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Biomedical subjects

A H Sheriffdeen

Publications and source records attributed to A H Sheriffdeen.

13 recordsLinked to original sources
PubMed1995

Fine needle sampling without aspiration.

Four hundred and ten thyroid nodules, 127 breast lumps and 43 lymph nodes were sampled and analyzed to compare the classical aspiration (ASP) technique with the non aspiration needle jab (NASP) technique. The adequacy of cellularity, significant blood staining and the discomfort felt by the patient were assessed and statistically analyzed. The non aspiration technique was found to be superior to the classical aspiration technique for fine needle sampling of thyroid in all aspects. However, for breast lesions, while the discomfort felt and the staining with blood was less with the non aspiration technique, the overall cellular yield was unsatisfactory. The adequacy of cellular yield was, however, comparable for malignant breast lesions with either technique. For lymph node sampling, both techniques showed equivalent results with regard to the cellularity but, the NASP technique was superior in other aspects. Although the overall patient discomfort and blood staining was significantly less, the adequacy of the cellularity was influenced by the site and the nature of the lesion. Thus it can be concluded that the technique needs to be selected depending on the anatomic site, the clinical situation, the personal experience and the preference of the operator.

Biopsy, Needle↗
PubMed1995

Emergency femoral arteriography in lower limb vascular trauma.

There are difficulties in obtaining emergency arteriographic evaluation in lower limb vascular trauma even in the best centres in the world. Ten emergency room arteriograms were performed at the new Accident Service of the General Hospital, Colombo from February to October 1992 by the vascular team, using a venous cannula and improvised tubing systems. The indications were, absence of distal pulses with closed injury to the limb, previous attempts at repair, injury to the limb at more than one site and multiple shrapnel injury. A traumatic arteriovenous communication was shown in one of the arteriograms. Unnecessary exploration of the artery was prevented by the demonstration of a patent femoropopliteal segment in two cases. The average delay caused by this procedure was less than one hour, which compares well with centres in the West. Provision of an arteriogram kit at the Accident Service will help to overcome practical problems.

Blood Vessels↗
PubMed1993

Aspiration cytology of breast lumps.

The results of 287 aspirations performed on palpable breast lumps over a period of 20 months are presented. This is the first documentation of a Sri Lankan experience of this technique. The cytological assessment showed 52 malignant, 149 benign, 8 atypical, 6 suspicious and 72 inadequate aspirates. All lesions with a cytological diagnosis of malignancy were confirmed by histological assessment (False positives = 0). Histological follow up in 96 of the 149 cytologically benign lesions showed that 2 were malignant, giving a false negative rate of 2.1%. Three atypical lesions (37.5%) and four suspicious (66.2%) and 10 inadequate aspirates (13.7%) were also malignant.

Biopsy, Needle↗
PubMed1978

Transient emboligenic aortoarteritis. Noteworthy new entity in young stroke patients.

The clinical and postmorten anatomical data in a group of ten patients with occlusive cerebrovascular disease in the 15- to 40-year group were studied. The occlusion of the peripheral supply artery in the brain in all cases was found to be due to thromboemboli generated from focal thrombotic lesions situated proximally in the aorta and elastic arterial trunks arising from it. These central thrombotic lesions were caused by a transient form of focal aortoarteritis that primarily affects medial elastic tissue underlying the thrombi. This is a new disease entity, distinct from Takayasu's and other forms of segmental aortitis. The pathogenesis of occlusive cerebrovascular disease in the young remains obscure in a majority of cases. In this context, the definition of this new entity is an important contribution to the understanding of nonatherogenic occlusive cerebrovascular disease.

Adolescent↗