96.8%). In the less-than-50 age group whose cancer was detected by roentgenogram alone, 88.2% survived 10.5 years, while 100% of the older group is still living. These results do not consider the type of therapy nor the skill with which it was administered and is the result of routine screening only.

Age Factors↗
PubMed1977

The value of breast screening in women less than fifty years of age.

In the four years our Breast Cancer Detection Demonstration Project has been receiving patients, 5,810 women under the age of fifty have been examined. Our findings definitely indicate screening of asymptomatic women by xeromammography is of advantage in this group whose greatest cause of death is cancer of the breast; 71.8% of their cancers were found by xeromammography. Of these 43.8% had in situ cancer and only 12.5% of those cancers found had axillary spread. This group should have a five-year cure rate of 87.1% rather than 63% as is the experience of unscreened women. The absorbed rads averaged 0.4632 to each breast per year. At the end of five years this would cause an estimated increase in risk from 7% to 7.162%. To increase survival rate by 24.1% against a theoretical increased risk of 0.16% is definitely worthwhile.

Adult↗
PubMed1975

Surgical management of carotid body tumor.

Carotid body tumor or chemodectoma is a slow-growing lesion; it should be diagnosed early to facilitate the technical surgical resection. When these lesions are large, the routine use of a carotid internal bypass shunt is advocated for their safe removal. With the newer vascular approaches, specifically the carotid internal bypass shunt, resection can be performed with acceptable risks. A patient with large bilateral carotid body tumors had successful resection of both these lesions.

Carotid Body Tumor↗
PubMed1974

Cancer control.

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Female↗