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Biomedical subjects

A H Masson

Publications and source records attributed to A H Masson.

15 recordsLinked to original sources

Two early ether inhalers.

The existence of two of the earliest ether inhalers, a Squire's inhaler and a Tracy's inhaler, in the Museum of the Royal College of Surgeons of Edinburgh is recorded.

Anesthesia, Inhalation

Reports by anaesthetists to procurators-fiscal: analysis of "anaesthetic deaths" over 10 years in four Scottish teaching hospitals.

Review of 489 "anaesthetic deaths" reported to procurators-fiscal over 10 years disclosed only 30 that were thought to justify such reporting. Most of the remainder occurred in patients so desperately ill at the time of operation that death was expected. Postmortem examinations ordered by the Crown authorities in nearly all cases were probably largely unrewarding and mostly unnecessary. The results suggest that the present regulation on reporting should be revised to focus more attention on the few deaths that occur in patients who have no apparent contraindication to anaesthesia or operation.

Adult

Impairment of oxygen transfer in the lung by increasing oxygen concentration during halothane and trichloroethylene anaesthesia.

Two groups of 10 patients were studied during artificial ventilation with a mixture of oxygen, nitrogen and either halothane or trichloroethylene. Arterial blood and respiratory gas smapling was performed at FIO2 values of 0.33, 0.5 and 0.75. The efficiency of oxygen transfer, expressed as the difference between pulmonary end-capillary and arterial oxygen content, was found to decrease progressively in most patients as the alveolar partial pressure of oxygen increased. This pattern of response may be explained by the effect of oxygen on regulatory reflexes in the lung.

Adult

Severe fat embolism: a review of 24 cases.

Twenty-four patients suffering from fat embolism syndrome, severe enough to warrant transfer to an artificial ventilation unit, are reviewed. All developed the condition following trauma. Five patients were managed with oxygen therapy and sedation, but the other 19 needed intubation and ventilation to achieve adequate arterial oxygenation. In spite of intensive supportive therapy, 6 patients (who had all required ventilation) died, one due to heparin therapy, the others from progression of the syndrome. A poor prognosis seemed to be associated with young age, a rapidly progressive condition and a continued need for 100 per cent oxygen after institution of artificial ventilation. There seemed to be no relationship between outcome and severity of injury, type of surgical management and time of onset after injury. The clinical features of these patients are discussed with reference to the many unanswered questions that surround this condition.

Adolescent